{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:27:16Z","timestamp":1759541236116},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1968,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>Three patients with so-called localized pretibial myxoedema were studied. The serum titre of LATS activity and the contents of iodo-amino acids were determined. One patient who simultaneously developed a diffuse toxic goitre and pretibial myxoedema showed a high titre of LATS. The second patient who developed pretibial myxoedema showed no LATS activity. This patient probably had a recurrence of Graves' disease in a nodular goitre. The third patient who developed pretibial myxoedema a few years after thyroidectomy for diffuse toxic goitre possibly had a low titre of LATS. The serum contents of iodo-amino acids were increased in cases 1 and 2. The analysis was unsuccessful in case 3.<\/jats:p>\n        <jats:p>The significance of the findings is briefly discussed. It is concluded that the development of pretibial myxoedema is not correlated with the occurrence of LATS.<\/jats:p>","DOI":"10.1530\/acta.0.0590409","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:59:13Z","timestamp":1229374753000},"page":"409-416","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":1,"title":["LONG ACTING THYROID STIMULATOR (LATS) AND IODO-AMINO ACIDS IN LOCALIZED PRETIBIAL MYXOEDEMA"],"prefix":"10.1093","volume":"59","author":[{"given":"Sven-M\u00e5rten","family":"Samuelsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivar","family":"Werner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/59\/3\/acta_59_3_007.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/59\/3\/acta_59_3_007.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:31:16Z","timestamp":1676392276000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/59\/3\/409\/6894360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1968,11]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0590409","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1968,11]]}}}