{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T06:34:20Z","timestamp":1785220460678,"version":"3.55.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1964,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>The effects of oral administration of synthetic progestins on the urinary oestrogen excretion were examined. 17\u03b1-ethynyl-19-nortestosterone (ENT) or 17\u03b1-ethynyl-estr-4-en-17\u03b2-ol (EEL) caused a significant rise of oestrogen output in urine. It appeared that the increased output of oestrogen was due to the conversion of ENT or EEL to ethynyl-oestradiol (EE2). Such a conversion of progestin was also observed with 17\u03b1-methyl-19-nortestosterone.<\/jats:p>\n        <jats:p>To obtain the direct evidence for the conversion of ENT to EE2, human placental homogenates were incubated <jats:italic>in vitro<\/jats:italic> first with 19-nortestosterone. The approximate yield of oestrone was 20 percent of that observed with testosterone. However, a conversion of ENT to EE2 was not detected.<\/jats:p>","DOI":"10.1530\/acta.0.0460031","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:29:45Z","timestamp":1229372985000},"page":"31-36","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":17,"title":["CONVERSION OF SOME SYNTHETIC PROGESTINS TO OESTROGEN"],"prefix":"10.1093","volume":"46","author":[{"given":"Hiroji","family":"Okada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Amatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadanao","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gen-ichi","family":"Tokuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/46\/1\/acta_46_1_004.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/46\/1\/acta_46_1_004.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:23:33Z","timestamp":1676391813000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/46\/1\/31\/6890247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1964,5]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0460031","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1964,5]]}}}