{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T05:23:34Z","timestamp":1676438614321},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:title>Abstract.<\/jats:title>\n<jats:p>In the hepatic nucleus of the rat at least 2 nuclear globulin bands, identified by SDS polyacrylamide gel electrophoresis, are known to be influenced by thyroid hormones. In the present article a quantitation of these bands was obtained by scanning techniques. The effects of T<jats:sub>3<\/jats:sub> were studied in male thyroidectomized (Tx) and intact rats. After sacrifice the hepatic nuclear globulins were prepared according to published methods.<\/jats:p>\n<jats:p>In Tx rats substituted with a single dose of 50 \u03bcg or during one week 2 \u03bcg T<jats:sub>3<\/jats:sub> the t band decreased from 5.3% to 2.7% of the total nuclear globulin content which represent a complete normalisation.<\/jats:p>\n<jats:p>The n band did not show this rapid response to T<jats:sub>3<\/jats:sub> as 2 \u03bcg given for one week only partially restored this band (Tx 1.4%,Tx + T<jats:sub>3<\/jats:sub>2.2%).<\/jats:p>\n<jats:p>However during starvation of intact rats only the n band was slightly influenced by T<jats:sub>3<\/jats:sub> as 2 \u03bcg of T<jats:sub>3<\/jats:sub> partially prevented the decrease of this band seen in untreated euthyroid starving rats. The increase of the t band in starvation was not affected by T<jats:sub>3<\/jats:sub>.<\/jats:p>\n<jats:p>In conclusion: the n and t bands are controlled by several factors, two of which are T<jats:sub>3<\/jats:sub> and nutrition. The control of the t band seems to be dominated by the nutritional status of the animal. T<jats:sub>3<\/jats:sub> seems to keep some activity on the n band, even in starved rats.<\/jats:p>","DOI":"10.1530\/acta.0.1020567","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:53:47Z","timestamp":1229378027000},"page":"567-571","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":1,"title":["Effects of triiodothyronine and nutritional status on nuclear non-histone proteins of the rat liver"],"prefix":"10.1093","volume":"102","author":[{"given":"Cristiana E.","family":"Juge-Aubry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert G.","family":"Burger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/102\/4\/acta_102_4_017.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/102\/4\/acta_102_4_017.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:15:32Z","timestamp":1676391332000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/102\/4\/567\/6802588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.1020567","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,4]]}}}