{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:26Z","timestamp":1784557046123,"version":"3.55.0"},"reference-count":10,"publisher":"Bioscientifica","issue":"3","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7,1]]},"abstract":"\n Summary<\/jats:title>\n The etiology of foot drop is diverse from various diseases to mechanic injuries and includes neuropathy of the peroneal nerve. Peroneal neuropathy might also be one of the forms of diabetic neuropathy, very rarely reported as the first sign of diabetes. We describe three cases of children with newly diagnosed type 1 diabetes (TID) who developed unilateral peroneal nerve palsies and tibial nerve palsies, presenting clinically as a foot drop. In two of our cases, the symptoms of foot drop occurred shortly after starting treatment for severe diabetes ketoacidosis. In the third patient, food drop was a reason for the initial medical consultation, but eventually, TID was diagnosed. The presented cases highlight that neuropathy can be observed not only as a chronic complication of T1D, but it can also appear at the time of disease manifestation. The incorrect position of the lower limb during a keto coma may contribute to the development of neuropathy.<\/jats:p>\n <\/jats:sec>\n \n Learning points<\/jats:title>\n \n \n Neuropathy can be observed not only as a chronic complication of type 1 diabetes (T1D), but it can also appear at the time of disease manifestation.<\/jats:p>\n <\/jats:list-item>\n \n The incorrect position of the lower limb causing external pressure during a keto coma may contribute to the development of neuropathy.<\/jats:p>\n <\/jats:list-item>\n \n It is important to examine the glycemia in patients with acute peroneal neuropathy, as this kind of peripheral neuropathy can be associated with newly diagnosed T1D. Normalization of glycemia might lead to rapid neuronal recovery.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:sec>","DOI":"10.1530\/edm-22-0417","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T05:16:53Z","timestamp":1693459013000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":2,"title":["Foot drop in children with newly diagnosed type 1 diabetes: three case reports"],"prefix":"10.1530","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3210-6681","authenticated-orcid":true,"given":"Joanna","family":"Chrzanowska","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Endocrinology, Diabetology and Metabolic Diseases for Children and Adolescents, Wroc\u0142aw Medical University, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Seifert","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Endocrinology, Diabetology and Metabolic Diseases for Children and Adolescents, Wroc\u0142aw Medical University, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Salmonowicz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Endocrinology, Diabetology and Metabolic Diseases for Children and Adolescents, Wroc\u0142aw Medical University, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Zubkiewicz-Kucharska","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Endocrinology, Diabetology and Metabolic Diseases for Children and Adolescents, Wroc\u0142aw Medical University, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Practical Neurology","first-page":"158","article-title":"Foot drop: where, why, and what to do?","volume":"8","author":"Stewart","year":"2008","unstructured":"Stewart JD. Foot drop: where, why, and what to do?Practical Neurology20088158\u2013169. (https:\/\/doi.org\/10.1136\/jnnp.2008.149393)"},{"key":"bib2","series-title":"Paediatrics and International Child Health","first-page":"69","article-title":"Permanent damage of the sciatic nerve in an 8-year-old girl with newly diagnosed type 1 diabetes","volume":"40","author":"Giza","year":"2020","unstructured":"Giza SLitou EKotanidou EPKleisarchaki ANKoliatos PTzirtzipis TTsinopoulou VRTychalas AEvangeliou A & Galli-Tsinopoulou A. Permanent damage of the sciatic nerve in an 8-year-old girl with newly diagnosed type 1 diabetes. Paediatrics and International Child Health20204069\u201371. (https:\/\/doi.org\/10.1080\/20469047.2019.1575536)"},{"key":"bib3","series-title":"Journal of Clinical Research in Pediatric Endocrinology","first-page":"289","article-title":"Peripheral neuropathy as a complication of diabetic ketoacidosis in a child with newly diagnosed diabetes type 1: a case report","volume":"10","author":"Baszy\u0144ska-Wilk","year":"2018","unstructured":"Baszy\u0144ska-Wilk MWysocka-Mincewicz M\u015awiercz A\u015awiderska JMarsza\u0142 M & Szalecki M. Peripheral neuropathy as a complication of diabetic ketoacidosis in a child with newly diagnosed diabetes type 1: a case report. Journal of Clinical Research in Pediatric Endocrinology201810289\u2013293. 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(https:\/\/doi.org\/10.4239\/wjd.v7.i17.342)"},{"key":"bib7","series-title":"Paediatrics and International Child Health","first-page":"105","article-title":"A 17-year-old boy who presented with acute mononeuropathy was found to have Type 1 diabetes","volume":"42","author":"\u00d6zg\u00fc\u00e7 \u00c7\u00f6mlek","year":"2022","unstructured":"\u00d6zg\u00fc\u00e7 \u00c7\u00f6mlek FKaral Y & T\u00fct\u00fcnc\u00fcler F. A 17-year-old boy who presented with acute mononeuropathy was found to have Type 1 diabetes. Paediatrics and International Child Health202242105\u2013107. (https:\/\/doi.org\/10.1080\/20469047.2022.2059879)"},{"key":"bib8","series-title":"Journal of Pediatric Endocrinology and Metabolism","first-page":"341","article-title":"Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus","volume":"28","author":"Rangel","year":"2015","unstructured":"Rangel MABaptista CSantos FReal MVCampos RA & Leite AL. Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus. Journal of Pediatric Endocrinology and Metabolism201528341\u2013344. (https:\/\/doi.org\/10.1515\/jpem-2014-0049)"},{"key":"bib9","series-title":"European Journal of Medical Case Reports","first-page":"44","article-title":"Acute mononeuropathy as the first presentation of pediatric type 1 diabetes mellitus: a case report","volume":"1","author":"Kapoor","year":"2017","unstructured":"Kapoor SSundaram PTziaferi V & Prasad M. Acute mononeuropathy as the first presentation of pediatric type 1 diabetes mellitus: a case report. European Journal of Medical Case Reports2017144\u201346. (https:\/\/doi.org\/10.24911\/ejmcr\/1\/11)"},{"key":"bib10","series-title":"Endocrinology, Diabetes and Metabolism Case Reports","first-page":"21","article-title":"Painless foot drop: an unusual acute presentation of new onset type 1 diabetes mellitus","volume":"2021","author":"Corcillo","year":"2021","unstructured":"Corcillo AKleinaki ZKapnisi SFountoulakis NMaltese GThomas SM & Karalliedde J. Painless foot drop: an unusual acute presentation of new onset type 1 diabetes mellitus. Endocrinology, Diabetes and Metabolism Case Reports2021202121\u20130012. 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