{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:20:06Z","timestamp":1782516006193,"version":"3.54.5"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec><jats:title>Context<\/jats:title><jats:p>Prevalence of Cushing's syndrome (CS) in patients presenting with hirsutism is not well known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Screening of CS in patients with hirsutism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Referral hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and other participants<\/jats:title><jats:p>This study was carried out on 105 patients who were admitted to the Endocrinology Department with the complaint of hirsutism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>All the patients were evaluated with low-dose dexamethasone suppression test (LDDST) for CS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>Response to LDDST in patients presenting with hirsutism.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All the patients had suppressed cortisol levels following low-dose dexamethasone administration excluding CS. The etiology of hirsutism was polycystic ovary syndrome in 79%, idiopathic hirsutism in 13%, idiopathic hyperandrogenemia in 6%, and nonclassical congenital hyperplasia in 2% of the patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Routine screening for CS in patients with a referral diagnosis of hirsutism is not required. For the time being, diagnostic tests for CS in hirsute patients should be limited to patients who have accompanying clinical stigmata of hypercortisolism.<\/jats:p><\/jats:sec>","DOI":"10.1530\/eje-12-0938","type":"journal-article","created":{"date-parts":[[2012,12,8]],"date-time":"2012-12-08T08:14:52Z","timestamp":1354954492000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":13,"title":["Routine screening for Cushing's syndrome is not required in patients presenting with hirsutism"],"prefix":"10.1093","volume":"168","author":[{"given":"Z","family":"Karaca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Acmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Acmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Tanriverdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Unluhizarci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Aribas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Kelestimur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"2","key":"1_41163545","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1093\/humupd\/dmr042","volume":"18","year":"2012","journal-title":"Human Reproduction Update","ISSN":"https:\/\/id.crossref.org\/issn\/1355-4786","issn-type":"print"},{"key":"2_26866871","doi-asserted-by":"crossref","first-page":"429","DOI":"10.2217\/17455057.1.3.429","volume":"1","year":"2005","journal-title":"Women's health (Hillsdale, N.J.)","ISSN":"https:\/\/id.crossref.org\/issn\/1077-2928","issn-type":"print"},{"issue":"8","key":"3_10921704","doi-asserted-by":"publisher","first-page":"2664","DOI":"10.1210\/jc.84.8.2664","volume":"84","author":"Colao","year":"1999","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"4_17660021","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.1210\/jc.2002-021558","volume":"88","author":"Faggiano","year":"2003","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"3","key":"5_42896538","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1530\/EJE-11-1095","volume":"167","year":"2012","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"10","key":"6_35272659","doi-asserted-by":"publisher","first-page":"3857","DOI":"10.1210\/jc.2008-2766","volume":"94","year":"2009","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"12","key":"7_17952018","doi-asserted-by":"publisher","first-page":"5808","DOI":"10.1210\/jc.2003-030254","volume":"88","author":"Catargi","year":"2003","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"8_36829254","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1210\/jc.2009-2453","volume":"95","year":"2010","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"3","key":"9_30509628","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1111\/j.1445-5994.2007.01434.x","volume":"38","author":"Newsome","year":"2008","journal-title":"Internal medicine journal","ISSN":"https:\/\/id.crossref.org\/issn\/1444-0903","issn-type":"print"},{"issue":"2","key":"10_29163396","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/j.1365-2265.2007.02865.x","volume":"67","author":"Reimondo","year":"2007","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"1","key":"11_40038773","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/j.1365-2362.2011.02550.x","volume":"42","author":"Unluhizarci","year":"2012","journal-title":"European journal of clinical investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0014-2972","issn-type":"print"},{"issue":"4","key":"12_30380942","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1210\/jc.2007-2437","volume":"93","year":"2008","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"7","key":"13_8433995","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0002-9378(81)90746-8","volume":"140","author":"Hatch","year":"1981","journal-title":"American journal of obstetrics and gynecology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9378","issn-type":"print"},{"issue":"1","key":"14_17987236","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.fertnstert.2003.10.004","volume":"81","year":"2004","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"8469-70","key":"15_13701203","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0140-6736(85)92552-8","volume":"2","author":"Adams","year":"1985","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"4","key":"16_15465102","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1210\/jc.78.4.810","volume":"78","author":"Azziz","year":"1994","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"2","key":"17_8990089","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1210\/jcem-57-2-320","volume":"57","author":"NEW","year":"1983","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"1","key":"18_36508095","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.ando.2009.12.009","volume":"71","author":"Young","year":"2010","journal-title":"Annales d'endocrinologie","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4266","issn-type":"print"},{"issue":"4","key":"19_16555004","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1046\/j.1365-2265.1996.8150825.x","volume":"45","author":"Kele\u00a0\u00a0timur","year":"1996","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"4","key":"20_10494645","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1046\/j.1365-2265.2000.01117.x","volume":"53","author":"Kaltsas","year":"2000","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"2","key":"21_18824692","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.ecl.2005.01.010","volume":"34","author":"Pivonello","year":"2005","journal-title":"Endocrinology and metabolism clinics of North America","ISSN":"https:\/\/id.crossref.org\/issn\/0889-8529","issn-type":"print"},{"key":"22_43500103","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ejim.2011.10.013","volume":"23","year":"2012","journal-title":"EUROPEAN JOURNAL OF INTERNAL MEDICINE"},{"issue":"4","key":"23_40011614","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1111\/j.1365-2265.2011.04124.x","volume":"75","author":"Bolland","year":"2011","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"4","key":"24_41570752","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1210\/jc.2011-2957","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"25_42079768","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1210\/jc.2011-3123","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"26_18562099","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1016\/j.fertnstert.2004.06.040","volume":"82","author":"Glintborg","year":"2004","journal-title":"Fertility and sterility","ISSN":"https:\/\/id.crossref.org\/issn\/0015-0282","issn-type":"print"},{"issue":"8","key":"27_30322300","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1590\/S0004-27302007000800003","volume":"51","author":"Caetano","year":"2007","journal-title":"Arquivos brasileiros de endocrinologia e metabologia","ISSN":"https:\/\/id.crossref.org\/issn\/0004-2730","issn-type":"print"},{"issue":"6","key":"28_19729104","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1530\/eje.1.02045","volume":"153","author":"Chiodini","year":"2005","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"1279","key":"29_31301151","first-page":"100","volume":"121","author":"Browne","year":"2008","journal-title":"The New Zealand medical journal","ISSN":"https:\/\/id.crossref.org\/issn\/0028-8446","issn-type":"print"},{"issue":"3","key":"30_41805716","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/dmrr.2262","volume":"28","author":"Therese","year":"2012","journal-title":"Diabetes\/metabolism research and reviews","ISSN":"https:\/\/id.crossref.org\/issn\/1520-7552","issn-type":"print"},{"issue":"1","key":"31_38342426","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11695-010-0297-6","volume":"21","author":"Fierabracci","year":"2011","journal-title":"Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand","ISSN":"https:\/\/id.crossref.org\/issn\/0960-8923","issn-type":"print"},{"issue":"1","key":"32_41162515","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s11695-011-0545-4","volume":"22","author":"Jankovic","year":"2012","journal-title":"Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand","ISSN":"https:\/\/id.crossref.org\/issn\/0960-8923","issn-type":"print"},{"key":"33_45189689","first-page":"9","volume":"65","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/0097-3521","issn-type":"print"},{"issue":"8","key":"34_29562562","doi-asserted-by":"crossref","first-page":"541","DOI":"10.7326\/0003-4819-147-8-200710160-00006","volume":"147","author":"Chiodini","year":"2007","journal-title":"Annals of Internal Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"35_45189665","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrendo.2011.51","volume":"7","year":"2011","journal-title":"NATURE REVIEWS ENDOCRINOLOGY"},{"issue":"3","key":"36_15711586","first-page":"311","volume":"25","author":"Mor\u00a0\u00a0n","year":"1994","journal-title":"Archives of medical research","ISSN":"https:\/\/id.crossref.org\/issn\/0188-0128","issn-type":"print"},{"issue":"2","key":"37_15621359","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1365-2265.1994.tb02535.x","volume":"41","author":"O'Driscoll","year":"1994","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"key":"38_36402860","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1055\/s-2004-821307","volume":"112","year":"2004","journal-title":"EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY DIABETES"}],"container-title":["European Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/168\/3\/379.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/168\/3\/379.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:28:55Z","timestamp":1676392135000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/168\/3\/379\/6659710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":38,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/eje-12-0938","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}