{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:31Z","timestamp":1784557051019,"version":"3.55.0"},"reference-count":10,"publisher":"Bioscientifica","content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,6,8]]},"abstract":"Summary<\/jats:title>\n Solitary sellar plasmacytomas are exceedingly rare and difficult to distinguish from other pituitary tumors. We report a case of a 62-year-old woman presenting with blurred vision of the right eye and tenderness of the right temporal region, which was interpreted as temporal arteritis. MRI revealed a pituitary mass lesion (20mm\u00d714mm\u00d717mm) without compression of the optic chiasm and her pituitary function was normal. Pituitary surgery was undertaken due to growth of the lesion, and histopathological examination showed a highly cellular neoplasm composed of mature monoclonal plasma cells. Subsequent examinations revealed no evidence of extrasellar myeloma. The patient received pituitary irradiation and has remained well and free of symptoms apart from iatrogenic central diabetes insipidus. Until now, only eight cases of solitary sellar plasmacytoma have been reported. Most frequent symptoms stem from compression of the cranial nerves in the cavernous sinus (III, IV, V), whereas the anterior pituitary function is mostly intact.<\/jats:p>\n \n Learning points<\/jats:title>\n \n \n \n A solitary plasmacytoma is a rare cause of a sellar mass lesion.<\/jats:p>\n <\/jats:list-item>\n \n The radiological and clinical features are nonspecific, but cranial nerve affection and intact pituitary function are usually present.<\/jats:p>\n <\/jats:list-item>\n \n The diagnosis is made histologically and has important therapeutic implications.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1530\/edm-16-0031","type":"journal-article","created":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T06:38:13Z","timestamp":1465281493000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":6,"title":["The solitary sellar plasmacytoma: a diagnostic challenge"],"prefix":"10.1530","volume":"2016","author":[{"given":"Anne","family":"Soejbjerg","sequence":"first","affiliation":[{"name":"1Department of Internal Medicine, Silkeborg Regional Hospital, Silkeborg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzan","family":"Dyve","sequence":"additional","affiliation":[{"name":"2Department of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steen","family":"Baerentzen","sequence":"additional","affiliation":[{"name":"3Department of Pathology, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Thorsell","sequence":"additional","affiliation":[{"name":"4Department of Hematology, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per L","family":"Poulsen","sequence":"additional","affiliation":[{"name":"5Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens O L","family":"Jorgensen","sequence":"additional","affiliation":[{"name":"5Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Kampmann","sequence":"additional","affiliation":[{"name":"5Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"key20160610151751432_bib1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1046\/j.1365-2141.2003.04355.x","article-title":"Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Group","volume":"121","author":"The International Myeloma Working Group","year":"2003","journal-title":"British Journal of Haematology"},{"key":"key20160610151751432_bib2","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1097\/MD.0000000000000058","article-title":"Sellar solitary plasmacytoma progressing to multiple myeloma: a case report and literature review","volume":"93","author":"Jiang","year":"2014","journal-title":"Medicine"},{"key":"key20160610151751432_bib3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s11102-011-0352-x","article-title":"Sellar plasmacytomas: a concise review","volume":"15","author":"Joukhader","year":"2012","journal-title":"Pituitary"},{"key":"key20160610151751432_bib4","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1007\/s00701-008-0012-8","article-title":"Intrasellar plasmacytoma: an unusual presentation of multiple myeloma","volume":"150","author":"Yaman","year":"2008","journal-title":"Acta Neurochirurgica"},{"key":"key20160610151751432_bib5","doi-asserted-by":"crossref","first-page":"bcr0320126050","DOI":"10.1136\/bcr-03-2012-6050","article-title":"Metastatic haematological malignancy presenting as a sellar mass","volume":"2012","author":"Udiawar M","year":"2012","journal-title":"BMJ Case Reports"},{"key":"key20160610151751432_bib6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11102-006-8281-9","article-title":"Intrasellar plasmacytoma presenting as a non-functional invasive pituitary macro-adenoma: a case report & literature review","volume":"9","author":"Sinnot","year":"2006","journal-title":"Pituitary"},{"key":"key20160610151751432_bib7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jocn.2011.07.009","article-title":"Intrasellar plasmacytoma: an illustrative case and literature review","volume":"19","author":"Kahn","year":"2012","journal-title":"Journal of Clinical Neuroscience"},{"key":"key20160610151751432_bib8","doi-asserted-by":"crossref","first-page":"iii47","DOI":"10.1136\/jnnp.2004.045740","article-title":"Pituitary disease: presentation, diagnosis and management","volume":"75","author":"Levy","year":"2004","journal-title":"Journal of Neurology, Neurosurgery, and Psychiatry"},{"key":"key20160610151751432_bib9","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1365-2141.2004.04834.x","article-title":"Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma","volume":"124","author":"Soutar","year":"2004","journal-title":"British Journal of Haematology"},{"key":"key20160610151751432_bib10","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1038\/leu.2009.134","article-title":"Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic\/racial groups: support for genetic factors in pathogenesis","volume":"23","author":"Landgren","year":"2009","journal-title":"Leukemia"}],"container-title":["Endocrinology, Diabetes & Metabolism Case Reports"],"original-title":[],"link":[{"URL":"https:\/\/edm.bioscientifica.com\/view\/journals\/edm\/2016\/1\/EDM16-0031.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/edm.bioscientifica.com\/downloadpdf\/journals\/edm\/2016\/1\/EDM16-0031.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:46:18Z","timestamp":1784555178000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.bioscientifica.com\/edm\/article\/3216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,8]]},"references-count":10,"URL":"https:\/\/doi.org\/10.1530\/edm-16-0031","relation":{},"ISSN":["2052-0573"],"issn-type":[{"value":"2052-0573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,8]]}}}