{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:27:25Z","timestamp":1779114445109,"version":"3.51.4"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Portuguese National Funding","award":["PPBI\u2010POCI\u201001\u20100145\u2010FEDER\u2010022122"],"award-info":[{"award-number":["PPBI\u2010POCI\u201001\u20100145\u2010FEDER\u2010022122"]}]},{"name":"Research Infrastructure Congento","award":["LISBOA\u201001\u20100145\u2010FEDER\u2010022170"],"award-info":[{"award-number":["LISBOA\u201001\u20100145\u2010FEDER\u2010022170"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["PTDC\/BEX\u2010BID\/0395\/2014"],"award-info":[{"award-number":["PTDC\/BEX\u2010BID\/0395\/2014"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UID\/BIM\/04773\/2013 CBMR 1334"],"award-info":[{"award-number":["UID\/BIM\/04773\/2013 CBMR 1334"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["SFRH\/BPD\/84214\/2012"],"award-info":[{"award-number":["SFRH\/BPD\/84214\/2012"]}]},{"name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["IF\/01341\/2012"],"award-info":[{"award-number":["IF\/01341\/2012"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["EMBO Rep"],"published-print":{"date-parts":[[2018,8,1]]},"DOI":"10.15252\/embr.201845728","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T06:05:11Z","timestamp":1532325911000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The Trithorax group protein dMLL3\/4 instructs the assembly of the zygotic genome at fertilization"],"prefix":"10.1038","volume":"19","author":[{"given":"Pedro","family":"Prud\u00eancio","sequence":"first","affiliation":[]},{"given":"Leonardo G","family":"Guilgur","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o","family":"Sobral","sequence":"additional","affiliation":[]},{"given":"J\u00f6rg D","family":"Becker","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1641-3403","authenticated-orcid":false,"given":"Rui Gon\u00e7alo","family":"Martinho","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8543-4179","authenticated-orcid":false,"given":"Paulo","family":"Navarro\u2010Costa","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2018,7,23]]},"reference":[{"key":"BFEMBR201845728_CR1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/nrm3643","volume":"14","author":"D Clift","year":"2013","unstructured":"Clift D, Schuh M (2013) Restarting life: fertilization and the transition from meiosis to mitosis. Nat Rev Mol Cell Biol 14: 549\u2013562","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"Spec No. 1","key":"BFEMBR201845728_CR2","doi-asserted-by":"crossref","first-page":"R47","DOI":"10.1093\/hmg\/ddi114","volume":"14","author":"HD Morgan","year":"2005","unstructured":"Morgan HD, Santos F, Green K, Dean W, Reik W (2005) Epigenetic reprogramming in mammals. Hum Mol Genet 14 (Spec No. 1): R47\u2013R58","journal-title":"Hum Mol Genet"},{"key":"BFEMBR201845728_CR3","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nrm3885","volume":"15","author":"A Burton","year":"2014","unstructured":"Burton A, Torres\u2010Padilla M\u2010E (2014) Chromatin dynamics in the regulation of cell fate allocation during early embryogenesis. Nat Rev Mol Cell Biol 15: 723\u2013734","journal-title":"Nat Rev Mol Cell Biol"},{"key":"BFEMBR201845728_CR4","doi-asserted-by":"crossref","first-page":"150076","DOI":"10.1098\/rsob.150076","volume":"5","author":"B Loppin","year":"2015","unstructured":"Loppin B, Dubruille R, Horard B (2015) The intimate genetics of Drosophila fertilization. Open Biol 5: 150076","journal-title":"Open Biol"},{"key":"BFEMBR201845728_CR5","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.gde.2009.03.004","volume":"19","author":"M Albert","year":"2009","unstructured":"Albert M, Peters AHFM (2009) Genetic and epigenetic control of early mouse development. Curr Opin Genet Dev 19: 113\u2013121","journal-title":"Curr Opin Genet Dev"},{"key":"BFEMBR201845728_CR6","volume-title":"The maternal\u2010to\u2010zygotic transition","author":"HD Lipshitz","year":"2015","unstructured":"Lipshitz HD (2015) The maternal\u2010to\u2010zygotic transition. Amsterdam, The Netherlands: Academic Press"},{"key":"BFEMBR201845728_CR7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0092-8674(92)90466-P","volume":"68","author":"DS Johnston","year":"1992","unstructured":"Johnston DS, N\u00fcsslein\u2010Volhard C (1992) The origin of pattern and polarity in the Drosophila embryo. Cell 68: 201\u2013219","journal-title":"Cell"},{"key":"BFEMBR201845728_CR8","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1242\/dev.039487","volume":"137","author":"L Li","year":"2010","unstructured":"Li L, Zheng P, Dean J (2010) Maternal control of early mouse development. Development 137: 859\u2013870","journal-title":"Development"},{"key":"BFEMBR201845728_CR9","doi-asserted-by":"crossref","first-page":"11871","DOI":"10.1073\/pnas.1606857113","volume":"113","author":"C Wang","year":"2016","unstructured":"Wang C, Lee J\u2010E, Lai B, Macfarlan TS, Xu S, Zhuang L, Liu C, Peng W, Ge K (2016) Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition. Proc Natl Acad Sci USA 113: 11871\u201311876","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBR201845728_CR10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S1472-6483(10)60788-2","volume":"14","author":"C Andreu\u2010Vieyra","year":"2007","unstructured":"Andreu\u2010Vieyra C, Matzuk MM (2007) Epigenetic modifications by Trithorax group proteins during early embryogenesis: do members of Trx\u2010G function as maternal effect genes? Reprod Biomed Online 14: 201\u2013207","journal-title":"Reprod Biomed Online"},{"key":"BFEMBR201845728_CR11","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/nature02080","volume":"426","author":"Y Sedkov","year":"2003","unstructured":"Sedkov Y, Cho E, Petruk S, Cherbas L, Smith ST, Jones RS, Cherbas P, Canaani E, Jaynes JB, Mazo A (2003) Methylation at lysine 4 of histone H3 in ecdysone\u2010dependent development of Drosophila. Nature 426: 78\u201383","journal-title":"Nature"},{"key":"BFEMBR201845728_CR12","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1101\/gad.201327.112","volume":"26","author":"HM Herz","year":"2012","unstructured":"Herz HM, Mohan M, Garruss AS, Liang K, Takahashi YH, Mickey K, Voets O, Verrijzer CP, Shilatifard A (2012) Enhancer\u2010associated H3K4 monomethylation by Trithorax\u2010related, the Drosophila homolog of mammalian Mll3\/Mll4. Genes Dev 26: 2604\u20132620","journal-title":"Genes Dev"},{"key":"BFEMBR201845728_CR13","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1038\/ng.3965","volume":"49","author":"R Rickels","year":"2017","unstructured":"Rickels R, Herz H\u2010M, Sze CC, Cao K, Morgan MA, Collings CK, Gause M, Takahashi Y\u2010H, Wang L, Rendleman EJ et al (2017) Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS\u2010like proteins at enhancers is dispensable for development and viability. Nat Genet 49: 1647\u20131653","journal-title":"Nat Genet"},{"key":"BFEMBR201845728_CR14","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.cell.2017.08.002","volume":"171","author":"B Schuettengruber","year":"2017","unstructured":"Schuettengruber B, Bourbon H\u2010M, Di Croce L, Cavalli G (2017) Genome regulation by polycomb and trithorax: 70 years and counting. Cell 171: 34\u201357","journal-title":"Cell"},{"key":"BFEMBR201845728_CR15","doi-asserted-by":"crossref","first-page":"aad9780","DOI":"10.1126\/science.aad9780","volume":"352","author":"A Piunti","year":"2016","unstructured":"Piunti A, Shilatifard A (2016) Epigenetic balance of gene expression by Polycomb and COMPASS families. Science 352: aad9780","journal-title":"Science"},{"key":"BFEMBR201845728_CR16","first-page":"454","volume":"25","author":"YC Tan","year":"2001","unstructured":"Tan YC, Chow VT (2001) Novel human HALR (MLL3) gene encodes a protein homologous to ALR and to ALL\u20101 involved in leukemia, and maps to chromosome 7q36 associated with leukemia and developmental defects. Cancer Detect Prev 25: 454\u2013469","journal-title":"Cancer Detect Prev"},{"key":"BFEMBR201845728_CR17","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1006\/geno.1999.5860","volume":"59","author":"KT FitzGerald","year":"1999","unstructured":"FitzGerald KT, Diaz MO (1999) MLL2: a new mammalian member of the trx\/MLL family of genes. Genomics 59: 187\u2013192","journal-title":"Genomics"},{"key":"BFEMBR201845728_CR18","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0925-4773(98)00246-9","volume":"82","author":"Y Sedkov","year":"1999","unstructured":"Sedkov Y, Benes JJ, Berger JR, Riker KM, Tillib S, Jones RS, Mazo A (1999) Molecular genetic analysis of the Drosophila trithorax\u2010related gene which encodes a novel SET domain protein. Mech Dev 82: 171\u2013179","journal-title":"Mech Dev"},{"key":"BFEMBR201845728_CR19","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1242\/dev.143347","volume":"144","author":"D Brici","year":"2017","unstructured":"Brici D, Zhang Q, Reinhardt S, Dahl A, Hartmann H, Schmidt K, Goveas N, Huang J, Gahurova L, Kelsey G et al (2017) The histone 3 lysine 4 methyltransferase Setd1bis a maternal effect gene required for the oogenic gene expression program. Development 144: 2606\u20132617","journal-title":"Development"},{"key":"BFEMBR201845728_CR20","first-page":"e1000453\u201019","volume":"8","author":"CV Andreu\u2010Vieyra","year":"2010","unstructured":"Andreu\u2010Vieyra CV, Chen R, Agno JE, Glaser S, Anastassiadis K, Stewart AF, Matzuk MM (2010) MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. PLoS Biol 8: e1000453\u201019","journal-title":"PLoS Biol"},{"key":"BFEMBR201845728_CR21","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.devcel.2014.01.020","volume":"28","author":"D Yan","year":"2014","unstructured":"Yan D, Neum\u00fcller RA, Buckner M, Ayers K, Li H, Hu Y, Yang\u2010Zhou D, Pan L, Wang X, Kelley C et al (2014) A regulatory network of Drosophila germline stem cell self\u2010renewal. Dev Cell 28: 459\u2013473","journal-title":"Dev Cell"},{"key":"BFEMBR201845728_CR22","doi-asserted-by":"crossref","first-page":"8305","DOI":"10.1073\/pnas.1019290108","volume":"108","author":"Y Xiao","year":"2011","unstructured":"Xiao Y, Bedet C, Robert VJP, Simonet T, Dunkelbarger S, Rakotomalala C, Soete G, Korswagen HC, Strome S, Palladino F (2011) Caenorhabditis elegans chromatin\u2010associated proteins SET\u20102 and ASH\u20102 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells. Proc Natl Acad Sci USA 108: 8305\u20138310","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBR201845728_CR23","first-page":"149","volume-title":"The Development of Drosophila melanogaster","author":"VF Foe","year":"1993","unstructured":"Foe VF, Odell GM, Edgar BA (1993) Mitosis and morphogenesis in the Drosophila embryo: point and counterpoint. In The Development of Drosophila melanogaster, Bate M, Arias AM (eds), pp 149\u2013300. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press"},{"key":"BFEMBR201845728_CR24","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1016\/j.cub.2006.06.024","volume":"16","author":"VL Horner","year":"2006","unstructured":"Horner VL, Czank A, Jang JK, Singh N, Williams BC, Puro J, Kubli E, Hanes SD, McKim KS, Wolfner MF et al (2006) The Drosophila calcipressin sarah is required for several aspects of egg activation. Curr Biol 16: 1441\u20131446","journal-title":"Curr Biol"},{"key":"BFEMBR201845728_CR25","doi-asserted-by":"crossref","first-page":"6165","DOI":"10.1128\/MCB.25.14.6165-6177.2005","volume":"25","author":"S Jayaramaiah Raja","year":"2005","unstructured":"Jayaramaiah Raja S, Renkawitz\u2010Pohl R (2005) Replacement by Drosophila melanogaster protamines and Mst77F of histones during chromatin condensation in late spermatids and role of sesame in the removal of these proteins from the male pronucleus. Mol Cell Biol 25: 6165\u20136177","journal-title":"Mol Cell Biol"},{"key":"BFEMBR201845728_CR26","doi-asserted-by":"crossref","first-page":"13539","DOI":"10.1038\/ncomms13539","volume":"7","author":"S Tirmarche","year":"2016","unstructured":"Tirmarche S, Kimura S, Dubruille R, Horard B, Loppin B (2016) Unlocking sperm chromatin at fertilization requires a dedicated egg thioredoxin in Drosophila. Nat Commun 7: 13539","journal-title":"Nat Commun"},{"key":"BFEMBR201845728_CR27","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/nrm3531","volume":"14","author":"R Li","year":"2013","unstructured":"Li R, Albertini DF (2013) The road to maturation: somatic cell interaction and self\u2010organization of the mammalian oocyte. Nat Rev Mol Cell Biol 14: 141\u2013152","journal-title":"Nat Rev Mol Cell Biol"},{"key":"BFEMBR201845728_CR28","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/jmor.1050390108","volume":"39","author":"AF Huettner","year":"1924","unstructured":"Huettner AF (1924) Maturation and fertilization in Drosophila melanogaster. J Morphol 39: 249\u2013265","journal-title":"J Morphol"},{"key":"BFEMBR201845728_CR29","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/dbio.1997.8506","volume":"183","author":"AW Page","year":"1997","unstructured":"Page AW, Orr\u2010Weaver TL (1997) Activation of the meiotic divisions in Drosophila oocytes. Dev Biol 183: 195\u2013207","journal-title":"Dev Biol"},{"key":"BFEMBR201845728_CR30","doi-asserted-by":"crossref","first-page":"12331","DOI":"10.1038\/ncomms12331","volume":"7","author":"P Navarro\u2010Costa","year":"2016","unstructured":"Navarro\u2010Costa P, McCarthy A, Prud\u00eancio P, Greer C, Guilgur LG, Becker JD, Secombe J, Rangan P, Martinho RG (2016) Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling. Nat Commun 7: 12331","journal-title":"Nat Commun"},{"key":"BFEMBR201845728_CR31","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.cub.2006.05.058","volume":"16","author":"S Takeo","year":"2006","unstructured":"Takeo S, Tsuda M, Akahori S, Matsuo T, Aigaki T (2006) The calcineurin regulator sra plays an essential role in female meiosis in Drosophila. Curr Biol 16: 1435\u20131440","journal-title":"Curr Biol"},{"key":"BFEMBR201845728_CR32","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1242\/dev.102392","volume":"141","author":"F Tie","year":"2014","unstructured":"Tie F, Banerjee R, Saiakhova AR, Howard B, Monteith KE, Scacheri PC, Cosgrove MS, Harte PJ (2014) Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing. Development 141: 1129\u20131139","journal-title":"Development"},{"key":"BFEMBR201845728_CR33","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.celrep.2014.05.002","volume":"7","author":"I Kronja","year":"2014","unstructured":"Kronja I, Yuan B, Eichhorn SW, Dzeyk K, Krijgsveld J, Bartel DP, Orr\u2010Weaver TL (2014) Widespread changes in the posttranscriptional landscape at the Drosophila oocyte\u2010to\u2010embryo transition. Cell Rep 7: 1495\u20131508","journal-title":"Cell Rep"},{"key":"BFEMBR201845728_CR34","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1186\/1471-2164-10-242","volume":"10","author":"DA Baker","year":"2009","unstructured":"Baker DA, Russell S (2009) Gene expression during Drosophila melanogaster egg development before and after reproductive diapause. BMC Genom 10: 242","journal-title":"BMC Genom"},{"key":"BFEMBR201845728_CR35","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1242\/dev.126.2.211","volume":"126","author":"K Kawamura","year":"1999","unstructured":"Kawamura K, Shibata T, Saget O, Peel D, Bryant PJ (1999) A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells. Development 126: 211\u2013219","journal-title":"Development"},{"key":"BFEMBR201845728_CR36","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S1534-5807(03)00337-X","volume":"5","author":"L Ringrose","year":"2003","unstructured":"Ringrose L, Rehmsmeier M, Dura J\u2010M, Paro R (2003) Genome\u2010wide prediction of Polycomb\/Trithorax response elements in Drosophila melanogaster. Dev Cell 5: 759\u2013771","journal-title":"Dev Cell"},{"key":"BFEMBR201845728_CR37","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1534\/genetics.116.199323","volume":"206","author":"SG Zimmerman","year":"2017","unstructured":"Zimmerman SG, Merrihew GE, MacCoss MJ, Berg CA (2017) Proteomics analysis identifies orthologs of human chitinase\u2010like proteins as inducers of tube morphogenesis defects in Drosophila melanogaster. Genetics 206: 973\u2013984","journal-title":"Genetics"},{"key":"BFEMBR201845728_CR38","doi-asserted-by":"crossref","first-page":"18340","DOI":"10.1038\/srep18340","volume":"6","author":"Y\u2010Y Pesch","year":"2016","unstructured":"Pesch Y\u2010Y, Riedel D, Patil KR, Loch G, Behr M (2016) Chitinases and Imaginal disc growth factors organize the extracellular matrix formation at barrier tissues in insects. Sci Rep 6: 18340","journal-title":"Sci Rep"},{"key":"BFEMBR201845728_CR39","doi-asserted-by":"crossref","first-page":"43273","DOI":"10.1038\/srep43273","volume":"7","author":"V Broz","year":"2017","unstructured":"Broz V, Kucerova L, Rouhova L, Fleischmannova J, Strnad H, Bryant PJ, Zurovec M (2017) Drosophila imaginal disc growth factor 2 is a trophic factor involved in energy balance, detoxification, and innate immunity. Sci Rep 7: 43273","journal-title":"Sci Rep"},{"key":"BFEMBR201845728_CR40","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1159\/000442351","volume":"8","author":"L Kucerova","year":"2016","unstructured":"Kucerova L, Broz V, Arefin B, Maaroufi HO, Hurychova J, Strnad H, Zurovec M, Theopold U (2016) The Drosophila chitinase\u2010like protein IDGF3 is involved in protection against nematodes and in wound healing. J Innate Immun 8: 199\u2013210","journal-title":"J Innate Immun"},{"key":"BFEMBR201845728_CR41","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1016\/j.biochi.2012.04.018","volume":"94","author":"A Sawicka","year":"2012","unstructured":"Sawicka A, Seiser C (2012) Histone H3 phosphorylation \u2013 a versatile chromatin modification for different occasions. Biochimie 94: 2193\u20132201","journal-title":"Biochimie"},{"key":"BFEMBR201845728_CR42","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1534\/genetics.111.126995","volume":"188","author":"HJ Bellen","year":"2011","unstructured":"Bellen HJ, Levis RW, He Y, Carlson JW, Evans\u2010Holm M, Bae E, Kim J, Metaxakis A, Savakis C, Schulze KL et al (2011) The Drosophila gene disruption project: progress using transposons with distinctive site specificities. Genetics 188: 731\u2013743","journal-title":"Genetics"},{"key":"BFEMBR201845728_CR43","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/B978-0-12-416024-8.00010-6","volume":"102","author":"AR Krauchunas","year":"2013","unstructured":"Krauchunas AR, Wolfner MF (2013) Molecular changes during egg activation. Curr Top Dev Biol 102: 267\u2013292","journal-title":"Curr Top Dev Biol"},{"key":"BFEMBR201845728_CR44","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/bs.ctdb.2015.06.004","volume":"113","author":"P Svoboda","year":"2015","unstructured":"Svoboda P, Franke V, Schultz RM (2015) Sculpting the transcriptome during the oocyte\u2010to\u2010embryo transition in mouse. Curr Top Dev Biol 113: 305\u2013349","journal-title":"Curr Top Dev Biol"},{"key":"BFEMBR201845728_CR45","doi-asserted-by":"crossref","first-page":"16061","DOI":"10.1073\/pnas.1315204110","volume":"110","author":"BJ Lesch","year":"2013","unstructured":"Lesch BJ, Dokshin GA, Young RA, McCarrey JR, Page DC (2013) A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis. Proc Natl Acad Sci USA 110: 16061\u201316066","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBR201845728_CR46","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1242\/dev.113027","volume":"141","author":"BJ Lesch","year":"2014","unstructured":"Lesch BJ, Page DC (2014) Poised chromatin in the mammalian germ line. Development 141: 3619\u20133626","journal-title":"Development"},{"key":"BFEMBR201845728_CR47","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.molcel.2017.04.018","volume":"66","author":"KM Dorighi","year":"2017","unstructured":"Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD, Garcia BA, Adelman K, Wysocka J (2017) Mll3 and Mll4 facilitate enhancer RNA synthesis and transcription from promoters independently of H3K4 monomethylation. Mol Cell 66: 568\u2013576.e4","journal-title":"Mol Cell"},{"key":"BFEMBR201845728_CR48","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/s41588-017-0015-6","volume":"50","author":"A Local","year":"2018","unstructured":"Local A, Huang H, Albuquerque CP, Singh N, Lee AY, Wang W, Wang C, Hsia JE, Shiau AK, Ge K et al (2018) Identification of H3K4me1\u2010associated proteins at mammalian enhancers. Nat Genet 50: 73\u201382","journal-title":"Nat Genet"},{"key":"BFEMBR201845728_CR49","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.stem.2017.03.003","volume":"21","author":"E H\u00f6rmanseder","year":"2017","unstructured":"H\u00f6rmanseder E, Simeone A, Allen GE, Bradshaw CR, Figlm\u00fcller M, Gurdon J, Jullien J (2017) H3K4 methylation\u2010dependent memory of somatic cell identity inhibits reprogramming and development of nuclear transfer embryos. Cell Stem Cell 21: 135\u2013143.e136","journal-title":"Cell Stem Cell"},{"key":"BFEMBR201845728_CR50","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1530\/rep.0.1230355","volume":"123","author":"WC Buhi","year":"2002","unstructured":"Buhi WC (2002) Characterization and biological roles of oviduct\u2010specific, oestrogen\u2010dependent glycoprotein. Reproduction 123: 355\u2013362","journal-title":"Reproduction"},{"key":"BFEMBR201845728_CR51","doi-asserted-by":"crossref","first-page":"3957","DOI":"10.1016\/j.celrep.2017.11.111","volume":"21","author":"Y Gao","year":"2017","unstructured":"Gao Y, Liu X, Tang B, Li C, Kou Z, Li L, Liu W, Wu Y, Kou X, Li J et al (2017) Protein expression landscape of mouse embryos during pre\u2010implantation development. Cell Rep 21: 3957\u20133969","journal-title":"Cell Rep"},{"key":"BFEMBR201845728_CR52","doi-asserted-by":"crossref","first-page":"e0123003","DOI":"10.1371\/journal.pone.0123003","volume":"10","author":"X Yang","year":"2015","unstructured":"Yang X, Zhao Y, Yang X, Kan FWK (2015) Recombinant hamster oviductin is biologically active and exerts positive effects on sperm functions and sperm\u2010oocyte binding. PLoS One 10: e0123003","journal-title":"PLoS One"},{"key":"BFEMBR201845728_CR53","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1002\/j.1939-4640.1994.tb00482.x","volume":"15","author":"RS King","year":"1994","unstructured":"King RS, Anderson SH, Killian GJ (1994) Effect of bovine oviductal estrus\u2010associated protein on the ability of sperm to capacitate and fertilize oocytes. J Androl 15: 468\u2013478","journal-title":"J Androl"},{"key":"BFEMBR201845728_CR54","doi-asserted-by":"crossref","first-page":"15809","DOI":"10.1073\/pnas.0804422105","volume":"105","author":"P Coy","year":"2008","unstructured":"Coy P, C\u00e1novas S, Mond\u00e9jar I, Saavedra MD, Romar R, Grull\u00f3n L, Mat\u00e1s C, Avil\u00e9s M (2008) Oviduct\u2010specific glycoprotein and heparin modulate sperm\u2010zona pellucida interaction during fertilization and contribute to the control of polyspermy. Proc Natl Acad Sci USA 105: 15809\u201315814","journal-title":"Proc Natl Acad Sci USA"},{"key":"BFEMBR201845728_CR55","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.anireprosci.2004.04.028","volume":"82\u201383","author":"GJ Killian","year":"2004","unstructured":"Killian GJ (2004) Evidence for the role of oviduct secretions in sperm function, fertilization and embryo development. Anim Reprod Sci 82\u201383: 141\u2013153","journal-title":"Anim Reprod Sci"},{"key":"BFEMBR201845728_CR56","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/(SICI)1521-1878(199909)21:9<718::AID-BIES2>3.0.CO;2-Z","volume":"21","author":"DR Hipfner","year":"1999","unstructured":"Hipfner DR, Cohen SM (1999) New growth factors for imaginal discs. BioEssays 21: 718\u2013720","journal-title":"BioEssays"},{"key":"BFEMBR201845728_CR57","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1530\/jrf.0.1130323","volume":"113","author":"NS Martus","year":"1998","unstructured":"Martus NS, Verhage HG, Mavrogianis PA, Thibodeaux JK (1998) Enhancement of bovine oocyte fertilization in vitro with a bovine oviductal specific glycoprotein. J Reprod Fertil 113: 323\u2013329","journal-title":"J Reprod Fertil"},{"key":"BFEMBR201845728_CR58","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1095\/biolreprod63.1.242","volume":"63","author":"AJ Kouba","year":"2000","unstructured":"Kouba AJ, Abeydeera LR, Alvarez IM, Day BN, Buhi WC (2000) Effects of the porcine oviduct\u2010specific glycoprotein on fertilization, polyspermy, and embryonic development in vitro. Biol Reprod 63: 242\u2013250","journal-title":"Biol Reprod"},{"key":"BFEMBR201845728_CR59","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1242\/dev.118.2.401","volume":"118","author":"AH Brand","year":"1993","unstructured":"Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401\u2013415","journal-title":"Development"},{"key":"BFEMBR201845728_CR60","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/nmeth.1592","volume":"8","author":"J\u2010Q Ni","year":"2011","unstructured":"Ni J\u2010Q, Zhou R, Czech B, Liu L\u2010P, Holderbaum L, Yang\u2010Zhou D, Shim H\u2010S, Tao R, Handler D, Karpowicz P et al (2011) A genome\u2010scale shRNA resource for transgenic RNAi in Drosophila. Nat Methods 8: 405\u2013407","journal-title":"Nat Methods"},{"key":"BFEMBR201845728_CR61","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0960-9822(98)70091-0","volume":"8","author":"M Van Doren","year":"1998","unstructured":"Van Doren M, Williamson AL, Lehmann R (1998) Regulation of zygotic gene expression in Drosophila primordial germ cells. Curr Biol 8: 243\u2013246","journal-title":"Curr Biol"},{"key":"BFEMBR201845728_CR62","doi-asserted-by":"crossref","first-page":"11","DOI":"10.4161\/spmg.19088","volume":"2","author":"H White\u2010Cooper","year":"2012","unstructured":"White\u2010Cooper H (2012) Tissue, cell type and stage\u2010specific ectopic gene expression and RNAi induction in the Drosophila testis. Spermatogenesis 2: 11\u201322","journal-title":"Spermatogenesis"},{"key":"BFEMBR201845728_CR63","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1093\/genetics\/131.3.643","volume":"131","author":"TB Chou","year":"1992","unstructured":"Chou TB, Perrimon N (1992) Use of a yeast site\u2010specific recombinase to produce female germline chimeras in Drosophila. Genetics 131: 643\u2013653","journal-title":"Genetics"},{"key":"BFEMBR201845728_CR64","first-page":"e1458","volume":"5","author":"P Prud\u00eancio","year":"2015","unstructured":"Prud\u00eancio P, Guilgur L (2015) FLP\/FRT induction of mitotic recombination in Drosophila germline. Bio\u2010Protocol 5: e1458","journal-title":"Bio\u2010Protocol"},{"key":"BFEMBR201845728_CR65","doi-asserted-by":"crossref","first-page":"e02181","DOI":"10.7554\/eLife.02181","volume":"3","author":"LG Guilgur","year":"2014","unstructured":"Guilgur LG, Prud\u00eancio P, Sobral D, Liszekova D, Rosa A, Martinho RG (2014) Requirement for highly efficient pre\u2010mRNA splicing during Drosophila early embryonic development. eLife 3: e02181","journal-title":"eLife"},{"key":"BFEMBR201845728_CR66","doi-asserted-by":"crossref","first-page":"39118","DOI":"10.1038\/srep39118","volume":"6","author":"AL Ribeiro","year":"2016","unstructured":"Ribeiro AL, Silva RD, Foyn H, Tiago MN, Rathore OS, Arnesen T, Martinho RG (2016) Naa50\/San\u2010dependent N\u2010terminal acetylation of Scc1 is potentially important for sister chromatid cohesion. Sci Rep 6: 39118","journal-title":"Sci Rep"},{"key":"BFEMBR201845728_CR67","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ydbio.2008.10.003","volume":"325","author":"WD Gilliland","year":"2009","unstructured":"Gilliland WD, Hughes SF, Vietti DR, Hawley RS (2009) Congression of achiasmate chromosomes to the metaphase plate in Drosophila melanogaster oocytes. Dev Biol 325: 122\u2013128","journal-title":"Dev Biol"},{"key":"BFEMBR201845728_CR68","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real\u2010time quantitative PCR and the 2(\u2010Delta Delta C(T)) Method. Methods 25: 402\u2013408","journal-title":"Methods"},{"key":"BFEMBR201845728_CR69","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nprot.2006.27","volume":"1","author":"JD Nelson","year":"2006","unstructured":"Nelson JD, Denisenko O, Bomsztyk K (2006) Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 1: 179\u2013185","journal-title":"Nat Protoc"},{"key":"BFEMBR201845728_CR70","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1186\/1471-2164-12-507","volume":"12","author":"MA Kallio","year":"2011","unstructured":"Kallio MA, Tuimala JT, Hupponen T, Klemel\u00e4 P, Gentile M, Scheinin I, Koski M, K\u00e4ki J, Korpelainen EI (2011) Chipster: user\u2010friendly analysis software for microarray and other high\u2010throughput data. BMC Genom 12: 507","journal-title":"BMC Genom"},{"key":"BFEMBR201845728_CR71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2202\/1544-6115.1027","volume":"3","author":"GK Smyth","year":"2004","unstructured":"Smyth GK (2004) Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: 1\u201325","journal-title":"Stat Appl Genet Mol Biol"},{"key":"BFEMBR201845728_CR72","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.chom.2015.11.002","volume":"18","author":"S Tripathi","year":"2015","unstructured":"Tripathi S, Pohl MO, Zhou Y, Rodriguez\u2010Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LCF et al (2015) Meta\u2010 and orthogonal integration of influenza \u2018OMICs\u2019 data defines a role for UBR4 in virus budding. Cell Host Microbe 18: 723\u2013735","journal-title":"Cell Host Microbe"},{"key":"BFEMBR201845728_CR73","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","volume":"30","author":"R Edgar","year":"2002","unstructured":"Edgar R, Domrachev M, Lash AE (2002) Gene expression omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30: 207\u2013210","journal-title":"Nucleic Acids Res"},{"key":"BFEMBR201845728_CR74","volume-title":"Ovarian development in Drosophila melanogaster","author":"RC King","year":"1970","unstructured":"King RC (1970) Ovarian development in Drosophila melanogaster. Amsterdam, The Netherlands: Academic Press"}],"container-title":["The EMBO Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.15252\/embr.201845728.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.15252\/embr.201845728","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.15252\/embr.201845728\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.embopress.org\/doi\/pdf\/10.15252\/embr.201845728","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.15252\/embr.201845728.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:25:35Z","timestamp":1779110735000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.15252\/embr.201845728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,23]]},"references-count":74,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8,1]]}},"alternative-id":["BFEMBR201845728"],"URL":"https:\/\/doi.org\/10.15252\/embr.201845728","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/242008","asserted-by":"object"}]},"ISSN":["1469-221X","1469-3178"],"issn-type":[{"value":"1469-221X","type":"print"},{"value":"1469-3178","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,23]]},"assertion":[{"value":"6 January 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 June 2018","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2018","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2018","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare that they have no conflict of interest.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"EMBR201845728"}}