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Usually, many stem cells are virally transduced to obtain a sufficient number of genetically corrected cells required for successful transplantation, as genetic insertion in every stem cell cannot be precisely defined. In this issue of\n                    <jats:italic>EMBO Molecular Medicine<\/jats:italic>\n                    , Droz\u2010Georget Lathion\n                    <jats:italic>et\u00a0al<\/jats:italic>\n                    developed a new strategy for\n                    <jats:italic>ex vivo<\/jats:italic>\n                    single cell gene therapy that allows extensive genomic and functional characterization of the genetically repaired individual cells before they can be used in clinical settings.\n                  <\/jats:p>","DOI":"10.15252\/emmm.201404859","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T21:58:04Z","timestamp":1425074284000},"page":"366-367","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Single stem cell gene therapy for genetic\u00a0skin disease"],"prefix":"10.1038","volume":"7","author":[{"given":"Jean\u2010Christophe","family":"Larsimont","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9dric","family":"Blanpain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"BFEMMM201404859_CR1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0945-053X(98)00007-9","volume":"18","author":"L Bruckner\u2010Tuderman","year":"1999","unstructured":"Bruckner\u2010Tuderman L, Hopfner B, Hammami\u2010Hauasli N (1999) Biology of anchoring fibrils: lessons from dystrophic epidermolysis bullosa. 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