{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T10:15:57Z","timestamp":1699697757139},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1976,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n<jats:p>During late pregnancy the urinary excretion of steroid 21-deoxyketols, which contain the CH<jats:sub>3<\/jats:sub>-CO-C(OH)&lt; side chain, was 1.16 \u00b1 0.50 mg\/24 h (mean \u00b1 <jats:sc>sd<\/jats:sc> n = 9). The mean excretion of these metabolites in 8 pregnancies with an anencephalic foetus showed a significant reduction (<jats:italic>P<\/jats:italic> &lt; 0.01, <jats:italic>t<\/jats:italic>-test) to 0.42 \u00b1 0.18 mg\/24 h. Six untreated non-pregnant women and 7 taking oral contraceptives which contain oestrogen had steroid 21-deoxyketol excretions of 0.26 \u00b1 0.09 mg\/24 h and 0.19 \u00b1 0.09 mg\/24 h respectively.<\/jats:p>\n<jats:p>These results imply that the adrenal of the normal foetus makes a contribution to the secretion of those steroids which are ultimately excreted by the mother as 21-deoxyketols.<\/jats:p>","DOI":"10.1530\/acta.0.0810598","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:31:09Z","timestamp":1229376669000},"page":"598-604","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":1,"title":["DIFFERENCES IN URINARY EXCRETION OF STEROID 21-DEOXYKETOLS BY WOMEN PREGNANT WITH A NORMAL OR AN ANENCEPHALIC FOETUS"],"prefix":"10.1093","volume":"81","author":[{"given":"C. A.","family":"Adejuwon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. F.","family":"Heys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. E.","family":"Oakey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/81\/3\/acta_81_3_004.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/81\/3\/acta_81_3_004.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:27:17Z","timestamp":1676392037000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/81\/3\/598\/6839214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,3]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0810598","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,3]]}}}