{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:19:09Z","timestamp":1783448349999,"version":"3.55.0"},"reference-count":20,"publisher":"Bioscientifica","issue":"1","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":165,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Non-ketotic hyperglycaemic hemichorea, also known as diabetic striatopathy (DS), is a rare but reversible hyperglycaemia-related movement disorder. It typically affects elderly patients and may occasionally represent the first manifestation of diabetes mellitus. The hallmark features include involuntary, unilateral choreiform or ballistic movements, with characteristic striatal neuroimaging changes. Early recognition is critical to avoid misdiagnosis and ensure timely intervention. We report a 78-year-old woman with a one-month history of progressive, involuntary right-sided limb movements, which subsided during sleep and severely impaired daily function. She had no prior diagnosis of diabetes but presented with osmotic symptoms for one year. Laboratory tests revealed hyperglycaemia (random blood glucose: 22 mmol\/L; HbA1c: 15.9%) without ketosis. Neuroimaging demonstrated hyperdensity in the left caudate and lentiform nucleus on CT and corresponding T1-weighted hyperintensity with asymmetrical striatal atrophy on MRI, consistent with DS. Treatment with insulin, haloperidol, and tetrabenazine achieved a gradual symptomatic improvement, with a marked reduction in involuntary movements at three months, although resolution was protracted compared to the typical cases. This case underscores the importance of considering DS in elderly patients presenting with acute choreiform movements, even in the absence of known diabetes. Awareness of its clinical and radiological features is crucial to prevent misdiagnosis as cerebrovascular disease. While optimal glycaemic control remains the cornerstone of management, persistent or severe cases may require prolonged anti-chorea therapy, reflecting potential irreversible striatal injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Learning points<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1530\/edm-25-0118","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T18:21:54Z","timestamp":1773426114000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-2","source":"Crossref","is-referenced-by-count":0,"title":["Non-ketotic hyperglycaemic hemichorea as the first manifestation of undiagnosed diabetes mellitus in an elderly patient"],"prefix":"10.1530","volume":"2026","author":[{"given":"Mohd Shazwan","family":"Sharudin","sequence":"first","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8204-102X","authenticated-orcid":true,"given":"Nur \u2018Aini","family":"Eddy Warman","sequence":"additional","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Katiman","sequence":"additional","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roqiah Fatmawati","family":"Abdul Kadir","sequence":"additional","affiliation":[{"name":"2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur Aisyah","family":"Zainordin","sequence":"additional","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mimi Nashra","family":"Mohd Noh","sequence":"additional","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Amelia","family":"Mohd 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