{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T21:24:20Z","timestamp":1784928260045,"version":"3.55.0"},"reference-count":32,"publisher":"Bioscientifica","content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,7,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Background: Spontaneous ovarian hyperstimulation syndrome (sOHSS) can occur following hypothyroidism. Ultrasonography facilitates diagnosis and monitoring of this syndrome. We describe ovarian sonographic changes in a hypothyroid patient with sOHSS after treatment with levothyroxine (\n                    <jats:sc>l<\/jats:sc>\n                    -T\n                    <jats:sub>4<\/jats:sub>\n                    ).\n                  <\/jats:p>\n                  <jats:p>\n                    Case presentation: A 15-year-old girl presented with abdominal pain and distension for a few months. On examination, she had classical features of hypothyroidism. Abdominal and pelvic ultrasound revealed enlarged ovaries with multiple thin-walled cysts and mild ascitic fluid. On follow-up, abdominal ultrasound showed significant reduction of ovary size after 6 weeks of initiation of\n                    <jats:sc>l<\/jats:sc>\n                    -T\n                    <jats:sub>4<\/jats:sub>\n                    . Normal ovary size with complete regression of ovarian cysts was seen after 4 months.\n                  <\/jats:p>\n                  <jats:p>Conclusion: Serial ultrasound in sOHSS associated with hypothyroidism showed regression of ovarian cysts and ovarian volume after 4 months whereas in other studies, it is reported to happen in various durations, presumably according to its etiology.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Learning points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>OHSS can rarely occur due to hypothyroidism.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            This type of OHSS can be simply treated by\n                            <jats:sc>l<\/jats:sc>\n                            -T\n                            <jats:sub>4<\/jats:sub>\n                            replacement, rather than conservative management or surgery in severe cases.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Ultrasound follow-up shows significant regression of ovarian size and cysts within 6 weeks of initiation of\n                            <jats:sc>l<\/jats:sc>\n                            -T\n                            <jats:sub>4<\/jats:sub>\n                            .\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Ultrasound follow-up shows normal ovarian size with complete resolution of ovarian cysts 4 months after treatment.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/edm-13-0006","type":"journal-article","created":{"date-parts":[[2013,7,4]],"date-time":"2013-07-04T10:38:04Z","timestamp":1372934284000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":11,"title":["Ovarian cyst regression with levothyroxine in ovarian hyperstimulation syndrome associated with hypothyroidism"],"prefix":"10.1530","volume":"2013","author":[{"given":"Roghieh","family":"Molaei Langroudi","sequence":"first","affiliation":[{"name":"Diagnostic Radiology DepartmentPoursina Hospital, Guilan University of Medical Sciences, Guilan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Ghazanfari Amlashi","sequence":"additional","affiliation":[{"name":"1Guilan Endocrinology and Metabolism Research CenterRazi Hospital, Rasht, Guilan, Iran and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hassan","family":"Hedayati Emami","sequence":"additional","affiliation":[{"name":"2Department of EndocrinologyGuilan Endocrinology and Metabolism Research Center, Razi Hospital, Rasht, Guilan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"ref221","first-page":"39","article-title":"CordasoCOlodeNSoaresL Spontaneous ovarian hyperstimulation and primary hypothyroidism with a naturally conceived pregnancy and","year":"1999","journal-title":"Obstetrics Gynecology"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1385\/ENDO:26:3:285","article-title":"Understanding ovarian hyperstimulation syndrome","volume":"26","year":"2005","journal-title":"Endocrine"},{"key":"ref191","first-page":"575","article-title":"SH Abdominal pelvic thoracic sonography gynecology Ultrasound th ch CM Philadelphia","volume":"15","author":"Salem","year":"2011","journal-title":"edn"},{"key":"ref31","first-page":"575","article-title":"SH 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