{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:29:23Z","timestamp":1792524563346,"version":"4.5.0"},"reference-count":30,"publisher":"Bioscientifica","content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,2,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Functional parathyroid cysts are a rare cause of primary hyperparathyroidism and are often mistaken for thyroid cysts. Systemic lupus erythematosus (SLE) is also a very rare cause of hypercalcemia. We report the case of a 62-year-old woman, who was diagnosed with SLE 30 years ago, presenting with clinical and biochemical features of primary hyperparathyroidism. Laboratory investigation revealed increased serum calcium and parathyroid hormone (PTH) levels; neck ultrasonography (USG) revealed 40\u00d734\u00d726\u200amm cystic mass in the left lobe of thyroid gland. PTH level in the cysts was &gt;2500\u200apg\/ml, determined by USG-guided fine-needle aspiration (FNA). In this case, no evidence for potential pathogenic association between parathyroid cyst and SLE was uncovered. However, the recognition of this association is very important because the therapeutical strategy is completely different. Operative management is usually straightforward and alleviates symptoms and any biochemical abnormalities caused by the cyst.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Learning points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Functional parathyroid cysts are the rare cause of primary hyperparathyroidism and are often mistaken for thyroid cysts.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>SLE is also a very rare cause of hypercalcemia.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Ultrasound-guided FNA of cystic fluid with assay for PTH level is an accurate method of differentiating parathyroid cyst from thyroid cyst.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Appropriate management of functional parathyroid cysts is surgical excision.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/edm-14-0100","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T04:48:26Z","timestamp":1423025306000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":7,"title":["Functional parathyroid cyst in a patient with systemic lupus erythematosus: a case report"],"prefix":"10.1530","volume":"2015","author":[{"given":"Jingjing","family":"Jiang","sequence":"first","affiliation":[{"name":"1 Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronghua","family":"He","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiping","family":"Shen","sequence":"additional","affiliation":[{"name":"2 Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"3 Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"ref31","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0002-9610(82)90198-2","article-title":"Parathyroid cysts","volume":"143","year":"1982","journal-title":"American Journal of Surgery"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1017\/S0022215100143208","article-title":"Parathyroid cyst: a rare cause of an anterior neck mass","volume":"113","year":"1999","journal-title":"Journal of Laryngology and Otology"},{"key":"ref221","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1507\/endocrj.50.215","article-title":"Functional giant parathyroid cyst with high concentration of CA19-9 in cystic fluid","volume":"50","year":"2003","journal-title":"Endocrine 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