{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T03:54:37Z","timestamp":1791431677776,"version":"4.3.3"},"reference-count":142,"publisher":"Bioscientifica","issue":"6","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":256,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Middle\/Young aged Teachers' Research Ability Improvement Project of Guangxi Higher Education","award":["2024KY0099"],"award-info":[{"award-number":["2024KY0099"]}]},{"name":"Guangxi Natural Science Foundation","award":["2025GXNSFAA069050"],"award-info":[{"award-number":["2025GXNSFAA069050"]}]},{"name":"Young Medical Reserve Talent Training Program of Guangxi province"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Polycystic ovary syndrome (PCOS), a prevalent reproductive endocrine and metabolic disorder in gynecology, has hyperandrogenism (HA) as an essential pathophysiological alteration. PCOS patients, with or without HA, present diverse clinical manifestations. The function of intestinal or reproductive tract microorganisms in PCOS has drawn attention in recent years and is associated with the occurrence of HA. In this article, we review the connection between the microbial alterations in the intestinal and reproductive tracts and androgens in PCOS, and elaborate on the role of TLRs in this process.<\/jats:p>","DOI":"10.1530\/ec-25-0162","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T12:14:19Z","timestamp":1748952859000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-10","source":"Crossref","is-referenced-by-count":2,"title":["The role of microbiota and toll-like receptors in polycystic ovary syndrome: regulatory mechanisms of androgen metabolism"],"prefix":"10.1530","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6066-3380","authenticated-orcid":true,"given":"Xueming","family":"Huang","sequence":"first","affiliation":[{"name":"Guangxi Medical University , , ,","place":["Nanning, Guangxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuyan","family":"Wu","sequence":"additional","affiliation":[{"name":"Guangxi Medical University , , ,","place":["Nanning, Guangxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangxi Medical University , , ,","place":["Nanning, Guangxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowen","family":"Lai","sequence":"additional","affiliation":[{"name":"Guangxi Medical University , , ,","place":["Nanning, Guangxi, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Sun","sequence":"additional","affiliation":[{"name":"Guangxi Medical University , , ,","place":["Nanning, Guangxi, 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