{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:01:22Z","timestamp":1697760082846},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,9]]},"abstract":"<jats:title>Abstract.<\/jats:title>\n<jats:p>Prl responsiveness to TRH and sulpiride was evaluated in 14 galactorrhoeic normoprolactinaemic women. Radiological signs of sellar alteration were present in 6 of these patients. Pituitary responses to TRH did not differ from those obtained in a group of 16 healthy women. Serum Prl levels after sulpiride were higher in the patients than in the controls (<jats:italic>P<\/jats:italic>&lt;0.01). The Amax response was 256 \u00b1 16 <jats:sc>SE<\/jats:sc> vs 158 \u00b1 10.6 ng\/ml in the control group (<jats:italic>P<\/jats:italic>&lt;0.01). The mean integrated area after sulpiride was also greater (20738 \u00b1 1263 <jats:sc>se<\/jats:sc> ng\/ml\/2 h vs 13 188 \u00b1 408) (<jats:italic>P<\/jats:italic>&lt; 0.01).<\/jats:p>\n<jats:p>The markedly enhanced Prl response to sulpiride in our patients with galactorrhoea could be due to a functional disorder of the hypothalamic-pituitary axis or to a lactotrope hyperplasia.<\/jats:p>","DOI":"10.1530\/acta.0.1010001","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:36:12Z","timestamp":1229376972000},"page":"1-4","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":4,"title":["Dynamics of Prl release in galactorrhoeic normoprolactinaemic women"],"prefix":"10.1093","volume":"101","author":[{"given":"R.","family":"D'Agata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Aliffi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Maugeri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mongio\u00ec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Vicari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Gulizia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/101\/1\/acta_101_1_001.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/101\/1\/acta_101_1_001.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:13:58Z","timestamp":1676391238000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/101\/1\/1\/6802454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,9]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.1010001","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,9]]}}}