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Available evidence for routine prophylactic CND is not completely satisfactory. Our group's opinion, however, is that it reduces or even eliminates the need for repeat surgery in the central neck, better defines the extent (and stage) of the disease and provides a further argument against routine radioiodine ablation. Thus, PTC is becoming more and more a surgical disease that can be cured by optimized surgery alone in the majority of cases. Prophylactic CND, however, involves a higher risk for the parathyroid function and should be skilfully performed, preferably only on the same side as the primary tumour and preserving the cervical portion of the thymus.<\/jats:p>","DOI":"10.1530\/eje-15-0481","type":"journal-article","created":{"date-parts":[[2015,6,19]],"date-time":"2015-06-19T01:15:18Z","timestamp":1434676518000},"page":"R199-R206","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":15,"title":["THERAPY OF ENDOCRINE DISEASE: Central neck dissection: a step forward in the treatment of papillary thyroid cancer"],"prefix":"10.1093","volume":"173","author":[{"given":"Antonio","family":"Sitges-Serra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leyre","family":"Lorente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germ\u00e1n","family":"Mateu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan J","family":"Sancho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"2015102318231820000_173.6.R199.1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000925"},{"key":"2015102318231820000_173.6.R199.2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00348202"},{"key":"2015102318231820000_173.6.R199.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2007.09.002"},{"key":"2015102318231820000_173.6.R199.4","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(94)90321-2"},{"key":"2015102318231820000_173.6.R199.5","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440180017002"},{"key":"2015102318231820000_173.6.R199.6","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11031"},{"key":"2015102318231820000_173.6.R199.7","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900130"},{"key":"2015102318231820000_173.6.R199.8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00510.x"},{"key":"2015102318231820000_173.6.R199.9","doi-asserted-by":"crossref","unstructured":"Henry JF Gramatica L Denizot A Kvachenyuk A Puccini M Defechereux T . 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