{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:54:33Z","timestamp":1758477273212},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1978,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n<jats:p>Fat cell size and lipid composition of subcutaneous tissue from 3 patients with congenital generalized lipodystrophy have been measured before and after treatment with either pimozide, fenfluramine or hypophysectomy. The fat cell volume before treatment ranged between 9.8 \u00d7 10<jats:sup>4<\/jats:sup> and 17.7 \u00d7 10<jats:sup>4<\/jats:sup> \u03bcm<jats:sup>3<\/jats:sup>, compared to 9.0 \u00d710<jats:sup>4<\/jats:sup> and 85.3 \u00d7 10<jats:sup>4<\/jats:sup> \u03bcm<jats:sup>3<\/jats:sup> in 15 controls. The amount of lipids was only 1\/10 to 1\/50 of normal, triglycerides being the most heavily reduced lipid component.<\/jats:p>\n<jats:p>Neither the fat cell size nor the lipid content were affected by treatment with hypophysectomy, pimozide or fenfluramine.<\/jats:p>","DOI":"10.1530\/acta.0.0880182","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:31:09Z","timestamp":1229376669000},"page":"182-189","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":5,"title":["FAT CELL SIZE AND LIPID CONTENT OF SUBCUTANEOUS TISSUE IN CONGENITAL GENERALIZED LIPODYSTROPHY"],"prefix":"10.1093","volume":"88","author":[{"given":"Torleiv Ole","family":"Rognum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian S.","family":"Bjerve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Seip","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olav","family":"Trygstad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Svein","family":"Oseid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/88\/1\/acta_88_1_023.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/88\/1\/acta_88_1_023.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:30:34Z","timestamp":1676392234000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/88\/1\/182\/6802828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,5]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.0880182","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,5]]}}}