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A small number of studies have compared the effects of surgery and mineralocorticoid antagonists either on BP, on serum potassium levels, or on the incidence of cardiovascular and renal outcomes in patients with primary aldosteronism with or without an APA; these studies found no difference between the two therapeutic options. Mineralocorticoid receptor antagonists can be used as a maintenance treatment for patients with APAs, who are judged to be poor operative risks or who do not want to undergo surgery.<\/jats:p>","DOI":"10.1530\/eje-14-0585","type":"journal-article","created":{"date-parts":[[2014,10,15]],"date-time":"2014-10-15T06:32:11Z","timestamp":1413354731000},"page":"R125-R129","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":13,"title":["PROGRESS IN PRIMARY ALDOSTERONISM: Mineralocorticoid antagonist treatment for aldosterone-producing adenoma"],"prefix":"10.1093","volume":"172","author":[{"given":"Laurence","family":"Amar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lien","family":"Lorthioir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Francois","family":"Plouin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"3","key":"1_11097098","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1097\/00004872-200103000-00001","volume":"19","author":"Lim","year":"2001","journal-title":"Journal of hypertension","ISSN":"https:\/\/id.crossref.org\/issn\/0263-6352","issn-type":"print"},{"issue":"10","key":"2_35555854","doi-asserted-by":"publisher","first-page":"3623","DOI":"10.1210\/jc.2009-1399","volume":"94","year":"2009","journal-title":"Journal of Clinical Endocrinology &amp; 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