{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T17:35:00Z","timestamp":1789580100665,"version":"build-2803163510"},"reference-count":40,"publisher":"Korean Society for Stem Cell Research","issue":"4","license":[{"start":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:00:00Z","timestamp":1693353600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2021M3E5D9021368"],"award-info":[{"award-number":["NRF-2021M3E5D9021368"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2019M3E5D2A01063939"],"award-info":[{"award-number":["NRF-2019M3E5D2A01063939"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2015M3C7A1028790"],"award-info":[{"award-number":["2015M3C7A1028790"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["NRF-2021M3E5D9021368"],"award-info":[{"award-number":["NRF-2021M3E5D9021368"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["NRF-2019M3E5D2A01063939"],"award-info":[{"award-number":["NRF-2019M3E5D2A01063939"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2015M3C7A1028790"],"award-info":[{"award-number":["2015M3C7A1028790"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["IITP-2023-2020-0-01819"],"award-info":[{"award-number":["IITP-2023-2020-0-01819"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.ijstemcell.com"],"crossmark-restriction":true},"short-container-title":["Int J Stem Cells"],"published-print":{"date-parts":[[2023,11,30]]},"DOI":"10.15283\/ijsc23012","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:02:43Z","timestamp":1693353763000},"page":"385-393","update-policy":"https:\/\/doi.org\/10.15283\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Transcriptional Signature of Valproic Acid-Induced Neural Tube Defects in Human Spinal Cord Organoids"],"prefix":"10.15283","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1006-7482","authenticated-orcid":false,"given":"Ju-Hyun","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Anatomy, Brain Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3675-4598","authenticated-orcid":false,"given":"Mohammed R.","family":"Shaker","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Brain Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4419-759X","authenticated-orcid":false,"given":"Si-Hyung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Brain Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1792-4894","authenticated-orcid":false,"given":"Woong","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Brain Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5946","published-online":{"date-parts":[[2023,8,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.109.2.243"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1181"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.1144"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70110-8"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/bdr2.1380"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20676"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.659612"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp347"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.7"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000129"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9926(199801)57:1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-007-0251-y"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-022-00868-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/BF02990416"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/19768354.2017.1324522"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq537"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420450208"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.mod.2017.12.001"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.14348\/molcells.2019.0162"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.15283\/ijsc22004"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.14348\/molcells.2022.2019"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.15283\/ijsc22006"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0237-5"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04026-9"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001100"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.37549"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.888152"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1603529113"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax5933"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1124\/mol.111.072314"},{"key":"ref31","unstructured":"Wegner C, Nau H. Alteration of embryonic folate metabolism by valproic acid during organogenesis: implications for mechanism of teratogenesis. Neurology 1992;42(4 Suppl 5):17-24."},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1093\/biohorizons\/hzt003"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.15283\/ijsc20213"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1080\/19768354.2020.1860126"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1002\/tcm.1770120503"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21847"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6101609"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16915"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1515\/biol-2022-0504"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.052102nb"}],"container-title":["International Journal of Stem Cells"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pdf.medrang.co.kr\/Ijsc2\/2023\/016\/Ijsc016-04-385.pdf","content-type":"unspecified","content-version":"tdm","intended-application":"text-mining"},{"URL":"https:\/\/pdf.medrang.co.kr\/Ijsc2\/2023\/016\/Ijsc016-04-385.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T06:36:35Z","timestamp":1723012595000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.ijstemcell.com\/journal\/view.html?doi=10.15283\/ijsc23012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,30]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11,30]]}},"alternative-id":["10.15283\/ijsc23012"],"URL":"https:\/\/doi.org\/10.15283\/ijsc23012","relation":{},"ISSN":["2005-5447"],"issn-type":[{"value":"2005-5447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,30]]},"assertion":[{"value":"http:\/\/www.ijstemcell.com\/journal\/view.html?doi=10.15283\/ijsc23012","URL":"http:\/\/www.ijstemcell.com\/journal\/view.html?doi=10.15283\/ijsc23012","name":"the_journal","label":"International Journal of Stem Cells","group":{"name":"multiple_resolution","label":"Full text available at:"}},{"value":"2023-02-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-30","order":3,"name":"published","label":"Online First","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-30","order":4,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}},{"value":"\u00a9 2023 The Korean Society for Stem Cell Research","name":"copyright","label":"Copyright","group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","explanation":{"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},"group":{"name":"Copyright_and_licensing","label":"Copyright and Licensing"}}]}}