{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:23:50Z","timestamp":1792167830171,"version":"4.4.0"},"reference-count":183,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>Obesity and thyroid diseases are common disorders in the general population and they frequently occur in single individuals. Alongside a chance association, a direct relationship between \u2018thyroid and obesity\u2019 has been hypothesized. Thyroid hormone is an important determinant of energy expenditure and contributes to appetite regulation, while hormones and cytokines from the adipose tissue act on the CNS to inform on the quantity of energy stores. A continuous interaction between the thyroid hormone and regulatory mechanisms localized in adipose tissue and brain is important for human body weight control and maintenance of optimal energy balance. Whether obesity has a pathogenic role in thyroid disease remains largely a matter of investigation. This review highlights the complexity in the identification of thyroid hormone deficiency in obese patients. Regardless of the importance of treating subclinical and overt hypothyroidism, at present there is no evidence to recommend pharmacological correction of the isolated hyperthyrotropinemia often encountered in obese patients. While thyroid hormones are not indicated as anti-obesity drugs, preclinical studies suggest that thyromimetic drugs, by targeting selected receptors, might be useful in the treatment of obesity and dyslipidemia.<\/jats:p>","DOI":"10.1530\/eje-14-0067","type":"journal-article","created":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T04:54:38Z","timestamp":1410497678000},"page":"R137-R152","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":205,"title":["MECHANISMS IN ENDOCRINOLOGY: The crosstalk between thyroid gland and adipose tissue: signal integration in health and disease"],"prefix":"10.1093","volume":"171","author":[{"given":"Ferruccio","family":"Santini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Marzullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Rotondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Ceccarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Pagano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Ippolito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Chiovato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Biondi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"8","key":"1_37738568","doi-asserted-by":"publisher","first-page":"3614","DOI":"10.1210\/jc.2010-1245","volume":"95","author":"Biondi","year":"2010","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"2","key":"2_39128357","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1210\/jc.2010-2515","volume":"96","author":"Rotondi","year":"2011","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"key":"3_48560122","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000342994","volume":"1","year":"2012","journal-title":"EUROPEAN THYROID JOURNAL"},{"key":"4_48560123","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/MED.0b013e328355cd6c","volume":"19","year":"2012","journal-title":"CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY"},{"key":"5_47543515","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1089\/thy.2011.0499","volume":"23","year":"2013","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"6937","key":"6_3293655","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0140-6736(56)92080-3","volume":"271","author":"Baron","year":"1956","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"1","key":"7_7145936","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1056\/NEJM196607072750103","volume":"275","author":"Kyle","year":"1966","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"3038","key":"8_33359205","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1136\/bmj.1.3038.335","volume":"1","author":"Johnson","year":"1919","journal-title":"BMJ","ISSN":"https:\/\/id.crossref.org\/issn\/0959-8138","issn-type":"print"},{"issue":"5","key":"9_39542005","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/BF03347465","volume":"34","author":"Marsili","year":"2011","journal-title":"Journal of endocrinological investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"9","key":"10_42971696","doi-asserted-by":"publisher","first-page":"4128","DOI":"10.1210\/en.2012-1467","volume":"153","year":"2012","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"2","key":"11_21863221","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1152\/physrev.00009.2005","volume":"86","author":"Silva","year":"2006","journal-title":"Physiological Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0031-9333","issn-type":"print"},{"issue":"2","key":"12_23295048","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1093\/emboj\/17.2.455","volume":"17","author":"Wikstrom","year":"1998","journal-title":"The EMBO Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0261-4189","issn-type":"print"},{"issue":"7","key":"13_18913091","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.1210\/en.2004-1544","volume":"146","year":"2005","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"8","key":"14_17169549","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1210\/me.2002-0009","volume":"16","year":"2002","journal-title":"Molecular Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0888-8809","issn-type":"print"},{"issue":"2","key":"15_18347239","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1210\/me.2003-0267","volume":"18","year":"2004","journal-title":"Molecular Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0888-8809","issn-type":"print"},{"key":"16_48560125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.brainres.2013.04.017","volume":"1516","year":"2013","journal-title":"Brain research","ISSN":"https:\/\/id.crossref.org\/issn\/0006-8993","issn-type":"print"},{"issue":"2","key":"17_30489035","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1089\/thy.2007.0254","volume":"18","author":"Obregon","year":"2008","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"12","key":"18_17951985","doi-asserted-by":"publisher","first-page":"5605","DOI":"10.1210\/jc.2003-030576","volume":"88","author":"Haluzik","year":"2003","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"9","key":"19_38028787","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1038\/nm.2207","volume":"16","author":"Lopez","year":"2010","journal-title":"Nature medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"key":"20_48011599","first-page":"3956","volume":"1830","year":"2013","journal-title":"Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology","ISSN":"https:\/\/id.crossref.org\/issn\/0006-3002","issn-type":"print"},{"issue":"12","key":"21_46591572","doi-asserted-by":"publisher","first-page":"E1956","DOI":"10.1210\/jc.2013-2387","volume":"98","year":"2013","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"15","key":"22_34502172","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1056\/NEJMoa0810780","volume":"360","author":"Cypess","year":"2009","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"key":"23_47718907","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1172\/JCI68993","volume":"123","year":"2013","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"key":"24_47718909","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1172\/JCI67803","volume":"123","year":"2013","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"2","key":"25_43218332","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.cell.2012.05.016","volume":"150","author":"Wu","year":"2012","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"11","key":"26_44266534","doi-asserted-by":"publisher","first-page":"e49452","DOI":"10.1371\/journal.pone.0049452","volume":"7","author":"Sharp","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"7971","key":"27_4005470","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/S0140-6736(76)92158-9","volume":"1","author":"Bray","year":"1976","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"1","key":"28_3936434","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1210\/jcem-42-1-197","volume":"42","author":"Spaulding","year":"1976","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"29_4408925","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1210\/jcem-45-6-1305","volume":"45","author":"VAGENAKIS","year":"1977","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"30_4529252","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/0026-0495(78)90096-3","volume":"27","author":"Visser","year":"1978","journal-title":"Metabolism: clinical and experimental","ISSN":"https:\/\/id.crossref.org\/issn\/0026-0495","issn-type":"print"},{"issue":"5","key":"31_7972377","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1172\/JCI109590","volume":"64","author":"Danforth","year":"1979","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"1","key":"32_12854321","first-page":"44","volume":"90","author":"Rimm","year":"1975","journal-title":"Public health reports","ISSN":"https:\/\/id.crossref.org\/issn\/0033-3549","issn-type":"print"},{"key":"33_36794236","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.cmet.2006.12.002","volume":"5","year":"2007","journal-title":"CELL METABOLISM"},{"issue":"9","key":"34_36609492","doi-asserted-by":"publisher","first-page":"4471","DOI":"10.1073\/pnas.0905190107","volume":"107","year":"2010","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"35_35714588","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0065-2423(09)48004-1","volume":"48","author":"Santini","year":"2009","journal-title":"Advances in clinical chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0065-2423","issn-type":"print"},{"key":"36_48560126","first-page":"387562","volume":"2011","year":"2011","journal-title":"JOURNAL OF THYROID RESEARCH"},{"issue":"6704","key":"37_6208041","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1038\/27376","volume":"395","author":"Friedman","year":"1998","journal-title":"Nature","ISSN":"https:\/\/id.crossref.org\/issn\/0028-0836","issn-type":"print"},{"issue":"8","key":"38_40601358","doi-asserted-by":"crossref","first-page":"e23364","DOI":"10.1371\/journal.pone.0023364","volume":"6","author":"Ribeiro","year":"2011","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"39_47632739","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.molmed.2013.04.004","volume":"19","year":"2013","journal-title":"Trends in molecular medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1471-4914","issn-type":"print"},{"key":"40_37492474","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.cmet.2009.07.001","volume":"10","year":"2009","journal-title":"CELL METABOLISM"},{"issue":"2","key":"41_36509179","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.yfrne.2010.01.001","volume":"31","author":"Nillni","year":"2010","journal-title":"Frontiers in neuroendocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0091-3022","issn-type":"print"},{"issue":"6","key":"42_16792058","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1210\/en.138.6.2569","volume":"138","author":"Legradi","year":"1997","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"6","key":"43_18862727","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1210\/en.2004-1361","volume":"146","year":"2005","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"7","key":"44_6539192","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1172\/JCI8857","volume":"105","author":"Kim","year":"2000","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"7","key":"45_11226624","doi-asserted-by":"publisher","first-page":"3284","DOI":"10.1210\/jc.86.7.3284","volume":"86","author":"Mantzoros","year":"2001","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"9","key":"46_17611107","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1172\/JCI200317490","volume":"111","author":"Chan","year":"2003","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"12","key":"47_19731215","doi-asserted-by":"publisher","first-page":"3579","DOI":"10.1172\/JCI25977","volume":"115","author":"Rosenbaum","year":"2005","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"8","key":"48_17295556","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1172\/JCI200215693","volume":"110","year":"2002","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"key":"49_48560127","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1756-6614-2-11","volume":"2","year":"2009","journal-title":"THYROID RESEARCH"},{"issue":"2","key":"50_18171435","doi-asserted-by":"crossref","first-page":"RC5","DOI":"10.1007\/BF03346252","volume":"27","author":"Santini","year":"2004","journal-title":"Journal of endocrinological investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"5","key":"51_28819145","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1089\/thy.2007.0032","volume":"17","author":"Feldt-Rasmussen","year":"2007","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"11-12","key":"52_10646274","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1055\/s-2007-978672","volume":"32","author":"Sorisky","year":"2000","journal-title":"Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et m&#x00A0;&#x00A0;tabolisme","ISSN":"https:\/\/id.crossref.org\/issn\/0018-5043","issn-type":"print"},{"issue":"1","key":"53_37098672","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1530\/EJE-10-0138","volume":"163","year":"2010","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"7926","key":"54_12944253","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0140-6736(75)90061-6","volume":"2","author":"Doniach","year":"1975","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"4","key":"55_9764384","doi-asserted-by":"publisher","first-page":"1857","DOI":"10.1210\/en.130.4.1857","volume":"130","author":"Roselli-Rehfuss","year":"1992","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"3","key":"56_11036840","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1210\/en.142.3.1195","volume":"142","author":"Murakami","year":"2001","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"2","key":"57_31307385","doi-asserted-by":"publisher","first-page":"E514","DOI":"10.1152\/ajpendo.90433.2008","volume":"295","year":"2008","journal-title":"American Journal of Physiology - Endocrinology And Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0193-1849","issn-type":"print"},{"issue":"1","key":"58_39806885","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1530\/EJE-11-0261","volume":"165","year":"2011","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"6","key":"59_6126395","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1046\/j.1365-2265.1998.00400.x","volume":"48","author":"Wesche","year":"1998","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"2","key":"60_17722934","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1046\/j.1365-2265.2003.01836.x","volume":"59","author":"Sari","year":"2003","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"7","key":"61_19251285","doi-asserted-by":"publisher","first-page":"4019","DOI":"10.1210\/jc.2004-2225","volume":"90","year":"2005","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"62_32056036","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1111\/j.1365-2265.2008.03239.x","volume":"69","author":"Makepeace","year":"2008","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"key":"63_40151067","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3904\/kjim.2008.23.2.53","volume":"23","year":"2008","journal-title":"KOREAN JOURNAL OF INTERNAL MEDICINE"},{"issue":"3","key":"64_32849351","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1530\/EJE-08-0734","volume":"160","year":"2009","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"3","key":"65_35406735","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1530\/EJE-09-0441","volume":"161","author":"Alevizaki","year":"2009","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"8","key":"66_37420050","doi-asserted-by":"publisher","first-page":"3965","DOI":"10.1210\/jc.2009-2798","volume":"95","year":"2010","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"67_42404727","doi-asserted-by":"crossref","first-page":"e34979","DOI":"10.1371\/journal.pone.0034979","volume":"7","author":"Kitahara","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"9","key":"68_46092365","doi-asserted-by":"publisher","first-page":"3562","DOI":"10.1210\/jc.2013-1315","volume":"98","year":"2013","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"9","key":"69_46442433","doi-asserted-by":"publisher","first-page":"3584","DOI":"10.1210\/jc.2013-2760","volume":"98","author":"Biondi","year":"2013","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"70_10339987","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1093\/ajcn\/71.6.1421","volume":"71","author":"Rosenbaum","year":"2000","journal-title":"The American Journal of Clinical Nutrition","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9165","issn-type":"print"},{"issue":"8","key":"71_19316663","doi-asserted-by":"publisher","first-page":"4659","DOI":"10.1210\/jc.2005-0920","volume":"90","year":"2005","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"9","key":"72_21484071","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1381\/096089205774512537","volume":"15","author":"Moulin de Moraes","year":"2005","journal-title":"Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand","ISSN":"https:\/\/id.crossref.org\/issn\/0960-8923","issn-type":"print"},{"issue":"4","key":"73_7123974","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1210\/jcem-26-4-425","volume":"26","author":"ODDIE","year":"1966","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"1","key":"74_18610146","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1210\/jc.2004-1306","volume":"90","year":"2005","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"key":"75_45420303","doi-asserted-by":"crossref","first-page":"988","DOI":"10.4158\/EP12280.GL","volume":"18","year":"2012","journal-title":"ENDOCRINE PRACTICE"},{"key":"76_48560129","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s12020-013-9928-8","volume":"45","year":"2014","journal-title":"Endocrine","ISSN":"https:\/\/id.crossref.org\/issn\/0969-711X","issn-type":"print"},{"issue":"12","key":"77_32095057","doi-asserted-by":"publisher","first-page":"4749","DOI":"10.1210\/jc.2008-0823","volume":"93","year":"2008","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"1","key":"78_37246564","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1530\/EJE-10-0288","volume":"163","year":"2010","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"10","key":"79_11439746","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1007\/BF03343925","volume":"24","author":"Rago","year":"2001","journal-title":"Journal of endocrinological investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"7470","key":"80_7194423","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0140-6736(66)90536-8","volume":"2","author":"Ramsay","year":"1966","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"6","key":"81_13238109","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/0002-9343(84)90842-8","volume":"76","author":"Hoogwerf","year":"1984","journal-title":"The American journal of medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9343","issn-type":"print"},{"issue":"3","key":"82_16713311","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1210\/jc.82.3.765","volume":"82","author":"Lovejoy","year":"1997","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"83_16812225","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1530\/eje.0.1360493","volume":"136","author":"Seppel","year":"1997","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"6","key":"84_19633966","doi-asserted-by":"publisher","first-page":"E1067","DOI":"10.1152\/ajpendo.00253.2004","volume":"288","year":"2005","journal-title":"American Journal of Physiology - Endocrinology And Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0193-1849","issn-type":"print"},{"issue":"3","key":"85_17752660","doi-asserted-by":"publisher","first-page":"205","DOI":"10.7326\/0003-4819-139-3-200308050-00018","volume":"139","author":"Silva","year":"2003","journal-title":"Annals of Internal Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"issue":"6","key":"86_9668365","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1172\/JCI115533","volume":"88","author":"Martin","year":"1991","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"4","key":"87_12409548","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1210\/jcem-36-4-742","volume":"36","author":"COHN","year":"1973","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"12","key":"88_6261223","doi-asserted-by":"publisher","first-page":"4269","DOI":"10.1210\/jc.83.12.4269","volume":"83","author":"Lonn","year":"1998","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"2","key":"89_10785316","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/07315724.1999.10718849","volume":"18","author":"Abid","year":"1999","journal-title":"Journal of the American College of Nutrition","ISSN":"https:\/\/id.crossref.org\/issn\/0731-5724","issn-type":"print"},{"issue":"2","key":"90_11303963","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1046\/j.1365-2265.2001.01329.x","volume":"55","author":"Dale","year":"2001","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"key":"91_48560130","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1463-1326.2005.00486.x","volume":"8","year":"2006","journal-title":"DIABETES OBESITY METABOLISM"},{"key":"92_41312077","doi-asserted-by":"crossref","first-page":"973","DOI":"10.4158\/EP.14.8.973","volume":"14","year":"2008","journal-title":"ENDOCRINE PRACTICE"},{"issue":"2","key":"93_43592310","first-page":"242","volume":"136","author":"Dutta","year":"2012","journal-title":"The Indian journal of medical research","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5916","issn-type":"print"},{"key":"94_48560131","first-page":"715370","volume":"2011","year":"2011","journal-title":"INTERNATIONAL JOURNAL OF ENDOCRINOLOGY"},{"issue":"6","key":"95_39786600","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1089\/thy.2010.0417","volume":"21","author":"Bahn Chair","year":"2011","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"5","key":"96_13080226","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/BF03347623","volume":"6","author":"Wenzel","year":"1983","journal-title":"Journal of endocrinological investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"3","key":"97_13160047","doi-asserted-by":"crossref","first-page":"372","DOI":"10.7326\/0003-4819-100-3-372","volume":"100","author":"TAKAMATSU","year":"1984","journal-title":"Annals of Internal Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"issue":"3","key":"98_16713312","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1210\/jc.82.3.771","volume":"82","author":"Zulewski","year":"1997","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"99_42767631","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1111\/j.1365-2265.2012.04455.x","volume":"77","author":"Carle","year":"2012","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"4","key":"100_6464270","first-page":"270","volume":"132","year":"2000","journal-title":"Annals of Internal Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"issue":"2","key":"101_16215213","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1530\/eje.0.1340168","volume":"134","author":"Wolf","year":"1996","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"3","key":"102_5379261","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1210\/edrv-10-3-366","volume":"10","author":"SMITH","year":"1989","journal-title":"Endocrine Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0163-769X","issn-type":"print"},{"issue":"4","key":"103_4550008","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/0002-9343(78)90581-8","volume":"64","author":"Skowsky","year":"1978","journal-title":"The American journal of medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9343","issn-type":"print"},{"issue":"4","key":"104_16745707","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1210\/jc.82.4.1118","volume":"82","author":"Al-Adsani","year":"1997","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"105_39255783","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1089\/thy.2010.0315","volume":"21","author":"Boeving","year":"2011","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"106_38238378","doi-asserted-by":"publisher","first-page":"E99","DOI":"10.1210\/jc.2010-1521","volume":"96","year":"2011","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"107_17660067","doi-asserted-by":"publisher","first-page":"2825","DOI":"10.1210\/jc.2002-021439","volume":"88","author":"Santini","year":"2003","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"8","key":"108_16293835","doi-asserted-by":"publisher","first-page":"3308","DOI":"10.1210\/en.137.8.3308","volume":"137","author":"Salvatore","year":"1996","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"1-2","key":"109_16296040","first-page":"10","volume":"23","author":"Visser","year":"1996","journal-title":"Acta medica Austriaca","ISSN":"https:\/\/id.crossref.org\/issn\/0303-8173","issn-type":"print"},{"issue":"5","key":"110_17867939","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1210\/er.2002-0030","volume":"24","author":"Tomer","year":"2003","journal-title":"Endocrine Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0163-769X","issn-type":"print"},{"issue":"10","key":"111_29410676","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1111\/j.1398-9995.2007.01506.x","volume":"62","author":"Hersoug","year":"2007","journal-title":"Allergy","ISSN":"https:\/\/id.crossref.org\/issn\/0105-4538","issn-type":"print"},{"key":"112_48560132","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1586\/eci.11.18","volume":"7","year":"2011","journal-title":"EXPERT REVIEW OF CLINICAL IMMUNOLOGY"},{"issue":"10","key":"113_22639964","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1038\/nri1937","volume":"6","author":"Tilg","year":"2006","journal-title":"Nature reviews. Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1733","issn-type":"print"},{"key":"114_48560133","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.celrep.2013.03.006","volume":"3","year":"2013","journal-title":"CELL REPORTS"},{"issue":"3","key":"115_37517297","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.4049\/jimmunol.1000021","volume":"185","year":"2010","journal-title":"The Journal of Immunology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1767","issn-type":"print"},{"key":"116_22494605","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.0105-2896.2006.00427.x","volume":"212","author":"Sakaguchi","year":"2006","journal-title":"Immunological reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0105-2896","issn-type":"print"},{"issue":"4","key":"117_32612654","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1210\/en.2008-1389","volume":"150","year":"2009","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"118_48560134","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1100\/2011\/290142","volume":"11","year":"2011","journal-title":"SCIENTIFIC WORLD JOURNAL"},{"issue":"4","key":"119_39553932","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1097\/MOP.0b013e328344c393","volume":"23","author":"Reinehr","year":"2011","journal-title":"Current opinion in pediatrics","ISSN":"https:\/\/id.crossref.org\/issn\/1040-8703","issn-type":"print"},{"issue":"3-4","key":"120_41358490","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.cca.2011.11.013","volume":"413","author":"Pacifico","year":"2012","journal-title":"Clinica Chimica Acta","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3492","issn-type":"print"},{"issue":"1","key":"121_10638490","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1159\/000063431","volume":"54","author":"Stichel","year":"2000","journal-title":"Hormone research","ISSN":"https:\/\/id.crossref.org\/issn\/0301-0163","issn-type":"print"},{"issue":"7","key":"122_29182427","first-page":"773","volume":"99","author":"Bhowmick","year":"2007","journal-title":"Journal of the National Medical Association","ISSN":"https:\/\/id.crossref.org\/issn\/0027-9684","issn-type":"print"},{"issue":"8","key":"123_17168929","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.2337\/diacare.25.8.1346","volume":"25","author":"Kordonouri","year":"2002","journal-title":"Diabetes Care","ISSN":"https:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"issue":"3","key":"124_17519945","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1530\/eje.0.1480301","volume":"148","author":"Kabelitz","year":"2003","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"7","key":"125_31554996","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1089\/thy.2007.0370","volume":"18","author":"Kaloumenou","year":"2008","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"126_38342426","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1007\/s11695-010-0297-6","volume":"21","author":"Fierabracci","year":"2011","journal-title":"Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand","ISSN":"https:\/\/id.crossref.org\/issn\/0960-8923","issn-type":"print"},{"issue":"2","key":"127_16908699","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1210\/jc.87.2.489","volume":"87","author":"Hollowell","year":"2002","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"1-2","key":"128_23135477","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.cca.2006.07.018","volume":"376","author":"La'ulu","year":"2007","journal-title":"Clinica Chimica Acta","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3492","issn-type":"print"},{"issue":"5","key":"129_9250076","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1530\/acta.0.1230493","volume":"123","author":"Prentice","year":"1990","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"3","key":"130_10182190","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1365-2265.1993.tb01006.x","volume":"38","author":"Konno","year":"1993","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"1","key":"131_15973357","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/j.1365-2265.1995.tb01894.x","volume":"43","author":"Vanderpump","year":"1995","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"5","key":"132_10551785","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1530\/eje.0.1430639","volume":"143","author":"Bjoro","year":"2000","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"11-12","key":"133_17927386","first-page":"591","volume":"49","author":"Z\u00a0\u00a0phel","year":"2003","journal-title":"Clinical laboratory","ISSN":"https:\/\/id.crossref.org\/issn\/1433-6510","issn-type":"print"},{"issue":"1","key":"134_21386391","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1111\/j.1365-2265.2005.02424.x","volume":"64","author":"O'leary","year":"2006","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"1","key":"135_21080399","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1373\/clinchem.2005.055194","volume":"52","year":"2006","journal-title":"Clinical Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9147","issn-type":"print"},{"issue":"1","key":"136_21645859","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1089\/thy.2006.16.73","volume":"16","author":"Michalaki","year":"2006","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"9","key":"137_35451491","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1089\/thy.2009.0205","volume":"19","author":"Kasagi","year":"2009","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"12","key":"138_43582714","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1089\/thy.2012.0205","volume":"22","author":"Garber","year":"2012","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"139_39931966","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1210\/er.2006-0043","volume":"29","year":"2008","journal-title":"Endocrine Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0163-769X","issn-type":"print"},{"issue":"9821","key":"140_41768415","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/S0140-6736(11)60276-6","volume":"379","author":"Cooper","year":"2012","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"1","key":"141_39098419","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1055\/s-0030-1270068","volume":"37","author":"Duntas","year":"2011","journal-title":"Seminars in thrombosis and hemostasis","ISSN":"https:\/\/id.crossref.org\/issn\/0094-6176","issn-type":"print"},{"issue":"38","key":"142_18297876","doi-asserted-by":"publisher","first-page":"6365","DOI":"10.1038\/sj.onc.1207751","volume":"23","author":"Calle","year":"2004","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"6","key":"144_28646839","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1053\/j.gastro.2007.03.052","volume":"132","author":"Ogden","year":"2007","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"issue":"3","key":"145_39027390","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1158\/1055-9965.EPI-10-1220","volume":"20","year":"2011","journal-title":"Cancer Epidemiology Biomarkers &amp; Prevention","ISSN":"https:\/\/id.crossref.org\/issn\/1055-9965","issn-type":"print"},{"issue":"6","key":"146_45482079","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1530\/EJE-13-0065","volume":"168","year":"2013","journal-title":"European Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0804-4643","issn-type":"print"},{"issue":"4","key":"147_35301270","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1677\/ERC-09-0150","volume":"16","year":"2009","journal-title":"Endocrine-Related Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1351-0088","issn-type":"print"},{"issue":"4","key":"148_35052846","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1677\/ERC-09-0036","volume":"16","year":"2009","journal-title":"Endocrine-Related Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1351-0088","issn-type":"print"},{"issue":"8","key":"149_42619263","doi-asserted-by":"publisher","first-page":"2682","DOI":"10.1210\/jc.2012-1083","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"5","key":"150_39420367","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1007\/s10552-011-9747-2","volume":"22","author":"Almquist","year":"2011","journal-title":"Cancer causes &amp; control : CCC","ISSN":"https:\/\/id.crossref.org\/issn\/0957-5243","issn-type":"print"},{"issue":"3","key":"151_38753893","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1210\/jc.2010-1255","volume":"96","year":"2011","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"key":"152_48560135","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1089\/thy.2013.0232","volume":"24","year":"2014","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"6","key":"153_29907012","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1111\/j.1365-2184.2007.00471.x","volume":"40","author":"Zeng","year":"2007","journal-title":"Cell proliferation","ISSN":"https:\/\/id.crossref.org\/issn\/0960-7722","issn-type":"print"},{"issue":"1-2","key":"154_32750116","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s11010-008-9969-0","volume":"323","author":"Karaoglu","year":"2009","journal-title":"Molecular and cellular biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0300-8177","issn-type":"print"},{"issue":"6","key":"155_43265316","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1210\/er.2011-1007","volume":"33","year":"2012","journal-title":"Endocrine Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0163-769X","issn-type":"print"},{"issue":"2","key":"156_17479611","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0002-9440(10)63858-8","volume":"162","author":"Volante","year":"2003","journal-title":"American Journal Of Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"issue":"6","key":"157_37200017","first-page":"1721","volume":"23","author":"Cheng","year":"2010","journal-title":"Oncology reports","ISSN":"https:\/\/id.crossref.org\/issn\/1021-335X","issn-type":"print"},{"issue":"1","key":"158_36168787","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1677\/ERC-09-0153","volume":"17","year":"2010","journal-title":"Endocrine-Related Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1351-0088","issn-type":"print"},{"issue":"8","key":"159_45970559","doi-asserted-by":"publisher","first-page":"2936","DOI":"10.1210\/en.2013-1128","volume":"154","year":"2013","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"key":"160_48560136","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s00428-013-1453-x","volume":"463","year":"2013","journal-title":"Virchows Archiv : an international journal of pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0945-6317","issn-type":"print"},{"key":"161_48560137","first-page":"1","volume":"387062","year":"2011","journal-title":"JOURNAL OF THYROID RESEARCH"},{"key":"162_48560138","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11695-013-1079-8","volume":"24","year":"2014","journal-title":"Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand","ISSN":"https:\/\/id.crossref.org\/issn\/0960-8923","issn-type":"print"},{"issue":"6","key":"163_8577879","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1111\/j.1365-2265.1981.tb00708.x","volume":"15","author":"Moreira-Andr\u00a0\u00a0s","year":"1981","journal-title":"Clinical endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"8162","key":"164_8039988","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S0140-6736(80)90715-1","volume":"1","author":"Moore","year":"1980","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"8","key":"165_7878721","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/0026-0495(79)90206-3","volume":"28","author":"Burman","year":"1979","journal-title":"Metabolism: clinical and experimental","ISSN":"https:\/\/id.crossref.org\/issn\/0026-0495","issn-type":"print"},{"issue":"6","key":"166_13776535","first-page":"459","volume":"9","author":"Wolman","year":"1985","journal-title":"International journal of obesity","ISSN":"https:\/\/id.crossref.org\/issn\/0307-0565","issn-type":"print"},{"issue":"4","key":"167_22061959","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1089\/thy.2006.16.375","volume":"16","author":"Brennan","year":"2006","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"10","key":"168_35555851","doi-asserted-by":"publisher","first-page":"3663","DOI":"10.1210\/jc.2009-0899","volume":"94","year":"2009","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"4","key":"169_13963673","first-page":"303","volume":"10","author":"Rozen","year":"1986","journal-title":"International journal of obesity","ISSN":"https:\/\/id.crossref.org\/issn\/0307-0565","issn-type":"print"},{"issue":"11","key":"170_13650654","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1016\/0026-0495(85)90081-2","volume":"34","author":"Koppeschaar","year":"1985","journal-title":"Metabolism: clinical and experimental","ISSN":"https:\/\/id.crossref.org\/issn\/0026-0495","issn-type":"print"},{"issue":"2","key":"171_8988456","first-page":"133","volume":"7","author":"Koppeschaar","year":"1983","journal-title":"International journal of obesity","ISSN":"https:\/\/id.crossref.org\/issn\/0307-0565","issn-type":"print"},{"issue":"4","key":"172_34505087","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1038\/nrd2830","volume":"8","author":"Baxter","year":"2009","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"key":"173_48560140","first-page":"39","volume":"311","year":"2010","journal-title":"Endocrine Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0163-769X","issn-type":"print"},{"issue":"1-5","key":"174_11175460","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S0960-0760(01)00052-8","volume":"76","author":"Baxter","year":"2001","journal-title":"The Journal of steroid biochemistry and molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0960-0760","issn-type":"print"},{"issue":"2","key":"175_30489040","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1089\/thy.2007.0248","volume":"18","author":"Moreno","year":"2008","journal-title":"Thyroid : official journal of the American Thyroid Association","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"key":"176_48560141","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1039\/c2mb25055a","volume":"8","year":"2012","journal-title":"MOLECULAR BIOSYSTEMS"},{"key":"177_40116674","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/MED.0b013e32833cf354","volume":"17","year":"2010","journal-title":"CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY"},{"issue":"7","key":"178_12267471","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1001\/jama.1972.03200070084015","volume":"220","author":"The Coronary Drug Project Research Group","year":"1972","journal-title":"JAMA","ISSN":"https:\/\/id.crossref.org\/issn\/0098-7484","issn-type":"print"},{"issue":"7","key":"179_16838403","doi-asserted-by":"publisher","first-page":"2153","DOI":"10.1210\/jc.82.7.2153","volume":"82","author":"Sherman","year":"1997","journal-title":"Journal of Clinical Endocrinology &amp; Metabolism","ISSN":"https:\/\/id.crossref.org\/issn\/0021-972X","issn-type":"print"},{"issue":"6","key":"180_6066660","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/S1074-5521(98)90168-5","volume":"5","author":"Chiellini","year":"1998","journal-title":"Chemistry &amp; biology","ISSN":"https:\/\/id.crossref.org\/issn\/1074-5521","issn-type":"print"},{"issue":"1","key":"181_27950506","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1677\/joe.1.07066","volume":"193","author":"Villicev","year":"2007","journal-title":"Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-0795","issn-type":"print"},{"issue":"10","key":"182_36727881","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1056\/NEJMoa0905633","volume":"362","author":"Ladenson","year":"2010","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"2","key":"183_35482406","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1677\/JOE-08-0539","volume":"203","year":"2009","journal-title":"Journal of Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-0795","issn-type":"print"},{"issue":"4","key":"184_41699780","first-page":"655","volume":"25","author":"Antonelli","year":"2011","journal-title":"Journal of biological regulators and homeostatic agents","ISSN":"https:\/\/id.crossref.org\/issn\/0393-974X","issn-type":"print"}],"container-title":["European Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/171\/4\/R137.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/171\/4\/R137.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:30:45Z","timestamp":1676392245000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/171\/4\/R137\/6661548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":183,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1530\/eje-14-0067","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10]]}}}