{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T08:31:46Z","timestamp":1697963506153},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1983,11]]},"abstract":"<jats:p>Abstract. The binding capacity of the sex-hormone-binding globulin (SHBG) was determined by means of a new dihydrotestosterone-binding-capacity test in 73 pregnant women admitted to hospital because of vaginal bleeding between the 6th and 18th gestational week. In general, pregnancies ending in spontaneous abortion displayed lower SHBG-levels than pregnancies with a successful outcome, but a great deal of overlap in SHBG values was found between the abortive and the non-abortive cases. In the 6th to 9th weeks of pregnancy 'non-pregnant' SHBG levels were frequently found despite normal levels of oestradiol (E<jats:sub>2<\/jats:sub>) in patients continuing pregnancy until delivery. After the 9th gestational week a highly significant positive correlation was found between E<jats:sub>2<\/jats:sub> and SHBG. The lack of correlation between these parameters before this gestational age indicates that the increased SHBG synthesis seen in pregnancy develops later than the rise in E<jats:sub>2<\/jats:sub>. Determinations of SHBG were found to be of limited value in evaluation of the prognosis is threatened abortion.<\/jats:p>","DOI":"10.1530\/acta.0.1040381","type":"journal-article","created":{"date-parts":[[2008,12,15]],"date-time":"2008-12-15T21:53:47Z","timestamp":1229378027000},"page":"381-384","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":5,"title":["Sex-hormone-binding globulin (SHBG) in serum in threatened abortion"],"prefix":"10.1093","volume":"104","author":[{"given":"J. B.","family":"Hertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. G.","family":"Johnsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["Acta Endocrinologica"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/104\/3\/acta_104_3_020.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/104\/3\/acta_104_3_020.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:16:56Z","timestamp":1676391416000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/104\/3\/381\/6795719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,11]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/acta.0.1040381","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,11]]}}}