{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:06:08Z","timestamp":1761955568555,"version":"build-2065373602"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1967,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>Whole peripheral venous blood from normal men and women, and from females with idiopathic hirsutism was incubated <jats:italic>in vitro<\/jats:italic> with labelled testosterone, androstenedione and dehydro<jats:italic>epi<\/jats:italic>androsterone. <jats:italic>Epi<\/jats:italic>testosterone was formed consistently from added testosterone, in some cases from androstenedione but not from dehydro<jats:italic>epi<\/jats:italic>androsterone. The rate of formation of <jats:italic>epi<\/jats:italic>testosterone from testosterone by blood of normal men and women is similar, whereas the rate of formation in blood from female idiopathic hirsutes was several fold greater. In a similar manner, normal human adrenal tissue also formed <jats:italic>epi<\/jats:italic>testosterone from added testosterone but not from androstenedione nor dehydro<jats:italic>epi<\/jats:italic>androsterone. These results suggest that the origin of urinary <jats:italic>epi<\/jats:italic>testosterone can be the resultant of both peripheral production and endocrine gland secretion.<\/jats:p>","DOI":"10.1530\/acta.0.0540208","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:59:13Z","timestamp":1229374753000},"page":"208-214","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":11,"title":["FORMATION OF EPITESTOSTERONE BY HUMAN BLOOD AND ADRENAL TISSUE"],"prefix":"10.1093","volume":"54","author":[{"given":"Jorge","family":"Blaquier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph I.","family":"Dorfman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Forchielli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/54\/2\/acta_54_2_002.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/54\/2\/acta_54_2_002.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:28:01Z","timestamp":1676392081000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/54\/2\/208\/6894021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1967,2]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0540208","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"type":"print","value":"0804-4643"},{"type":"electronic","value":"1479-683X"}],"subject":[],"published":{"date-parts":[[1967,2]]}}}