{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:58:31Z","timestamp":1787237911679,"version":"build-2736575974"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Radioiodine (RI) is an important therapeutic option in young patients with thyrotoxicosis. We wanted to determine whether RI is being used more frequently in this age group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>National survey of Great Britain (England, Wales and Scotland).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty-one medical physics departments were asked to provide the age and number of patients with thyrotoxicosis &lt;21 years treated with RI (1990\u20132008). Information on the total number of RI treatments for thyrotoxicosis was also collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty-three departments (70%), with representation from 21 of the 25 most populous areas of Great Britain, provided data on 69\u200a258 treatments. The number of treatments recorded on patients &lt;21 years during this period was 560 (0.9%). The frequency of treatments in young people as a percentage of the total increased from 0.2% in 1990 to 1.5% in 2008 (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001). When the 18 centres submitting at least 17 years of data were analysed, a similar pattern was observed. The maximum number of young people treated was greatest in 2008 (62) with a fall in the youngest age at which RI was administered from 18 years (1990) to 11 years (2008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A rising proportion of patients with thyrotoxicosis receiving RI are in those &lt;21 years. This is largely due to an increase in the number of young people treated with a reduction in the minimum age at RI administration. We suspect that European clinicians are becoming more comfortable with RI treatment in young people with thyrotoxicosis, although a changing incidence is a potential contributing factor.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/eje-12-0542","type":"journal-article","created":{"date-parts":[[2012,9,6]],"date-time":"2012-09-06T21:53:04Z","timestamp":1346968384000},"page":"715-718","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":8,"title":["Increasing use of radioiodine in young people with thyrotoxicosis in Great Britain"],"prefix":"10.1093","volume":"167","author":[{"given":"Neil","family":"Turner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Driver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane A","family":"Salotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Cheetham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"9","key":"1_18311333","doi-asserted-by":"publisher","first-page":"4229","DOI":"10.1210\/jc.2003-031223","volume":"89","author":"Read","year":"2004","journal-title":"Journal of Clinical Endocrinology &amp; 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