{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:07:36Z","timestamp":1788538056414,"version":"build-2803163510"},"reference-count":0,"publisher":"Bioscientifica","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ec.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:p>Embryo implantation is a complex process in which multiple molecules acting together under strict regulation. Studies showed the production of various adipokines and their receptors in the embryo and uterus, where they can influence the maternal-fetal transmission of metabolites and embryo implantation. Therefore, these cytokines have opened a novel area of study in the field of embryo\u2013maternal crosstalk during early pregnancy. In this respect, the involvement of adipokines has been widely reported in the regulation of both physiological and pathological aspects of the implantation process. However, the information about the role of some recently identified adipokines is limited. This review aims to highlight the role of various adipokines in embryo\u2013maternal interactions, endometrial receptivity, and embryo implantation, as well as the underlying molecular mechanisms.<\/jats:p>","DOI":"10.1530\/ec-21-0288","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T09:46:18Z","timestamp":1632476778000},"page":"R267-R278","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-10","source":"Crossref","is-referenced-by-count":11,"title":["Role of adipokines in embryo implantation"],"prefix":"10.1530","volume":"10","author":[{"given":"Davoud","family":"Jafari-Gharabaghlou","sequence":"first","affiliation":[{"name":"1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran"},{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mostafa","family":"Vaghari-Tabari","sequence":"additional","affiliation":[{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajar","family":"Oghbaei","sequence":"additional","affiliation":[{"name":"3Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lotz","sequence":"additional","affiliation":[{"name":"4Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen\u2013N\u00fcrnberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Zarezadeh","sequence":"additional","affiliation":[{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeganeh","family":"Rastgar Rezaei","sequence":"additional","affiliation":[{"name":"5Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahnaz","family":"Ranjkesh","sequence":"additional","affiliation":[{"name":"6Medical Radiation Science Research Group (MRSRG), Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Nouri","sequence":"additional","affiliation":[{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"},{"name":"7Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5712-5336","authenticated-orcid":true,"given":"Amir","family":"Fattahi","sequence":"additional","affiliation":[{"name":"4Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen\u2013N\u00fcrnberg, Erlangen, Germany"},{"name":"8Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saba","family":"Nikanfar","sequence":"additional","affiliation":[{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"},{"name":"2Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Dittrich","sequence":"additional","affiliation":[{"name":"4Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen\u2013N\u00fcrnberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","container-title":["Endocrine Connections"],"original-title":[],"link":[{"URL":"https:\/\/ec.bioscientifica.com\/view\/journals\/ec\/10\/11\/EC-21-0288.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ec.bioscientifica.com\/downloadpdf\/journals\/ec\/10\/11\/EC-21-0288.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:44:43Z","timestamp":1784555083000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.bioscientifica.com\/ec\/article\/10\/11\/R267-R278\/184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":0,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.1530\/ec-21-0288","relation":{},"ISSN":["2049-3614"],"issn-type":[{"value":"2049-3614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,1]]}}}