{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:16:23Z","timestamp":1784556983130,"version":"3.55.0"},"reference-count":0,"publisher":"Bioscientifica","issue":"1","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["ec.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>\n                    Neuroendocrine tumors (NETs) arising in the small intestine are known to produce vasoactive substances, including serotonin, that may result in the carcinoid syndrome (flushing, diarrhea, bronchoconstriction, and carcinoid heart disease). Measurement of the serotonin breakdown product 5-hydroxyindoleacetic acid (5-HIAA) in urine is important in diagnosing and monitoring of patients with intestinal NETs. Our aim was to compare 5-HIAA measurement in 24-h urine sampling with overnight (\u223c8-h) sampling in patients with known NETs, or at follow-up of patients potentially cured for their NETs. Twenty-four-hour and overnight urine samples were collected from 34 patients and analyzed for urinary 5-HIAA (U5-HIAA) using HPLC. Comparison of the overnight sampling values with the 24-h values showed no difference,\n                    <jats:italic>P<\/jats:italic>\n                    =0.45, and there was a significant direct correlation between the two samples using linear regression (\n                    <jats:italic>R<\/jats:italic>\n                    =0.97,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.001). U5-HIAA sample collection during a nightly interval of \u223c8\u200ah appears to have the same accuracy as the 24-h collection in this group of patients.\n                  <\/jats:p>","DOI":"10.1530\/ec-12-0077","type":"journal-article","created":{"date-parts":[[2012,12,17]],"date-time":"2012-12-17T23:03:15Z","timestamp":1355785395000},"page":"50-54","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-10","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of 24-h and overnight samples of urinary 5-hydroxyindoleacetic acid in patients with intestinal neuroendocrine tumors"],"prefix":"10.1530","volume":"2","author":[{"given":"Merete","family":"Gedde-Dahl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Espen","family":"Thiis-Evensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas Myklebust","family":"Tj\u00f8lsen","sequence":"additional","affiliation":[{"name":"Section of Gastroenterology Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Postboks 4953, Nydalen, 0424 Oslo, Norway 1 University of Oslo School of Medicine Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjerstin Skrede","family":"Mordal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Vatn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deidi S","family":"Bergestuen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Endocrine Connections"],"original-title":[],"link":[{"URL":"https:\/\/ec.bioscientifica.com\/view\/journals\/ec\/2\/1\/50.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ec.bioscientifica.com\/downloadpdf\/journals\/ec\/2\/1\/50.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:41:40Z","timestamp":1784554900000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.bioscientifica.com\/ec\/article\/2\/1\/50-54\/35050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1530\/ec-12-0077","relation":{},"ISSN":["2049-3614"],"issn-type":[{"value":"2049-3614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}