{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:14:33Z","timestamp":1770275673587,"version":"3.49.0"},"reference-count":204,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>Endocrine complications are frequently observed in childhood cancer survivors (CCS). One of two CCS will experience at least one endocrine complication during the course of his\/her lifespan, most commonly as a late-effect of cancer treatments, especially radiotherapy and alkylating agent chemotherapy. Endocrine late-effects include impairments of the hypothalamus\/pituitary, thyroid and gonads, as well as decreased bone mineral density and metabolic derangements leading to obesity and\/or diabetes mellitus. A systematic approach where CCS are screened for endocrine late-effects based on their cancer history and treatment exposures may improve health outcomes by allowing the early diagnosis and treatment of these complications.<\/jats:p>","DOI":"10.1530\/eje-17-0054","type":"journal-article","created":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T01:25:42Z","timestamp":1486085142000},"page":"R183-R203","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":71,"title":["DIAGNOSIS OF ENDOCRINE DISEASE: Endocrine late-effects of childhood cancer and its treatments"],"prefix":"10.1093","volume":"176","author":[{"given":"Wassim","family":"Chemaitilly","sequence":"first","affiliation":[{"name":"1Departments of Pediatric Medicine-Division of Endocrinology"},{"name":"2Departments of Epidemiology and Cancer ControlSt Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurie E","family":"Cohen","sequence":"additional","affiliation":[{"name":"2Departments of Epidemiology and Cancer ControlSt Jude Children\u2019s Research Hospital, Memphis, Tennessee, USA"},{"name":"3Division of EndocrinologyBoston Children\u2019s Hospital, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"2017030317102329000_176.4.R183.1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21219"},{"key":"2017030317102329000_176.4.R183.2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.1953"},{"key":"2017030317102329000_176.4.R183.3","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-1043"},{"key":"2017030317102329000_176.4.R183.4","doi-asserted-by":"crossref","first-page":"4362","DOI":"10.1200\/JCO.2016.67.5025","article-title":"Prevalence and risk factors of early endocrine disorders in childhood brain tumor survivors: a nationwide, multicenter study","volume":"34","author":"Clement","year":"2016","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1515\/JPEM.2004.17.1.55","article-title":"Hypothalamic dysfunction after chemotherapy","volume":"17","author":"Rose","year":"2004","journal-title":"Journal of Pediatric Endocrinology and Metabolism"},{"key":"2017030317102329000_176.4.R183.6","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22120"},{"key":"2017030317102329000_176.4.R183.7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704481"},{"key":"2017030317102329000_176.4.R183.8","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-4085"},{"key":"2017030317102329000_176.4.R183.9","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/pbc.24121","article-title":"Imatinib mesylate causes growth deceleration in pediatric patients with chronic myelogenous leukemia","volume":"59","author":"Rastogi","year":"2012","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-4075"},{"key":"2017030317102329000_176.4.R183.11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.13.5293"},{"key":"2017030317102329000_176.4.R183.12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.7933"},{"key":"2017030317102329000_176.4.R183.13","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/neuonc\/nov302","article-title":"Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma","volume":"18","author":"Eaton","year":"2015","journal-title":"Neuro-Oncology"},{"key":"2017030317102329000_176.4.R183.14","doi-asserted-by":"crossref","first-page":"891","DOI":"10.4158\/EP10391.OR","article-title":"Pituitary hormone dysfunction after proton beam radiation therapy in children with brain tumors","volume":"17","author":"Viswanathan","year":"2011","journal-title":"Endocrine Practice"},{"key":"2017030317102329000_176.4.R183.15","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ijrobp.2014.05.051","article-title":"Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity","volume":"90","author":"Bishop","year":"2014","journal-title":"International Journal of Radiation Oncology, Biology, Physics"},{"key":"2017030317102329000_176.4.R183.16","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.6545"},{"key":"2017030317102329000_176.4.R183.17","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.9453"},{"key":"2017030317102329000_176.4.R183.18","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2013.06.007"},{"key":"2017030317102329000_176.4.R183.19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.9525"},{"key":"2017030317102329000_176.4.R183.20","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0022-3476(86)81027-7","article-title":"Greater susceptibility to hypothalamopituitary irradiation in younger children with acute lymphoblastic leukemia","volume":"108","author":"Brauner","year":"1986","journal-title":"Journal of Pediatrics"},{"key":"2017030317102329000_176.4.R183.21","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0022-3476(97)80022-4","article-title":"Contribution of growth hormone deficiency to the growth failure that follows bone marrow transplantation","volume":"130","author":"Brauner","year":"1997","journal-title":"Journal of Pediatrics"},{"key":"2017030317102329000_176.4.R183.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2007.07.002"},{"key":"2017030317102329000_176.4.R183.23","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(96)70119-1"},{"key":"2017030317102329000_176.4.R183.24","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705694"},{"key":"2017030317102329000_176.4.R183.25","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/sj.bmt.1705455","article-title":"Final height and gonad function after total body irradiation during childhood","volume":"38","author":"Couto-Silva","year":"2006","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.26","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.6.689"},{"key":"2017030317102329000_176.4.R183.27","first-page":"4109","article-title":"Final height of patients who underwent bone marrow transplantation for hematological disorders during childhood: a study by the Working Party for Late Effects-EBMT","volume":"93","author":"Cohen","year":"1999","journal-title":"Blood"},{"key":"2017030317102329000_176.4.R183.28","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1651-2227.1984.tb09908.x","article-title":"Incidence of anterior pituitary deficiency after radiotherapy at an early age: study in retinoblastoma","volume":"73","author":"Pomarede","year":"1984","journal-title":"Acta Paediatrica Scandinavica"},{"key":"2017030317102329000_176.4.R183.29","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/pbc.24280","article-title":"Long-term medical outcomes in survivors of extra-ocular retinoblastoma: the Memorial Sloan-Kettering Cancer Center (MSKCC) experience","volume":"60","author":"Friedman","year":"2013","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/cncr.25376","article-title":"Prognostic factors and long-term outcomes of childhood nasopharyngeal carcinoma","volume":"117","author":"Cheuk","year":"2011","journal-title":"Cancer"},{"key":"2017030317102329000_176.4.R183.31","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1002\/pbc.20310","article-title":"Long-term medical effects of childhood and adolescent rhabdomyosarcoma: a report from the childhood cancer survivor study","volume":"44","author":"Punyko","year":"2005","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejca.2015.10.064","article-title":"Endocrine disorders among long-term survivors of childhood head and neck rhabdomyosarcoma","volume":"54","author":"Clement","year":"2015","journal-title":"European Journal of Cancer"},{"key":"2017030317102329000_176.4.R183.33","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1002\/pbc.24397","article-title":"Growth failure in children with chronic myeloid leukemia receiving imatinib is due to disruption of GH\/IGF-1 axis","volume":"60","author":"Narayanan","year":"2013","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.34","doi-asserted-by":"crossref","first-page":"e0131192","DOI":"10.1371\/journal.pone.0131192","article-title":"Impact of long-term exposure to the tyrosine kinase inhibitor imatinib on the skeleton of growing rats","volume":"10","author":"Tauer","year":"2015","journal-title":"PLoS ONE"},{"key":"2017030317102329000_176.4.R183.35","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.11.3990"},{"key":"2017030317102329000_176.4.R183.36","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/pbc.22839","article-title":"Prevalence of advanced bone age in a cohort of patients who received cis-retinoic acid for high-risk neuroblastoma","volume":"56","author":"Hobbie","year":"2011","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.37","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0936-6555(05)80744-7","article-title":"The evolution of spinal growth after irradiation","volume":"3","author":"Clayton","year":"1991","journal-title":"Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.38","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80620-8"},{"key":"2017030317102329000_176.4.R183.39","doi-asserted-by":"publisher","DOI":"10.1210\/jc.79.2.537"},{"key":"2017030317102329000_176.4.R183.40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02676.x"},{"key":"2017030317102329000_176.4.R183.41","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)00427-M"},{"key":"2017030317102329000_176.4.R183.42","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70345-5"},{"key":"2017030317102329000_176.4.R183.43","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.1290511"},{"key":"2017030317102329000_176.4.R183.44","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00804.x"},{"key":"2017030317102329000_176.4.R183.45","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1159\/000452150","article-title":"& Drug and Therapeutics Committee and Ethics Committee of the Pediatric Endocrine Society. Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency","volume":"86","author":"Grimberg","year":"2016","journal-title":"Hormone Research in Paediatrics"},{"key":"2017030317102329000_176.4.R183.46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2005.02272.x"},{"key":"2017030317102329000_176.4.R183.47","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021094"},{"key":"2017030317102329000_176.4.R183.48","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-58-6-1043"},{"key":"2017030317102329000_176.4.R183.49","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301143280203"},{"key":"2017030317102329000_176.4.R183.50","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330350306"},{"key":"2017030317102329000_176.4.R183.51","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0160"},{"key":"2017030317102329000_176.4.R183.52","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1159\/000284393","article-title":"Effectiveness of rhGH treatment on adult height in GH-deficient childhood survivors of medulloblastoma","volume":"73","author":"Ciaccio","year":"2010","journal-title":"Hormone Research in Paediatrics"},{"key":"2017030317102329000_176.4.R183.53","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-0690"},{"key":"2017030317102329000_176.4.R183.54","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/cen.12964","article-title":"Central precocious puberty following the diagnosis and treatment of paediatric cancer and central nervous system tumours: presentation and long-term outcomes","volume":"84","author":"Chemaitilly","year":"2015","journal-title":"Clinical Endocrinology"},{"key":"2017030317102329000_176.4.R183.55","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2012.07.002"},{"key":"2017030317102329000_176.4.R183.56","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-1002"},{"key":"2017030317102329000_176.4.R183.57","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0656"},{"key":"2017030317102329000_176.4.R183.58","doi-asserted-by":"publisher","DOI":"10.1210\/jc.87.7.3136"},{"key":"2017030317102329000_176.4.R183.59","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0112"},{"key":"2017030317102329000_176.4.R183.60","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-4159"},{"key":"2017030317102329000_176.4.R183.61","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-1072"},{"key":"2017030317102329000_176.4.R183.62","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-1083"},{"key":"2017030317102329000_176.4.R183.63","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.01229.x"},{"key":"2017030317102329000_176.4.R183.64","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0800459"},{"key":"2017030317102329000_176.4.R183.65","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-2028"},{"key":"2017030317102329000_176.4.R183.66","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02582.x"},{"key":"2017030317102329000_176.4.R183.67","first-page":"43","article-title":"Precocious puberty following BMT","volume":"8","author":"Rossetti","year":"1991","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.68","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1996.02170310023003"},{"key":"2017030317102329000_176.4.R183.69","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1002\/cncr.24294","article-title":"Abnormal timing of menarche in survivors of central nervous system tumors: a report from the Childhood Cancer Survivor Study","volume":"115","author":"Armstrong","year":"2009","journal-title":"Cancer"},{"key":"2017030317102329000_176.4.R183.70","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1783"},{"key":"2017030317102329000_176.4.R183.71","doi-asserted-by":"crossref","first-page":"4315","DOI":"10.1200\/JCO.2016.70.1847","article-title":"Hypothalamic-pituitary axis dysfunction in survivors of childhood CNS tumors: importance of systematic follow-up and early endocrine consultation","volume":"34","author":"Chemaitilly","year":"2016","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.72","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1200\/JCO.1990.8.12.1981","article-title":"Effects of radiation on testicular function in long-term survivors of childhood acute lymphoblastic leukemia: a report from the Children Cancer Study Group","volume":"8","author":"Sklar","year":"1990","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.73","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900315)65:6<1303::AID-CNCR2820650608>3.0.CO;2-D"},{"key":"2017030317102329000_176.4.R183.74","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705612"},{"key":"2017030317102329000_176.4.R183.75","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1007\/s00432-016-2124-5","article-title":"Gonadal status in long-term male survivors of childhood cancer","volume":"142","author":"Brignardello","year":"2016","journal-title":"Journal of Cancer Research and Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.76","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1159\/000355577","article-title":"Endocrine complications and components of the metabolic syndrome in survivors of childhood malignant non-brain solid tumors","volume":"81","author":"Shalitin","year":"2014","journal-title":"Hormone Research in Paediatrics"},{"key":"2017030317102329000_176.4.R183.77","doi-asserted-by":"crossref","first-page":"3888","DOI":"10.1210\/jc.2016-2118","article-title":"Hormonal replacement in hypopituitarism in adults: an endocrine society clinical practice guideline","volume":"101","author":"Fleseriu","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"2017030317102329000_176.4.R183.78","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/nrendo.2015.112","article-title":"Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism \u2013 pathogenesis, diagnosis and treatment","volume":"11","author":"Boehm","year":"2015","journal-title":"Nature Reviews Endocrinology"},{"key":"2017030317102329000_176.4.R183.79","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1109290"},{"key":"2017030317102329000_176.4.R183.80","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.43.5511"},{"key":"2017030317102329000_176.4.R183.81","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.6938"},{"key":"2017030317102329000_176.4.R183.82","doi-asserted-by":"publisher","DOI":"10.1210\/jc.84.12.4472"},{"key":"2017030317102329000_176.4.R183.83","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1593"},{"key":"2017030317102329000_176.4.R183.84","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11864-016-0426-0","article-title":"Long-term effect of cranial radiotherapy on pituitary-hypothalamus area in childhood acute lymphoblastic leukemia survivors","volume":"17","author":"Follin","year":"2016","journal-title":"Current Treatment Options in Oncology"},{"key":"2017030317102329000_176.4.R183.85","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1182\/blood.V68.5.1129.1129","article-title":"Growth and development following marrow transplantation for leukemia","volume":"68","author":"Sanders","year":"1986","journal-title":"Blood"},{"key":"2017030317102329000_176.4.R183.86","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1002\/pbc.22208","article-title":"Adrenal function testing in pediatric cancer survivors","volume":"53","author":"Patterson","year":"2009","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.87","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/pbc.25291","article-title":"Ovarian function in survivors of childhood medulloblastoma: impact of reduced dose craniospinal irradiation and high-dose chemotherapy with autologous stem cell rescue","volume":"62","author":"Balachandar","year":"2014","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.88","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.9.3227"},{"key":"2017030317102329000_176.4.R183.89","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.6296"},{"key":"2017030317102329000_176.4.R183.90","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1200\/JCO.1997.15.6.2238","article-title":"Late effects of allogeneic bone marrow transplantation for children with acute myeloblastic leukemia in first complete remission: the impact of conditioning regimen without total-body irradiation \u2013 a report from the Societe Francaise de Greffe de Moelle","volume":"15","author":"Michel","year":"1997","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.91","first-page":"71","article-title":"Thyroid dysfunction following bone marrow transplantation using hyperfractionated radiation","volume":"15","author":"Boulad","year":"1995","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.92","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2010.210"},{"key":"2017030317102329000_176.4.R183.93","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31812f864d"},{"key":"2017030317102329000_176.4.R183.94","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702384"},{"key":"2017030317102329000_176.4.R183.95","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.ejca.2005.02.036","article-title":"de KJ & Vulsma T. Endocrine late effects from multi-modality treatment of neuroblastoma","volume":"41","author":"van Santen","year":"2005","journal-title":"European Journal of Cancer"},{"key":"2017030317102329000_176.4.R183.96","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0241"},{"key":"2017030317102329000_176.4.R183.97","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2015-1690"},{"key":"2017030317102329000_176.4.R183.98","doi-asserted-by":"crossref","first-page":"G17","DOI":"10.2741\/A714","article-title":"Endocrine complications of pediatric stem cell transplantation","volume":"6","author":"Sklar","year":"2001","journal-title":"Frontiers in Bioscience"},{"key":"2017030317102329000_176.4.R183.99","doi-asserted-by":"publisher","DOI":"10.1667\/RR2240.1"},{"key":"2017030317102329000_176.4.R183.100","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-11-0576"},{"key":"2017030317102329000_176.4.R183.101","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s11060-014-1712-y","article-title":"Evidence of high mortality in long term survivors of childhood medulloblastoma","volume":"122","author":"Ning","year":"2015","journal-title":"Journal of Neuro-Oncology"},{"key":"2017030317102329000_176.4.R183.102","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.08.9276"},{"key":"2017030317102329000_176.4.R183.103","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11362"},{"key":"2017030317102329000_176.4.R183.104","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/bmt.2015.63","article-title":"Secondary solid cancer screening following hematopoietic cell transplantation","volume":"50","author":"Inamoto","year":"2015","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.105","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/pbc.22082","article-title":"Risk of thyroid dysfunction and subsequent thyroid cancer among survivors of acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study","volume":"53","author":"Chow","year":"2009","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.106","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2001.01292.x"},{"key":"2017030317102329000_176.4.R183.107","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8652(199809)59:1<91::AID-AJH18>3.0.CO;2-4"},{"key":"2017030317102329000_176.4.R183.108","first-page":"469","article-title":"Treatment for acute lymphoblastic leukemia in children is associated with papillary carcinoma of thyroid, but not with thyroid disfunction","volume":"58","author":"Neves","year":"2006","journal-title":"Minerva Pediatrica"},{"key":"2017030317102329000_176.4.R183.109","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1089\/thy.2011.0464","article-title":"van der Steeg AF, Nieveen van Dijkum EJ & van Trotsenburg AS. Differentiated thyroid carcinoma after 131I-MIBG treatment for neuroblastoma during childhood: description of the first two cases","volume":"22","author":"van Santen","year":"2012","journal-title":"Thyroid"},{"key":"2017030317102329000_176.4.R183.110","first-page":"2885","article-title":"Therapeutic radiation at a young age is linked to secondary thyroid cancer. The Late Effects Study Group","volume":"51","author":"Tucker","year":"1991","journal-title":"Cancer Research"},{"key":"2017030317102329000_176.4.R183.111","doi-asserted-by":"publisher","DOI":"10.1210\/er.2011-0011"},{"key":"2017030317102329000_176.4.R183.112","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0460"},{"key":"2017030317102329000_176.4.R183.113","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2009.0110"},{"key":"2017030317102329000_176.4.R183.114","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0337"},{"key":"2017030317102329000_176.4.R183.115","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-2744"},{"key":"2017030317102329000_176.4.R183.116","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1200\/JCO.1999.17.5.1493","article-title":"Testicular function after cytotoxic chemotherapy: evidence of Leydig cell insufficiency","volume":"17","author":"Howell","year":"1999","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.117","doi-asserted-by":"publisher","DOI":"10.1136\/adc.76.3.190"},{"key":"2017030317102329000_176.4.R183.118","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.6.2446"},{"key":"2017030317102329000_176.4.R183.119","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80584-8"},{"key":"2017030317102329000_176.4.R183.120","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.ejca.2009.01.002","article-title":"Testicular function of survivors of childhood cancer: a comparative study between ifosfamide- and cyclophosphamide-based regimens","volume":"45","author":"Ridola","year":"2009","journal-title":"European Journal of Cancer"},{"key":"2017030317102329000_176.4.R183.121","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1398-2265.2004.00165.x","article-title":"Endocrine complications of high-dose therapy with stem cell transplantation","volume":"8","author":"Sanders","year":"2004","journal-title":"Pediatric Transplantation"},{"key":"2017030317102329000_176.4.R183.122","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199905)32:5<366::AID-MPO10>3.0.CO;2-7"},{"key":"2017030317102329000_176.4.R183.123","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1200\/JCO.1992.10.4.614","article-title":"Late effects of therapy in patients with paratesticular rhabdomyosarcoma. Intergroup Rhabdomyosarcoma Study Committee","volume":"10","author":"Heyn","year":"1992","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.124","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2354"},{"key":"2017030317102329000_176.4.R183.125","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.beem.2011.12.005","article-title":"Subclinical male hypogonadism","volume":"26","author":"Giannetta","year":"2012","journal-title":"Best Practice and Research Clinical Endocrinology and Metabolism"},{"key":"2017030317102329000_176.4.R183.126","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2013.08.010"},{"key":"2017030317102329000_176.4.R183.127","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702695"},{"key":"2017030317102329000_176.4.R183.128","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1703651"},{"key":"2017030317102329000_176.4.R183.129","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-01-0176"},{"key":"2017030317102329000_176.4.R183.130","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1182\/blood.V87.7.3045.bloodjournal8773045","article-title":"Pregnancies following high-dose cyclophosphamide with or without high-dose busulfan or total-body irradiation and bone marrow transplantation","volume":"87","author":"Sanders","year":"1996","journal-title":"Blood"},{"key":"2017030317102329000_176.4.R183.131","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2010.01058.x"},{"key":"2017030317102329000_176.4.R183.132","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70408-5"},{"key":"2017030317102329000_176.4.R183.133","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19961101)78:9<2020::AID-CNCR25>3.0.CO;2-Y"},{"key":"2017030317102329000_176.4.R183.134","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/MPH.0b013e3182a27c39","article-title":"Impaired testicular function after an ifosfamide-containing regimen for pediatric osteosarcoma: a case series and review of the literature","volume":"36","author":"Kenney","year":"2014","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"key":"2017030317102329000_176.4.R183.135","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010201)91:3<613::AID-CNCR1042>3.0.CO;2-R"},{"key":"2017030317102329000_176.4.R183.136","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1002\/pbc.24452","article-title":"Long-term follow-up of children with high-risk neuroblastoma: the ENSG5 trial experience","volume":"60","author":"Moreno","year":"2013","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.137","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705809"},{"key":"2017030317102329000_176.4.R183.138","doi-asserted-by":"crossref","first-page":"e1115","DOI":"10.1016\/j.fertnstert.2010.08.060","article-title":"Severe oligozoospermia in a young man with chronic myeloid leukemia on long-term treatment with imatinib started before puberty","volume":"95","author":"Mariani","year":"2011","journal-title":"Fertility and Sterility"},{"key":"2017030317102329000_176.4.R183.139","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200411113512024"},{"key":"2017030317102329000_176.4.R183.140","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2014.09.016"},{"key":"2017030317102329000_176.4.R183.141","doi-asserted-by":"publisher","DOI":"10.1080\/088800100276631"},{"key":"2017030317102329000_176.4.R183.142","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S2213-8587(15)00039-X","article-title":"Cancer treatment and gonadal function: experimental and established strategies for fertility preservation in children and young adults","volume":"3","author":"Anderson","year":"2015","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"2017030317102329000_176.4.R183.143","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.3288"},{"key":"2017030317102329000_176.4.R183.144","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0020"},{"key":"2017030317102329000_176.4.R183.145","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.5.495"},{"key":"2017030317102329000_176.4.R183.146","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djj243"},{"key":"2017030317102329000_176.4.R183.147","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/sj.bmt.1704324","article-title":"Pubertal development and final height after autologous bone marrow transplantation for acute lymphoblastic leukemia.","volume":"33","author":"Frisk","year":"2004","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.148","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/j.bbmt.2016.04.025","article-title":"Long-term follow-up after reduced-intensity conditioning and stem cell transplantation for childhood nonmalignant disorders","volume":"22","author":"Madden","year":"2016","journal-title":"Biology of Blood and Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.149","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1136\/adc.80.5.452","article-title":"Ovarian function after bone marrow transplantation performed before menarche","volume":"80","author":"Matsumoto","year":"1999","journal-title":"Archives of Disease in Childhood"},{"key":"2017030317102329000_176.4.R183.150","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(97)70345-7"},{"key":"2017030317102329000_176.4.R183.151","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1200\/JCO.1988.6.5.813","article-title":"Ovarian function following marrow transplantation for aplastic anemia or leukemia","volume":"6","author":"Sanders","year":"1988","journal-title":"Journal of Clinical Oncology"},{"key":"2017030317102329000_176.4.R183.152","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701569"},{"key":"2017030317102329000_176.4.R183.153","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08180.x"},{"key":"2017030317102329000_176.4.R183.154","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950210505"},{"key":"2017030317102329000_176.4.R183.155","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3109\/08880018.2015.1020178","article-title":"Age at birth of first child and fecundity of women survivors of childhood acute lymphoblastic leukemia (1987\u20132007): a study of the childhood cancer registry of the Rhone-Alpes Region in France (ARCERRA)","volume":"32","author":"Freycon","year":"2015","journal-title":"Pediatric Hematology and Oncology"},{"key":"2017030317102329000_176.4.R183.156","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr038"},{"key":"2017030317102329000_176.4.R183.157","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/pbc.23363","article-title":"Gonadal function and parenthood 20 years after treatment for childhood lymphoma: a cross-sectional study","volume":"59","author":"Hamre","year":"2012","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.158","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199910)33:4<362::AID-MPO4>3.0.CO;2-I"},{"key":"2017030317102329000_176.4.R183.159","doi-asserted-by":"publisher","DOI":"10.3109\/08880010903019344"},{"key":"2017030317102329000_176.4.R183.160","first-page":"123","article-title":"Problems during the long-term follow-up after surgery for pediatric solid malignancies","volume":"25","author":"Oue","year":"2015","journal-title":"European Journal of Pediatric Surgery"},{"key":"2017030317102329000_176.4.R183.161","doi-asserted-by":"crossref","first-page":"E112","DOI":"10.1210\/jc.2013-3595","article-title":"Primary ovarian insufficiency in children after treatment with 131I-metaiodobenzylguanidine for neuroblastoma: report of the first two cases","volume":"99","author":"Clement","year":"2014","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"2017030317102329000_176.4.R183.162","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.09.028"},{"key":"2017030317102329000_176.4.R183.163","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.fertnstert.2015.11.020","article-title":"Menses resumption after cancer treatment-induced amenorrhea occurs early or not at all","volume":"105","author":"Jacobson","year":"2016","journal-title":"Fertility and Sterility"},{"key":"2017030317102329000_176.4.R183.164","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s11914-014-0222-3","article-title":"Bone morbidity in childhood leukemia: epidemiology, mechanisms, diagnosis, and treatment","volume":"12","author":"Mostoufi-Moab","year":"2014","journal-title":"Current Osteoporosis Reports"},{"key":"2017030317102329000_176.4.R183.165","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-2393"},{"key":"2017030317102329000_176.4.R183.166","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-1396"},{"key":"2017030317102329000_176.4.R183.167","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1002\/pbc.25010","article-title":"Bone mineral density among long-term survivors of childhood acute lymphoblastic leukemia: results from the St. Jude Lifetime Cohort Study","volume":"61","author":"Gurney","year":"2014","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.168","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1927"},{"key":"2017030317102329000_176.4.R183.169","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704360"},{"key":"2017030317102329000_176.4.R183.170","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/j.bbmt.2011.10.006","article-title":"NCI, NHLBI\/PBMTC first international conference on late effects after pediatric hematopoietic cell transplantation: endocrine challenges-thyroid dysfunction, growth impairment, bone health, & reproductive risks","volume":"17","author":"Dvorak","year":"2011","journal-title":"Biology of Blood and Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.171","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701275"},{"key":"2017030317102329000_176.4.R183.172","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1499"},{"key":"2017030317102329000_176.4.R183.173","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00043426-199805000-00010","article-title":"Bone mineral density in young adult survivors of childhood cancer","volume":"20","author":"Aisenberg","year":"1998","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"key":"2017030317102329000_176.4.R183.174","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702131"},{"key":"2017030317102329000_176.4.R183.175","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1703149"},{"key":"2017030317102329000_176.4.R183.176","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704618"},{"key":"2017030317102329000_176.4.R183.177","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)80536-0"},{"key":"2017030317102329000_176.4.R183.178","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/bmt.2013.156","article-title":"Bone mineral deficits in recipients of hematopoietic cell transplantation: the impact of young age at transplant","volume":"49","author":"Petryk","year":"2014","journal-title":"Bone Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.179","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1002\/pbc.23300","article-title":"Bone density in post-pubertal adolescent survivors of childhood brain tumors","volume":"58","author":"Cohen","year":"2012","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.180","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11095"},{"key":"2017030317102329000_176.4.R183.181","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22546"},{"key":"2017030317102329000_176.4.R183.182","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021180"},{"key":"2017030317102329000_176.4.R183.183","doi-asserted-by":"publisher","DOI":"10.1210\/er.2013-1115"},{"key":"2017030317102329000_176.4.R183.184","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3332"},{"key":"2017030317102329000_176.4.R183.185","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.16.3527"},{"key":"2017030317102329000_176.4.R183.186","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1002\/pbc.24960","article-title":"Predictors of being overweight or obese in survivors of pediatric acute lymphoblastic leukemia (ALL)","volume":"61","author":"Zhang","year":"2014","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.187","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.bbmt.2016.08.019","article-title":"National institutes of health hematopoietic cell transplantation late effects initiative: the cardiovascular disease and associated risk factors working group report","volume":"23","author":"Armenian","year":"2017","journal-title":"Biology of Blood and Marrow Transplantation"},{"key":"2017030317102329000_176.4.R183.188","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00043426-200402000-00003","article-title":"Diabetes mellitus in long-term survivors of pediatric hematopoietic cell transplantation","volume":"26","author":"Hoffmeister","year":"2004","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"key":"2017030317102329000_176.4.R183.189","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02717-3"},{"key":"2017030317102329000_176.4.R183.190","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/pbc.24198","article-title":"Differential effects of radiotherapy on growth and endocrine function among acute leukemia survivors: a childhood cancer survivor study report","volume":"60","author":"Chow","year":"2013","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.191","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0128"},{"key":"2017030317102329000_176.4.R183.192","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/cen.12575","article-title":"Reduced beta-cell reserve and pancreatic volume in survivors of childhood acute lymphoblastic leukaemia treated with bone marrow transplantation and total body irradiation","volume":"82","author":"Wei","year":"2015","journal-title":"Clinical Endocrinology"},{"key":"2017030317102329000_176.4.R183.193","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1002\/pbc.25601","article-title":"Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes","volume":"62","author":"Wei","year":"2015","journal-title":"Pediatric Blood and Cancer"},{"key":"2017030317102329000_176.4.R183.194","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2013.218"},{"key":"2017030317102329000_176.4.R183.195","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.209"},{"key":"2017030317102329000_176.4.R183.196","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0052237"},{"key":"2017030317102329000_176.4.R183.197","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70323-6"},{"key":"2017030317102329000_176.4.R183.198","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2011.118"},{"key":"2017030317102329000_176.4.R183.199","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-030003"},{"key":"2017030317102329000_176.4.R183.200","doi-asserted-by":"crossref","first-page":"4825","DOI":"10.1210\/jc.2016-2126","article-title":"Diazoxide in children with obesity after hypothalamic-pituitary lesions: a randomized, placebo-controlled trial","volume":"101","author":"Brauner","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"2017030317102329000_176.4.R183.201","doi-asserted-by":"crossref","first-page":"417949","DOI":"10.1155\/2011\/417949","article-title":"Hypothalamic obesity following craniopharyngioma surgery: results of a pilot trial of combined diazoxide and metformin therapy","volume":"2011","author":"Hamilton","year":"2011","journal-title":"International Journal of Pediatric Endocrinology"},{"key":"2017030317102329000_176.4.R183.202","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1001\/archpedi.156.9.887","article-title":"The use of dextroamphetamine to treat obesity and hyperphagia in children treated for craniopharyngioma","volume":"156","author":"Mason","year":"2002","journal-title":"Archives of Pediatrics and Adolescent Medicine"},{"key":"2017030317102329000_176.4.R183.203","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1002\/oby.21493","article-title":"A 52-week pilot study of the effects of exenatide on body weight in patients with hypothalamic obesity","volume":"24","author":"Lomenick","year":"2016","journal-title":"Obesity"},{"key":"2017030317102329000_176.4.R183.204","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/MED.0000000000000264","article-title":"Update on childhood craniopharyngiomas","volume":"23","author":"Cohen","year":"2016","journal-title":"Current Opinion in Endocrinology, Diabetes and Obesity"}],"container-title":["European Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/176\/4\/R183.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1530\/EJE-17-0054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:10:33Z","timestamp":1676391033000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/176\/4\/R183\/6655126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":204,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1530\/eje-17-0054","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}