{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:16:38Z","timestamp":1784556998596,"version":"3.55.0"},"reference-count":8,"publisher":"Bioscientifica","content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,10,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Until now, less than ten cases of extra-adrenal chromaffin cell tumors have been reported to be localized to the spermatic cord area. All published studies report benign tumors with a diameter &lt;2\u20133\u200acm and no invasion of the testis. In this article, we present one case of a giant malignant paraganglioma in the testis of a patient who had initially been operated for a giant mass in the scrotum. The mass developed in approximately 4 months. This is the first study reporting the following findings: i) paraganglioma was found exclusively in the testis, invading the testicle and not the spermatic cord, ii) it was malignant with lung metastasis, and iii) its size was 17.5\u200acm\u00d710\u200acm\u00d79.5\u200acm. We present the first \u2013 giant \u2013 malignant paraganglioma. Moreover, it is the first case report of a paraganglioma in the testis.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Learning points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>This is the first study reporting the following findings:<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Paraganglioma found exclusively in the testis, invading the testicle and not the spermatic cord.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>It is malignant with lung metastasis.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>It is of the size 17.5\u200acm\u00d710\u200acm\u00d79.5\u200acm.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/edm-14-0055","type":"journal-article","created":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T03:49:20Z","timestamp":1414468160000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":1,"title":["A \u2018giant\u2019 paraganglioma in the testis"],"prefix":"10.1530","volume":"2014","author":[{"given":"Marinos C","family":"Makris","sequence":"first","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"},{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos C","family":"Koumarelas","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apostolos S","family":"Mitrousias","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giannos G","family":"Psathas","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Mantzioros","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stratigoula P","family":"Sakellariou","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiota","family":"Ntailiani","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evripides","family":"Yettimis","sequence":"additional","affiliation":[{"name":"1 First Surgical Department of General Hospital of Athens \u2018Georgios Gennimatas\u2019, Mesogeion 154, Athens 15669, Greece 2 Alpha Institute of Biomedical Sciences (AIBS), Marousi, Athens, Greece 3 Department of Pathology, Medical School, University of Athens, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"ref71","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1100\/tsw.2008.161","article-title":"Paraganglioma of the spermatic cord: case report and review of the literature","volume":"8","year":"2008","journal-title":"Scientific World Journal"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"811","DOI":"10.5858\/133.5.811","article-title":"Paratesticular paraganglioma: a rare cause of an intrascrotal mass","volume":"133","year":"2009","journal-title":"Archives of Pathology & Laboratory Medicine"},{"key":"ref61","first-page":"2411","article-title":"of testis ch th PC AB ED Philadelphia","author":"Richie","year":"1998","journal-title":"Urology 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