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Here, we describe the photomotor response (PMR), a robust and reproducible series of motor behaviors in zebrafish that is elicited by visual wavelengths of light but does not require the eyes, pineal gland, or other canonical deep-brain photoreceptive organs. Unlike the relatively slow effects of canonical nonvisual pathways, motor circuits are strongly and quickly (seconds) recruited during the PMR behavior. We find that the hindbrain is both necessary and sufficient to drive these behaviors. Using<jats:italic>in vivo<\/jats:italic>calcium imaging, we identify a discrete set of neurons within the hindbrain whose responses to light mirror the PMR behavior. Pharmacological inhibition of the visual cycle blocks PMR behaviors, suggesting that opsin-based photoreceptors control this behavior. These data represent the first known light-sensing circuit in the vertebrate hindbrain.<\/jats:p>","DOI":"10.1523\/jneurosci.3689-12.2013","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T18:13:28Z","timestamp":1361988808000},"page":"3834-3843","source":"Crossref","is-referenced-by-count":114,"title":["Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain"],"prefix":"10.1523","volume":"33","author":[{"given":"David","family":"Kokel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy W.","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misha 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