{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:10:11Z","timestamp":1791407411008,"version":"4.3.3"},"reference-count":105,"publisher":"Society for Neuroscience","issue":"18","license":[{"start":{"date-parts":[[2011,11,4]],"date-time":"2011-11-04T00:00:00Z","timestamp":1320364800000},"content-version":"vor","delay-in-days":184,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Neurosci."],"published-print":{"date-parts":[[2011,5,4]]},"abstract":"<jats:p>\n                    The origin of GnRH-1 cells and olfactory ensheathing cells has been controversial. Genetic Cre-lox lineage tracing of the neural crest (NC) versus ectodermal contribution to the developing nasal placode was performed using two complementary mouse models, the NC-specific\n                    <jats:italic>Wnt1Cre<\/jats:italic>\n                    mouse line and an ectodermal-specific\n                    <jats:italic>Crect<\/jats:italic>\n                    mouse line. Using these lines we prove that the NC give rise to the olfactory ensheathing cells and subpopulations of GnRH-1 neurons, olfactory and vomeronasal cells. These data demonstrate that Schwann cells and olfactory ensheathing cells share a common developmental origin. Furthermore, the results indicate that certain conditions that impact olfaction and sexual development, such as Kallmann syndrome, may be in part neurocristopathies.\n                  <\/jats:p>","DOI":"10.1523\/jneurosci.6087-10.2011","type":"journal-article","created":{"date-parts":[[2011,5,4]],"date-time":"2011-05-04T13:01:28Z","timestamp":1304514088000},"page":"6915-6927","source":"Crossref","is-referenced-by-count":220,"title":["Neural Crest and Ectodermal Cells Intermix in the Nasal Placode to Give Rise to GnRH-1 Neurons, Sensory Neurons, and Olfactory Ensheathing Cells"],"prefix":"10.1523","volume":"31","author":[{"given":"Paolo Emanuele","family":"Forni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Taylor-Burds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vida 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