{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T13:59:20Z","timestamp":1697810360047},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,8]]},"abstract":"<jats:title>Abstract.<\/jats:title>\n<jats:p>Experiments were designed to investigate the effect of \u03b1-adrenergic stimulation on parathyroid hormone (PTH) responses to isoproterenol (ISO). In addition, PTH responses to adrenaline (A) and hypocalcaemia were studied with and without \u03b1-adrenergic blockade by phentolamine. Infusions of phenylephrine (a 'pure' \u03b1-adrenergic agonist) did not modify basal PTH levels and PTH responses to ISO infusions, whereas the heart rate response to ISO was reduced (<jats:italic>P<\/jats:italic> &lt; 0.05). The results demonstrate that \u03b1-adrenergic stimulation by phenylephrine does not reduce PTH responses to \u03b2-adrenergic agonists. In response to phentolamine the heart rate increased and plasma levels of Ca and Ca++ decreased. Plasma PTH concentrations were slightly but not significantly raised and PTH responses to adrenaline (<jats:italic>P<\/jats:italic> &lt; 0.05), but not to hypocalcaemia, were enhanced. The potentiation of PTH responses to A in the presence of phentolamine may have been due to inhibition of \u03b1-adrenergic properties of A. It may have been also, in part, the consequence of the hypocalcaemia, which is known to augment PTH responses to A.<\/jats:p>","DOI":"10.1530\/acta.0.1000539","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:36:12Z","timestamp":1229376972000},"page":"539-542","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":2,"title":["Effects of \u03b1-adrenergic stimulation and blockade on parathyroid hormone responses to \u03b2-adrenergic agonists in cattle"],"prefix":"10.1093","volume":"100","author":[{"given":"J. W.","family":"Blum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. A.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Binswanger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/100\/4\/acta_100_4_010.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/100\/4\/acta_100_4_010.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:13:52Z","timestamp":1676391232000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/100\/4\/539\/6802822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,8]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.1000539","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,8]]}}}