{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:16:30Z","timestamp":1789186590706,"version":"build-2803163510"},"reference-count":40,"publisher":"Bioscientifica","license":[{"start":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T00:00:00Z","timestamp":1519344000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/deed.en_GB"}],"content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,2,23]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    A 26-year-old woman presented with severe postpartum headaches. Magnetic resonance imaging (MRI) revealed a symmetric, heterogeneous enlargement of the pituitary gland. Three months later, she developed central diabetes insipidus. A diagnosis of postpartum hypophysitis was suspected and corticosteroids were prescribed. Six months later, the pituitary mass showed further enlargement and characteristics of a necrotic abscess with a peripheral shell and infiltration of the hypothalamus. Transsphenoidal surgery was performed, disclosing a pus-filled cavity which was drained. No bacterial growth was observed, except a single positive blood culture for\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    , considered at that time as a potential contaminant. A short antibiotic course was, however, administered together with hormonal substitution for panhypopituitarism. Four months after her discharge, severe headaches recurred. Pituitary MRI was suggestive of a persistent inflammatory mass of the sellar region. She underwent a new transsphenoidal resection of a residual abscess. At that time, the sellar aspiration fluid was positive for\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    and she was treated with antibiotics for 6 weeks, after which she had complete resolution of her infection. The possibility of a pituitary abscess, although rare, should be kept in mind during evaluation for a necrotic inflammatory pituitary mass with severe headaches and hormonal deficiencies.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Learning points:<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>The possibility of a pituitary abscess, although rare, should be kept in mind during evaluation for a necrotic inflammatory pituitary mass with severe headaches and hormonal deficiencies.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>In a significant proportion of cases no pathogenic organism can be isolated.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>A close follow-up is necessary given the risk of recurrence and the high rate of postoperative pituitary deficiencies.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>","DOI":"10.1530\/edm-17-0162","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T08:50:10Z","timestamp":1519375810000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":6,"title":["Recurrent pituitary abscess: case report and review of the literature"],"prefix":"10.1530","volume":"2018","author":[{"given":"Raluca Maria","family":"Furnica","sequence":"first","affiliation":[{"name":"1Departments of Endocrinology, Pathology, and NeuroradiologyUniversit\u00e9 catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Lelotte","sequence":"additional","affiliation":[{"name":"2Departments of Pathology, and NeuroradiologyUniversit\u00e9 catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Duprez","sequence":"additional","affiliation":[{"name":"3Departments of NeuroradiologyUniversit\u00e9 catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Maiter","sequence":"additional","affiliation":[{"name":"1Departments of Endocrinology, Pathology, and NeuroradiologyUniversit\u00e9 catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orsalia","family":"Alexopoulou","sequence":"additional","affiliation":[{"name":"1Departments of Endocrinology, Pathology, and NeuroradiologyUniversit\u00e9 catholique de Louvain, Cliniques Universitaires Saint-Luc, Brussels, 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