{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:52Z","timestamp":1784557072447,"version":"3.55.0"},"reference-count":33,"publisher":"Bioscientifica","issue":"12","license":[{"start":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T00:00:00Z","timestamp":1727395200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ec.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,9,27]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Evidence has demonstrated that visceral fat area (VFA) and subcutaneous fat area (SFA) have different influences on cardiovascular disease (CVD) risk in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate the relationship between the visceral fat area (VFA), the subcutaneous fat area (SFA) ratio (V\/S), and carotid atherosclerosis (CAS) in patients with T2DM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From January 2018 to May 2023, 1838 patients with T2DM admitted to the National Metabolic Management Centre in our hospital were assigned to two groups based on comorbid CAS. Dual bioelectrical impedance analysis was used to measure the VAF and SFA, and the V\/S was calculated. Patient characteristics and serum biochemical indices were compared between groups. Factors influencing comorbid CAS were determined, and correlations between V\/S and other clinical indices were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The group with comorbid CAS included 858 individuals and 980 without comorbid CAS. Those with comorbid CAS were older and had a longer disease duration, more significant systolic blood pressure, and greater V\/S. The proportions of patients with comorbid hypertension increased significantly with the V\/S ratio. The V\/S ratio positively correlated with triglyceride (TG), low-density lipoprotein cholesterol levels, and waist circumference. According to binary logistic regression analysis, V\/S was an independent risk factor for CAS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Elevated V\/S is an independent risk factor for CAS in patients with T2DM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/ec-24-0412","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T14:33:52Z","timestamp":1727447632000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-10","source":"Crossref","is-referenced-by-count":5,"title":["The visceral fat area\/subcutaneous fat area ratio is positively associated with carotid atherosclerosis in patients with type 2 diabetes mellitus"],"prefix":"10.1530","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9442-7592","authenticated-orcid":true,"given":"Dandan","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1975-7954","authenticated-orcid":true,"given":"Xiangguo","family":"Cong","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beibei","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0390-6832","authenticated-orcid":true,"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Diabetes Research and Clinical Practice","first-page":"109119","article-title":"IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045","volume":"183","author":"Sun","year":"2022","unstructured":"Sun HSaeedi PKaruranga SPinkepank MOgurtsova KDuncan BBStein CBasit AChan JCNMbanya JC, et al. IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Research and Clinical Practice 2022 183 109119. (https:\/\/doi.org\/10.1016\/j.diabres.2021.109119)"},{"key":"bib2","series-title":"Atherosclerosis","first-page":"50","article-title":"Obesity and incidence of diabetes: effect of absence of metabolic syndrome, insulin resistance, inflammation and fatty liver","volume":"275","author":"Sung","year":"2018","unstructured":"Sung KCLee MYKim YHHuh JHKim JYWild SH & Byrne CD. Obesity and incidence of diabetes: effect of absence of metabolic syndrome, insulin resistance, inflammation and fatty liver. Atherosclerosis 2018 275 50\u201357. (https:\/\/doi.org\/10.1016\/j.atherosclerosis.2018.05.042)"},{"key":"bib3","series-title":"BMJ Open Diabetes Research and Care","article-title":"Serum levels of mac-2 binding protein are associated with diabetic microangiopathy and macroangiopathy in people with type 2 diabetes","volume":"8","author":"Hashimoto","year":"2020","unstructured":"Hashimoto YHamaguchi MKaji ASakai RKitagawa N & Fukui M. Serum levels of mac-2 binding protein are associated with diabetic microangiopathy and macroangiopathy in people with type 2 diabetes. BMJ Open Diabetes Research and Care 2020 8. (https:\/\/doi.org\/10.1136\/bmjdrc-2020-001189)"},{"key":"bib4","series-title":"Expert Review of Gastroenterology and Hepatology","first-page":"3","article-title":"Obesity, diabetes, and the gut microbiome: an updated review","volume":"13","author":"Singer-Englar","year":"2019","unstructured":"Singer-Englar TBarlow G & Mathur R. Obesity, diabetes, and the gut microbiome: an updated review. Expert Review of Gastroenterology and Hepatology 2019 13 3\u201315. (https:\/\/doi.org\/10.1080\/17474124.2019.1543023)"},{"key":"bib5","series-title":"Lancet","first-page":"1640","article-title":"Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study","volume":"366","author":"Yusuf","year":"2005","unstructured":"Yusuf SHawken SOunpuu SBautista LFranzosi MGCommerford PLang CCRumboldt ZOnen CLLisheng L, et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 2005 366 1640\u20131649. (https:\/\/doi.org\/10.1016\/S0140-6736(05)67663-5)"},{"key":"bib6","series-title":"Diabetes Care","first-page":"1808","article-title":"Visceral adiposity and incident coronary heart disease in Japanese-American men. The 10-year follow-up results of the Seattle Japanese-American community diabetes study","volume":"22","author":"Fujimoto","year":"1999","unstructured":"Fujimoto WYBergstrom RWBoyko EJChen KWLeonetti DLNewell-Morris LShofer JB & Wahl PW. Visceral adiposity and incident coronary heart disease in Japanese-American men. The 10-year follow-up results of the Seattle Japanese-American community diabetes study. Diabetes Care 1999 22 1808\u20131812. (https:\/\/doi.org\/10.2337\/diacare.22.11.1808)"},{"key":"bib7","series-title":"Journal of the American College of Cardiology","first-page":"921","article-title":"Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality","volume":"62","author":"Britton","year":"2013","unstructured":"Britton KAMassaro JMMurabito JMKreger BEHoffmann U & Fox CS. Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality. Journal of the American College of Cardiology 2013 62 921\u2013925. (https:\/\/doi.org\/10.1016\/j.jacc.2013.06.027)"},{"key":"bib8","series-title":"International Journal of Obesity","first-page":"286","article-title":"Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity","volume":"36","author":"G\u00f3mez-Ambrosi","year":"2012","unstructured":"G\u00f3mez-Ambrosi JSilva CGalofr\u00e9 JCEscalada JSantos SMill\u00e1n DVila NIba\u00f1ez PGil MJValent\u00ed V, et al. Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity. International Journal of Obesity 2012 36 286\u2013294. (https:\/\/doi.org\/10.1038\/ijo.2011.100)"},{"key":"bib9","series-title":"International Journal of Obesity","first-page":"791","article-title":"Diagnostic performance of body mass index to identify obesity as defined by body adiposity: a systematic review and meta-analysis","volume":"34","author":"Okorodudu","year":"2010","unstructured":"Okorodudu DOJumean MFMontori VMRomero-Corral ASomers VKErwin PJ & Lopez-Jimenez F. Diagnostic performance of body mass index to identify obesity as defined by body adiposity: a systematic review and meta-analysis. International Journal of Obesity 2010 34 791\u2013799. (https:\/\/doi.org\/10.1038\/ijo.2010.5)"},{"key":"bib10","series-title":"Diabetes Care","first-page":"504","article-title":"Distribution of abdominal visceral and subcutaneous adipose tissue and metabolic syndrome in a Korean population","volume":"34","author":"Kim","year":"2011","unstructured":"Kim SCho BLee HChoi KHwang SSKim DKim K & Kwon H. Distribution of abdominal visceral and subcutaneous adipose tissue and metabolic syndrome in a Korean population. Diabetes Care 2011 34 504\u2013506. (https:\/\/doi.org\/10.2337\/dc10-1364)"},{"key":"bib11","series-title":"Diabetologia","first-page":"2622","article-title":"The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk","volume":"55","author":"Kaess","year":"2012","unstructured":"Kaess BMPedley AMassaro JMMurabito JHoffmann U & Fox CS. The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk. Diabetologia 2012 55 2622\u20132630. (https:\/\/doi.org\/10.1007\/s00125-012-2639-5)"},{"key":"bib12","series-title":"International Journal of Cardiology","first-page":"112","article-title":"Not visceral fat area but the ratio of visceral to subcutaneous fat area is significantly correlated with the marker for atherosclerosis in obese subjects","volume":"179","author":"Katsuyama","year":"2015","unstructured":"Katsuyama HKawaguchi A & Yanai H. Not visceral fat area but the ratio of visceral to subcutaneous fat area is significantly correlated with the marker for atherosclerosis in obese subjects. International Journal of Cardiology 2015 179 112\u2013113. (https:\/\/doi.org\/10.1016\/j.ijcard.2014.10.112)"},{"key":"bib13","series-title":"International Journal of Cardiology","first-page":"150","article-title":"Increased subcutaneous fat accumulation has a protective role against subclinical atherosclerosis in asymptomatic subjects undergoing general health screening","volume":"135","author":"Narumi","year":"2009","unstructured":"Narumi HYoshida KHashimoto NUmehara IFunabashi NYoshida S & Komuro I. Increased subcutaneous fat accumulation has a protective role against subclinical atherosclerosis in asymptomatic subjects undergoing general health screening. International Journal of Cardiology 2009 135 150\u2013155. (https:\/\/doi.org\/10.1016\/j.ijcard.2008.03.044)"},{"key":"bib14","series-title":"Journal of Diabetes Investigation","first-page":"396","article-title":"Ratio of visceral-to-subcutaneous fat area predicts cardiovascular events in patients with type 2 diabetes","volume":"9","author":"Fukuda","year":"2018","unstructured":"Fukuda TBouchi RTakeuchi TNakano YMurakami MMinami IIzumiyama HHashimoto KYoshimoto T & Ogawa Y. Ratio of visceral-to-subcutaneous fat area predicts cardiovascular events in patients with type 2 diabetes. Journal of Diabetes Investigation 2018 9 396\u2013402. (https:\/\/doi.org\/10.1111\/jdi.12713)"},{"issue":"Supplement 1","key":"bib15","series-title":"Diabetes Care","first-page":"S1","article-title":"American Diabetes Association. Introduction: the American diabetes association's (ADA) evidence-based practice guidelines, standards, and related recommendations and documents for diabetes care","volume":"35","year":"2012","unstructured":"American Diabetes Association. Introduction: the American diabetes association's (ADA) evidence-based practice guidelines, standards, and related recommendations and documents for diabetes care. Diabetes Care 2012 35(Supplement 1) S1\u2013S2. (https:\/\/doi.org\/10.2337\/dc12-s001)"},{"key":"bib16","series-title":"Arteriosclerosis, Thrombosis, and Vascular Biology","first-page":"1045","article-title":"Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: a case-control study","volume":"25","author":"Brea","year":"2005","unstructured":"Brea AMosquera DMart\u00edn EArizti ACordero JL & Ros E. Nonalcoholic fatty liver disease is associated with carotid atherosclerosis: a case-control study. Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 1045\u20131050. (https:\/\/doi.org\/10.1161\/01.ATV.0000160613.57985.18)"},{"key":"bib17","series-title":"World Journal of Gastroenterology","first-page":"1848","article-title":"Hepatic steatosis is associated with an increased risk of carotid atherosclerosis","volume":"11","author":"Volzke","year":"2005","unstructured":"Volzke HRobinson DMKleine VDeutscher RHoffmann WLudemann JSchminke UKessler C & John U. Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. World Journal of Gastroenterology 2005 11 1848\u20131853. (https:\/\/doi.org\/10.3748\/wjg.v11.i12.1848)"},{"key":"bib18","series-title":"World Journal of Gastroenterology","first-page":"4770","article-title":"Carotid lesions in outpatients with nonalcoholic fatty liver disease","volume":"15","author":"Ramilli","year":"2009","unstructured":"Ramilli SPretolani SMuscari APacelli B & Arienti V. Carotid lesions in outpatients with nonalcoholic fatty liver disease. World Journal of Gastroenterology 2009 15 4770\u20134774. (https:\/\/doi.org\/10.3748\/wjg.15.4770)"},{"key":"bib19","series-title":"Circulation","first-page":"32","article-title":"Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the cardiovascular health study","volume":"116","author":"Cao","year":"2007","unstructured":"Cao JJArnold AMManolio TAPolak JFPsaty BMHirsch CHKuller LH & Cushman M. Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the cardiovascular health study. Circulation 2007 116 32\u201338. (https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.106.645606)"},{"key":"bib20","series-title":"Diabetes Care","first-page":"1937","article-title":"Carotid plaque calcification predicts future cardiovascular events in type 2 diabetes","volume":"38","author":"Vigili de Kreutzenberg","year":"2015","unstructured":"Vigili de Kreutzenberg SFadini GPGuzzinati SMazzucato MVolpi ACoracina A & Avogaro A. Carotid plaque calcification predicts future cardiovascular events in type 2 diabetes. Diabetes Care 2015 38 1937\u20131944. (https:\/\/doi.org\/10.2337\/dc15-0327)"},{"key":"bib21","series-title":"Circulation","first-page":"e674","article-title":"The heart of 25 by 25: achieving the goal of reducing global and regional premature deaths from cardiovascular diseases and stroke: a modeling study from the American Heart Association and World Heart Federation","volume":"133","author":"Sacco","year":"2016","unstructured":"Sacco RLRoth GAReddy KSArnett DKBonita RGaziano TAHeidenreich PAHuffman MDMayosi BMMendis S, et al. The heart of 25 by 25: achieving the goal of reducing global and regional premature deaths from cardiovascular diseases and stroke: a modeling study from the American Heart Association and World Heart Federation. Circulation 2016 133 e674\u2013e690. (https:\/\/doi.org\/10.1161\/CIR.0000000000000395)"},{"key":"bib22","series-title":"Lancet","first-page":"29","article-title":"Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study","volume":"368","author":"Booth","year":"2006","unstructured":"Booth GLKapral MKFung K & Tu JV. Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet 2006 368 29\u201336. (https:\/\/doi.org\/10.1016\/S0140-6736(06)68967-8)"},{"key":"bib23","series-title":"Diabetologia","first-page":"301","article-title":"Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The health ABC study","volume":"48","author":"Snijder","year":"2005","unstructured":"Snijder MBVisser MDekker JMGoodpaster BHHarris TBKritchevsky SBDe Rekeneire NKanaya AMNewman ABTylavsky FA, et al. Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The health ABC study. Diabetologia 2005 48 301\u2013308. (https:\/\/doi.org\/10.1007\/s00125-004-1637-7)"},{"key":"bib24","series-title":"Diabetes Care","first-page":"1068","article-title":"Abdominal subcutaneous adipose tissue: a protective fat depot?","volume":"32","author":"Porter","year":"2009","unstructured":"Porter SAMassaro JMHoffmann UVasan RSO'Donnel CJ & Fox CS. Abdominal subcutaneous adipose tissue: a protective fat depot? Diabetes Care 2009 32 1068\u20131075. (https:\/\/doi.org\/10.2337\/dc08-2280)"},{"key":"bib25","series-title":"New England Journal of Medicine","first-page":"2549","article-title":"Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease","volume":"350","author":"Klein","year":"2004","unstructured":"Klein SFontana LYoung VLCoggan ARKilo CPatterson BW & Mohammed BS. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. New England Journal of Medicine 2004 350 2549\u20132557. (https:\/\/doi.org\/10.1056\/NEJMoa033179)"},{"key":"bib26","series-title":"British Journal of Plastic Surgery","first-page":"190","article-title":"Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women","volume":"57","author":"Giugliano","year":"2004","unstructured":"Giugliano GNicoletti GGrella EGiugliano FEsposito KScuderi N & D'Andrea F. Effect of liposuction on insulin resistance and vascular inflammatory markers in obese women. British Journal of Plastic Surgery 2004 57 190\u2013194. (https:\/\/doi.org\/10.1016\/j.bjps.2003.12.010)"},{"key":"bib27","series-title":"American Journal of Pathology","first-page":"1474","article-title":"Biological relevance of inflammation and oxidative stress in the pathogenesis of arterial diseases","volume":"182","author":"Hajjar","year":"2013","unstructured":"Hajjar DP & Gotto AMJr. Biological relevance of inflammation and oxidative stress in the pathogenesis of arterial diseases. American Journal of Pathology 2013 182 1474\u20131481. (https:\/\/doi.org\/10.1016\/j.ajpath.2013.01.010)"},{"key":"bib28","series-title":"Nature","first-page":"875","article-title":"Mechanisms linking obesity with cardiovascular disease","volume":"444","author":"Van Gaal","year":"2006","unstructured":"Van Gaal LFMertens IL & De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006 444 875\u2013880. (https:\/\/doi.org\/10.1038\/nature05487)"},{"key":"bib29","series-title":"Nutrition Journal","first-page":"4","article-title":"Relationship of adiposity and insulin resistance mediated by inflammation in a group of overweight and obese Chilean adolescents","volume":"10","author":"Reyes","year":"2011","unstructured":"Reyes MGahagan SD\u00edaz EBlanco ELeiva LLera L & Burrows R. Relationship of adiposity and insulin resistance mediated by inflammation in a group of overweight and obese Chilean adolescents. Nutrition Journal 2011 10 4. (https:\/\/doi.org\/10.1186\/1475-2891-10-4)"},{"key":"bib30","series-title":"Clinical Immunology","first-page":"157","article-title":"The role of resistin as a regulator of inflammation: implications for various human pathologies","volume":"133","author":"Filkov\u00e1","year":"2009","unstructured":"Filkov\u00e1 MHaluz\u00edk MGay S & Senolt L. The role of resistin as a regulator of inflammation: implications for various human pathologies. Clinical Immunology 2009 133 157\u2013170. (https:\/\/doi.org\/10.1016\/j.clim.2009.07.013)"},{"key":"bib31","series-title":"Arquivos Brasileiros de Cardiologia","first-page":"261","article-title":"Body mass index has a good correlation with proatherosclerotic profile in children and adolescents","volume":"93","author":"Costa","year":"2009","unstructured":"Costa GBHorta NResende ZFSouza GBarreto LMFCorreia LHNascimento TARios CBBarreto-Filho JA & Lopes HF. Body mass index has a good correlation with proatherosclerotic profile in children and adolescents. Arquivos Brasileiros de Cardiologia 2009 93 261\u2013267. (https:\/\/doi.org\/10.1590\/s0066-782x2009001000003)"},{"key":"bib32","series-title":"Diabetologia","first-page":"1371","article-title":"Leptin: its role in obesity and beyond","volume":"40","author":"Tritos","year":"1997","unstructured":"Tritos NA & Mantzoros CS. Leptin: its role in obesity and beyond. Diabetologia 1997 40 1371\u20131379. (https:\/\/doi.org\/10.1007\/s001250050838)"},{"key":"bib33","series-title":"Diabetologia","first-page":"1127","article-title":"Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?","volume":"50","author":"Yang","year":"2007","unstructured":"Yang X & Smith U. Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer? Diabetologia 2007 50 1127\u20131139. 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