{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T05:24:11Z","timestamp":1676438651834},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1966,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>Hypopituitarism may present with a functional and reversible contraction of skeletal muscle which involves primarily the flexor and adductor muscles of the thighs. Two further cases demonstrating this association are described and discussed.<\/jats:p>\n        <jats:p>It appears that the flexor spasm is consequent upon a failure in cortisol production following pituitary or adrenal damage.<\/jats:p>\n        <jats:p>It is suggested that the syndrome follows the internal shift in water and electrolytes with disturbed sodium transport which occurs in cortisol deficiency. This may act through a direct effect on muscle contractility or on neuromuscular transmission. The possibility remains that this effect is not seen until the blood glucose level falls, and that the hypoglycaemia is not merely an associated feature.<\/jats:p>","DOI":"10.1530\/acta.0.0530489","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:29:45Z","timestamp":1229372985000},"page":"489-498","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":1,"title":["HYPOPITUITARISM AND FLEXOR MUSCLE SPASM"],"prefix":"10.1093","volume":"53","author":[{"given":"A. G.","family":"Stewart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. G.","family":"Sprunt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/53\/3\/acta_53_3_016.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/53\/3\/acta_53_3_016.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:27:44Z","timestamp":1676392064000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/53\/3\/489\/6890809"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,11]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0530489","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1966,11]]}}}