{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:02:08Z","timestamp":1770822128832,"version":"3.50.1"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1970,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>The authors studied the gonads of 20 children presenting different types of pseudohermaphroditism with the object of comparing the histological findings with those observed in cases of simple cryptorchidism. The picture seen in:<\/jats:p>\n        <jats:p><jats:list list-type=\"alpha-lower\"><jats:list-item><jats:p>Miscellaneous male pseudohermaphroditism is identical to that of simple cryptorchidism.<\/jats:p><\/jats:list-item> <jats:list-item><jats:p>The feminizing testicular syndrome shows a distinct difference from that seen in the undescended testis of children of the same age. There is proliferation of spindle cells resembling ovarian stroma, but with no follicular derivatives. After puberty there is a discrepancy between the presence of large groups of Leydig cells and an immaturity of the seminiferous tubules.<\/jats:p><\/jats:list-item> <jats:list-item><jats:p>The testicular lesion in mixed gonadal dysgenesis resembles that of cryptorchidism. However, serial sectioning of entire streaks allowed the demonstration in 3 cases of a tumour entirely composed of germinal cells. In one of these cases a biopsy taken one year previously had revealed no abnormalities. The tumour somewhat resembles a gonadoblastoma but with a difference. No previous reference to such a tumour in children at puberty has been found. Similar lesions were seen in the opposite testicle in two cases. In the light of these findings, it is considered that in such cases the streak and also the testicle should be completely removed to avoid a possible later development of a generalised seminoma.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p>","DOI":"10.1530\/acta.0.0640211","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:59:13Z","timestamp":1229374753000},"page":"211-227","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":16,"title":["GONADAL HISTOLOGY IN CHILDREN WITH MALE PSEUDOHERMAPHRODITISM AND MIXED GONADAL DYSGENESIS"],"prefix":"10.1093","volume":"64","author":[{"given":"B.","family":"Salle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chr.","family":"Hedinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/64\/2\/acta_64_2_002.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/64\/2\/acta_64_2_002.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:11:02Z","timestamp":1676391062000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/64\/2\/211\/6893885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,6]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0640211","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,6]]}}}