{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T22:30:57Z","timestamp":1648852257000},"reference-count":9,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":2145,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biophysical Journal"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1529\/biophysj.107.114561","type":"journal-article","created":{"date-parts":[[2007,7,14]],"date-time":"2007-07-14T00:43:28Z","timestamp":1184373808000},"page":"L32-L34","source":"Crossref","is-referenced-by-count":6,"title":["The S631A Mutation Causes a Mechanistic Switch in the Block of hERG Channels by CnErg1"],"prefix":"10.1016","volume":"93","author":[{"given":"Adam P.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.J.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.S.","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.W.","family":"Kuchel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.I.","family":"Vandenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1529\/biophysj.107.114561_bib1","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.toxicon.2004.03.024","article-title":"Toxin determinants required for interaction with voltage-gated K+ channels","volume":"43","author":"Jouirou","year":"2004","journal-title":"Toxicon"},{"key":"10.1529\/biophysj.107.114561_bib2","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/S0006-3495(93)81200-1","article-title":"Mechanism of charybdotoxin block of a voltage-gated K+ channel","volume":"65","author":"Goldstein","year":"1993","journal-title":"Biophys. J."},{"key":"10.1529\/biophysj.107.114561_bib3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/jmr.667","article-title":"Unique interaction of scorpion toxins with the hERG channel","volume":"17","author":"Korolkova","year":"2004","journal-title":"J. Mol. Recogn."},{"key":"10.1529\/biophysj.107.114561_bib4","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1529\/biophysj.106.101956","article-title":"Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1","volume":"92","author":"Hill","year":"2007","journal-title":"Biophys. J."},{"key":"10.1529\/biophysj.107.114561_bib5","doi-asserted-by":"crossref","first-page":"16403","DOI":"10.1074\/jbc.M200460200","article-title":"Mapping the binding site of a human ether-\u00e1-Go-Go-related gene-specific peptide toxin (ErgTx) to the channel\u2019s outer vestibule","volume":"277","author":"Pardo-Lopez","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1529\/biophysj.107.114561_bib6","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1113\/jphysiol.2006.108332","article-title":"Effect of S5P \u03b1-helix charge mutants on inactivation of hERG K+ channels","volume":"573","author":"Clarke","year":"2006","journal-title":"J. Physiol."},{"key":"10.1529\/biophysj.107.114561_bib7","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0896-6273(00)80057-4","article-title":"Agitoxin footprinting the Shaker potassium channel pore","volume":"16","author":"Gross","year":"1996","journal-title":"Neuron"},{"key":"10.1529\/biophysj.107.114561_bib8","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0014-5793(03)00216-3","article-title":"Solution structure of CnErg1 (Ergtoxin), a HERG-specific scorpion toxin","volume":"539","author":"Torres","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1529\/biophysj.107.114561_bib9","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0165-6147(03)00223-2","article-title":"Turret and pore block of K+ channels: what is the difference?","volume":"24","author":"Xu","year":"2003","journal-title":"Trends Pharmacol. Sci."}],"container-title":["Biophysical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006349507714406?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006349507714406?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,6]],"date-time":"2019-01-06T04:20:03Z","timestamp":1546748403000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006349507714406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0006349507714406"],"URL":"https:\/\/doi.org\/10.1529\/biophysj.107.114561","relation":{},"ISSN":["0006-3495"],"issn-type":[{"value":"0006-3495","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}