{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:37:26Z","timestamp":1759541846020},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1970,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n        <jats:p>Serum thyroxine (T<jats:sub>4<\/jats:sub>) and other thyroid function tests were studied in 14 patients with subacute thyroiditis and compared with the same parameters in 32 patients with untreated thyrotoxicosis. The mean values of serum T<jats:sub>4<\/jats:sub> and protein-bound iodine (PBI) were found to be elevated to the same extent in the two groups and the calculated T<jats:sub>4<\/jats:sub> iodine did not differ significantly from the PBI in any of the groups. The resin-T<jats:sub>3<\/jats:sub>-test and the basal metabolic rate (BMR) mean values were significantly lower in patients with subacute thyroiditis than in patients with thyrotoxicosis. The serum T<jats:sub>4<\/jats:sub> determination based on competitive protein-binding was not influenced by other organic iodinated products, and our results indicate that the elevated serum PBI in subacute thyroiditis is largely due to T<jats:sub>4<\/jats:sub>. The lower BMR in patients with subacute thyroiditis is possibly explained by a difference in the thyroxine binding protein (TBP) binding capacity and free T<jats:sub>4<\/jats:sub> in the serum between patients with subacute thyroiditis and those with thyrotoxicosis.<\/jats:p>","DOI":"10.1530\/acta.0.0640359","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T20:59:13Z","timestamp":1229374753000},"page":"359-363","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":3,"title":["SERUM THYROXINE IN THE EARLY PHASE OF SUBACUTE THYROIDITIS"],"prefix":"10.1093","volume":"64","author":[{"given":"N. J. B.","family":"Christiansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Siersb\u00e6k-Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. E.M.","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Korsgaard","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/64\/2\/acta_64_2_013.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/64\/2\/acta_64_2_013.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:11:08Z","timestamp":1676391068000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/64\/2\/359\/6893876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,6]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0640359","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,6]]}}}