{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:12Z","timestamp":1784557032337,"version":"3.55.0"},"reference-count":10,"publisher":"Bioscientifica","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["edm.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Solid pseudopapillary neoplasm (SPN) is classified as an epithelial tumor identified from benign to low-grade malignant tumor. It is a relatively rare tumor among various pancreatic tumors and is generally observed in young women. Therefore, the identification of an SPN should be considered in cases where a solid\/cystic mass is detected in the pancreas of a young woman. Distal pancreatectomy is performed for a large size of SPN located in the tail of the pancreas. Here, we report a 15-year-old Japanese female who brought about Type 3C diabetes mellitus (T3C-DM) after a distal pancreatectomy due to SPN. This case highlights the importance of management after pancreatectomy to detect early T3C-DM and prevent its development even in young patients. Although it is not surprising that a massive pancreatic tumor or pancreatectomy can lead to pancreatic diabetes at any age, we believe that it is important for clinicians to know this subject for educational purposes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Learning points<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>SPN is a relatively rare tumor that accounts for 1\u20133% of all pancreatic tumors and is predominantly located in the tail of the pancreas.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Since SPN is generally observed in young women, the presence of an SPN should be considered in cases where a solid\/cystic mass is detected in the pancreas of a young woman.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Pancreatic DM after pancreatectomy is classified as T3C-DM in the American Diabetes Association (ADA) classification.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>This case indicates that even in young individuals, it is important to consider the possibility of impaired glucose tolerance after distal pancreatectomy.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>","DOI":"10.1530\/edm-24-0035","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T12:11:37Z","timestamp":1738671097000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":0,"title":["The onset of Type 3C diabetes mellitus in a young female due to distal pancreatectomy for solid pseudopapillary neoplasm"],"prefix":"10.1530","volume":"2025","author":[{"given":"Ayaka","family":"Harada","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7862-3385","authenticated-orcid":true,"given":"Takatoshi","family":"Anno","sequence":"additional","affiliation":[{"name":"Department of Diabetic Medicine, Kurashiki Central Hospital, Kurashiki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Kaku","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Kaneto","sequence":"additional","affiliation":[{"name":"Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Atlas of Tumor Pathology: Fascicles 22 and 28, Section 7","first-page":"32","article-title":"Tumors of the pancreas","author":"Frantz VK","year":"1959","unstructured":"Frantz VK. Tumors of the pancreas. In Atlas of Tumor Pathology: Fascicles 22 and 28, Section 7, pp. 32\u201333. Washington DC: US, Armed Forces Institute of Pathology, 1959."},{"key":"bib2","series-title":"In Vivo","first-page":"501","article-title":"Solid pseudopapillary tumor of the pancreas: a single-center experience and review of the literature","volume":"31","author":"Antoniou EA","year":"2017","unstructured":"Antoniou EA, Damaskos C, Garmpis N, et al. Solid pseudopapillary tumor of the pancreas: a single-center experience and review of the literature. In Vivo 2017 31 501\u2013510. (https:\/\/doi.org\/10.21873\/invivo.11089)"},{"key":"bib3","series-title":"World J Gastrointest Endosc","first-page":"145","article-title":"Clinical update on the management of pseudopapillary tumor of pancreas","volume":"10","author":"Lanke G","year":"2018","unstructured":"Lanke G, Ali FS & Lee JH. Clinical update on the management of pseudopapillary tumor of pancreas. 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