{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T12:00:15Z","timestamp":1773057615221,"version":"3.50.1"},"reference-count":66,"publisher":"Society for Neuroscience","issue":"11","license":[{"start":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T00:00:00Z","timestamp":1316131200000},"content-version":"vor","delay-in-days":184,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurosci."],"published-print":{"date-parts":[[2011,3,16]]},"abstract":"<jats:p>To compare with our previous findings on relative-duration discrimination, we studied prefrontal cortex activity as monkeys performed a relative-distance discrimination task. We wanted to know whether the same parts of the prefrontal cortex compare durations and distances and, if so, whether they use similar mechanisms. Two stimuli appeared sequentially on a video screen, one above a fixed reference point, the other below it by a different distance. After a delay period, the same two stimuli reappeared (as choice stimuli), and the monkeys' task was to choose the one that had appeared farther from the reference point during its initial presentation. We recorded from neurons in the dorsolateral prefrontal cortex (area 46) and the caudal prefrontal cortex (area 8). Although some prefrontal neurons encoded the absolute distance of a stimulus from the reference point, many more encoded relative distance. Categorical representations (\u201cfarther\u201d) predominated over parametric ones (\u201chow much farther\u201d). Relative-distance coding was most often abstract, coding the farther or closer stimulus to the same degree, independent of its position on the screen. During the delay period before the choice stimuli appeared, feature-based coding supplanted order-based coding, and position-based coding\u2014always rare\u2014decreased to chance levels. The present results closely resembled those for a duration-discrimination task in the same cortical areas. We conclude, therefore, that these areas contribute to decisions based on both spatial and temporal information.<\/jats:p>","DOI":"10.1523\/jneurosci.5373-10.2011","type":"journal-article","created":{"date-parts":[[2011,3,16]],"date-time":"2011-03-16T17:24:43Z","timestamp":1300296283000},"page":"3968-3980","source":"Crossref","is-referenced-by-count":47,"title":["Prefrontal Cortex Activity during the Discrimination of Relative Distance"],"prefix":"10.1523","volume":"31","author":[{"given":"Aldo","family":"Genovesio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Tsujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven P.","family":"Wise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"393","published-online":{"date-parts":[[2011,3,16]]},"reference":[{"key":"2023041303493041000_31.11.3968.1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4483-06.2007"},{"key":"2023041303493041000_31.11.3968.2","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00221-003-1416-6","article-title":"Neural activity in prefrontal cortex during copying geometrical shapes. 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