{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T03:53:02Z","timestamp":1769053982686,"version":"3.49.0"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,10]]},"abstract":"\nObjective<\/jats:title>\nAdrenal vein sampling (AVS) represents the current diagnostic standard for subtype differentiation in primary aldosteronism (PA). However, AVS has its drawbacks. It is invasive, expensive, requires an experienced interventional radiologist and comes with radiation exposure. However, exact radiation exposure of patients undergoing AVS has never been examined.<\/jats:p>\n<\/jats:sec>\n\nDesign and methods<\/jats:title>\nWe retrospectively analyzed radiation exposure of 656 AVS performed between 1999 and 2017 at four university hospitals. The primary outcomes were dose area product (DAP) and fluoroscopy time (FT). Consecutively the effective dose (ED) was approximately calculated.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\nMedian DAP was found to be 32.5\u2009Gy*cm2<\/jats:sup> (0.3\u20133181) and FT 18\u2009min (0.3\u2013184). The calculated ED was 6.4\u2009mSv (0.1\u2013636). Remarkably, values between participating centers highly varied: Median DAP ranged from 16 to 147\u2009Gy*cm2<\/jats:sup>, FT from 16 to 27\u2009min, and ED from 3.2 to 29\u2009mSv. As main reason for this variation, differences regarding AVS protocols between centers could be identified, such as number of sampling locations, frames per second and the use of digital subtraction angiographies.<\/jats:p>\n<\/jats:sec>\n\nConclusion<\/jats:title>\nThis first systematic assessment of radiation exposure in AVS not only shows fairly high values for patients, but also states notable differences among the centers. Thus, we not only recommend taking into account the risk of radiation exposure, when referring patients to undergo AVS, but also to establish improved standard operating procedures to prevent unnecessary radiation exposure.<\/jats:p>\n<\/jats:sec>","DOI":"10.1530\/eje-18-0328","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T13:15:15Z","timestamp":1533129315000},"page":"261-267","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":31,"title":["Radiation exposure of adrenal vein sampling: a German Multicenter Study"],"prefix":"10.1093","volume":"179","author":[{"given":"C T","family":"Fuss","sequence":"first","affiliation":[{"name":"1Department of Medicine I, Division of Endocrinology and Diabetology, University Hospital, University of W\u00fcrzburg, W\u00fcrzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Treitl","sequence":"additional","affiliation":[{"name":"2Department of Clinical Radiology, Ludwig-Maximilians-University, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Rayes","sequence":"additional","affiliation":[{"name":"3Department of General, Visceral and Transplant Surgery, University Hospital Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Podrabsky","sequence":"additional","affiliation":[{"name":"4Department of Radiology, Charit\u00e9 Campus Virchow Klinikum, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W K","family":"Fenske","sequence":"additional","affiliation":[{"name":"5Leipzig University Medical Center, Integrated Center for Research and Treatment Adiposity Diseases, Leipzig, Germany"},{"name":"6Internal Medicine (Endocrinology and Nephrology), University of Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Heinrich","sequence":"additional","affiliation":[{"name":"7Department of Endocrinology, Ludwig-Maximilians-University, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Reincke","sequence":"additional","affiliation":[{"name":"7Department of Endocrinology, Ludwig-Maximilians-University, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T-O","family":"Petersen","sequence":"additional","affiliation":[{"name":"8Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Fassnacht","sequence":"additional","affiliation":[{"name":"1Department of Medicine I, Division of Endocrinology and Diabetology, University Hospital, University of W\u00fcrzburg, W\u00fcrzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Quinkler","sequence":"additional","affiliation":[{"name":"9Endokrinologie in Charlottenburg, Endokrinologie Praxis am Stuttgarter Platz, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Kickuth","sequence":"additional","affiliation":[{"name":"10Department of Radiology, University Hospital W\u00fcrzburg, W\u00fcrzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Hahner","sequence":"additional","affiliation":[{"name":"1Department of Medicine I, Division of Endocrinology and Diabetology, University Hospital, University of W\u00fcrzburg, W\u00fcrzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"ref311","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline","volume":"101","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref251","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1210\/jc.2015-3405","article-title":"Prevalence of malignancies in patients with primary aldosteronism","volume":"101","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref321","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1210\/jc.2008-2116","article-title":"Cardiovascular and cerebrovascular comorbidities of hypokalemic and normokalemic primary aldosteronism: results of the German Conn\u2019s Registry","volume":"94","year":"2009","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref491","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1088\/0031-9155\/37\/11\/008","article-title":"Estimation of effective dose to the patient during medical x-ray examinations from measurements of the dose-area product","volume":"37","year":"1992","journal-title":"Physics in Medicine and Biology"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1161\/HYPERTENSIONAHA.114.04812","article-title":"Influence of diagnostic criteria on the interpretation of adrenal vein sampling","volume":"65","year":"2015","journal-title":"Hypertension"},{"key":"ref161","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1055\/s-0043-120524","article-title":"The SPARTACUS trial: controversies and unresolved issues","volume":"49","year":"2017","journal-title":"Hormone and Metabolic Research"},{"key":"ref231","doi-asserted-by":"publisher","first-page":"200920","DOI":"10.1016\/j.jvir.2009.04.037","article-title":"Guidelines for patient radiation dose management of and https org","journal-title":"Journal Vascular Interventional Radiology"},{"key":"ref501","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1148\/radiol.2481071451","article-title":"Effective doses in radiology and diagnostic nuclear medicine: a catalog","volume":"248","year":"2008","journal-title":"Radiology"},{"key":"ref551","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1210\/jc.2015-3405","article-title":"Prevalence of malignancies in patients with primary aldosteronism","volume":"101","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","article-title":"A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients","volume":"48","year":"2006","journal-title":"Journal of the American College of Cardiology"},{"key":"ref441","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/HYPERTENSIONAHA.117.09294","article-title":"Adrenal vein sampling is the preferred method to select patients with primary aldosteronism for adrenalectomy: con side of the argument","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref541","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.icrp.2012.02.001","article-title":"ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs \u2013 threshold doses for tissue reactions in a radiation protection context","volume":"41","year":"2012","journal-title":"Annals of the ICRP"},{"key":"ref581","first-page":"4563218760352","article-title":"Improved technical success and radiation safety of adrenal vein sampling using rapid, semi-quantitative point-of-care cortisol measurement","year":"2018","journal-title":"Annals of Clinical Biochemistry"},{"key":"ref301","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nrendo.2011.223","article-title":"Primary aldosteronism in 2011: towards a better understanding of causation and consequences","volume":"8","year":"2012","journal-title":"Nature Reviews Endocrinology"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nrendo.2011.223","article-title":"Primary aldosteronism in 2011: towards a better understanding of causation and consequences","volume":"8","year":"2012","journal-title":"Nature Reviews Endocrinology"},{"key":"ref421","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1365-2265.2009.03714.x","article-title":"Adrenal vein sampling for primary aldosteronism: time for a reality check","volume":"72","year":"2010","journal-title":"Clinical Endocrinology"},{"key":"ref391","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/HYPERTENSIONAHA.113.02097","article-title":"An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism","volume":"63","year":"2014","journal-title":"Hypertension"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"329","DOI":"10.7326\/0003-4819-151-5-200909010-00007","article-title":"Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism","volume":"151","year":"2009","journal-title":"Annals of Internal Medicine"},{"key":"ref461","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1055\/s-0043-120524","article-title":"The SPARTACUS trial: controversies and unresolved issues","volume":"49","year":"2017","journal-title":"Hormone and Metabolic Research"},{"key":"ref471","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1210\/jc.2011-1537","article-title":"Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref431","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1161\/HYPERTENSIONAHA.117.09295","article-title":"Adrenal vein sampling is the preferred method to select patients with primary aldosteronism for adrenalectomy: pro side of the argument","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref381","doi-asserted-by":"crossref","first-page":"329","DOI":"10.7326\/0003-4819-151-5-200909010-00007","article-title":"Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism","volume":"151","year":"2009","journal-title":"Annals of Internal Medicine"},{"key":"ref131","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1161\/HYPERTENSIONAHA.117.09295","article-title":"Adrenal vein sampling is the preferred method to select patients with primary aldosteronism for adrenalectomy: pro side of the argument","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref561","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00270-009-9756-7","article-title":"Occupational radiation protection in interventional radiology: a joint guideline of the Cardiovascular and Interventional Radiology Society of Europe and the Society of Interventional Radiology","volume":"33","year":"2010","journal-title":"CardioVascular and Interventional Radiology"},{"key":"ref411","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1210\/jc.2011-2830","article-title":"The Adrenal Vein Sampling International Study (AVIS) for identifying the major subtypes of primary aldosteronism","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref451","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2213-8587(16)30100-0","article-title":"Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial","volume":"4","year":"2016","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"ref281","first-page":"4563218760352","article-title":"Improved technical success and radiation safety of adrenal vein sampling using rapid, semi-quantitative point-of-care cortisol measurement","year":"2018","journal-title":"Annals of Clinical Biochemistry"},{"key":"ref591","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jacc.2007.03.040","article-title":"Obesity is a major determinant of radiation dose in patients undergoing pulmonary vein isolation for atrial fibrillation","volume":"50","year":"2007","journal-title":"Journal of the American College of Cardiology"},{"key":"ref211","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1148\/radiol.2532082010","article-title":"Radiologic and nuclear medicine studies in the United States and worldwide: frequency, radiation dose, and comparison with other radiation sources \u2013 1950\u20132007","volume":"253","year":"2009","journal-title":"Radiology"},{"key":"ref261","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s00270-009-9756-7","article-title":"Occupational radiation protection in interventional radiology: a joint guideline of the Cardiovascular and Interventional Radiology Society of Europe and the Society of Interventional Radiology","volume":"33","year":"2010","journal-title":"CardioVascular and Interventional Radiology"},{"key":"ref531","doi-asserted-by":"publisher","first-page":"200920","DOI":"10.1016\/j.jvir.2009.04.037","article-title":"Guidelines for patient radiation dose management of and https org","journal-title":"Journal Vascular Interventional Radiology"},{"key":"ref201","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1148\/radiol.2481071451","article-title":"Effective doses in radiology and diagnostic nuclear medicine: a catalog","volume":"248","year":"2008","journal-title":"Radiology"},{"key":"ref511","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1148\/radiol.2532082010","article-title":"Radiologic and nuclear medicine studies in the United States and worldwide: frequency, radiation dose, and comparison with other radiation sources \u2013 1950\u20132007","volume":"253","year":"2009","journal-title":"Radiology"},{"key":"ref481","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1161\/HYPERTENSIONAHA.117.09975","article-title":"Targeting CXCR4 (CXC Chemokine Receptor Type 4) for molecular imaging of aldosterone-producing adenoma","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S2213-8587(17)30135-3","article-title":"Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort","volume":"5","year":"2017","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1210\/jc.2008-2116","article-title":"Cardiovascular and cerebrovascular comorbidities of hypokalemic and normokalemic primary aldosteronism: results of the German Conn\u2019s Registry","volume":"94","year":"2009","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref111","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1210\/jc.2011-2830","article-title":"The Adrenal Vein Sampling International Study (AVIS) for identifying the major subtypes of primary aldosteronism","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1210\/jc.2003-031337","article-title":"Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents","volume":"89","year":"2004","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref151","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2213-8587(16)30100-0","article-title":"Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial","volume":"4","year":"2016","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"ref171","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1210\/jc.2011-1537","article-title":"Evaluation of the sensitivity and specificity of (11)C-metomidate positron emission tomography (PET)-CT for lateralizing aldosterone secretion by Conn's adenomas","volume":"97","year":"2012","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref181","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1161\/HYPERTENSIONAHA.117.09975","article-title":"Targeting CXCR4 (CXC Chemokine Receptor Type 4) for molecular imaging of aldosterone-producing adenoma","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref341","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1530\/EJE-15-0450","article-title":"Increased prevalence of diabetes mellitus and the metabolic syndrome in patients with primary aldosteronism of the German Conn\u2019s Registry","volume":"173","year":"2015","journal-title":"European Journal of Endocrinology"},{"key":"ref141","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1161\/HYPERTENSIONAHA.117.09294","article-title":"Adrenal vein sampling is the preferred method to select patients with primary aldosteronism for adrenalectomy: con side of the argument","volume":"71","year":"2018","journal-title":"Hypertension"},{"key":"ref401","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1161\/HYPERTENSIONAHA.110.168484","article-title":"Adrenal venous sampling: evaluation of the German Conn\u2019s registry","volume":"57","year":"2011","journal-title":"Hypertension"},{"key":"ref361","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S2213-8587(17)30135-3","article-title":"Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort","volume":"5","year":"2017","journal-title":"Lancet Diabetes and Endocrinology"},{"key":"ref271","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1530\/EJE-11-0287","article-title":"Adrenal vein sampling using rapid cortisol assays in primary aldosteronism is useful in centers with low success rates","volume":"165","year":"2011","journal-title":"European Journal of Endocrinology"},{"key":"ref91","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/HYPERTENSIONAHA.113.02097","article-title":"An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism","volume":"63","year":"2014","journal-title":"Hypertension"},{"key":"ref371","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1161\/HYPERTENSIONAHA.114.04812","article-title":"Influence of diagnostic criteria on the interpretation of adrenal vein sampling","volume":"65","year":"2015","journal-title":"Hypertension"},{"key":"ref121","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1365-2265.2009.03714.x","article-title":"Adrenal vein sampling for primary aldosteronism: time for a reality check","volume":"72","year":"2010","journal-title":"Clinical Endocrinology"},{"key":"ref331","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1210\/jc.2003-031337","article-title":"Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents","volume":"89","year":"2004","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1530\/EJE-15-0450","article-title":"Increased prevalence of diabetes mellitus and the metabolic syndrome in patients with primary aldosteronism of the German Conn\u2019s Registry","volume":"173","year":"2015","journal-title":"European Journal of Endocrinology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society Clinical Practice Guideline","volume":"101","year":"2016","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"ref571","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1530\/EJE-11-0287","article-title":"Adrenal vein sampling using rapid cortisol assays in primary aldosteronism is useful in centers with low success rates","volume":"165","year":"2011","journal-title":"European Journal of Endocrinology"},{"key":"ref101","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1161\/HYPERTENSIONAHA.110.168484","article-title":"Adrenal venous sampling: evaluation of the German Conn\u2019s registry","volume":"57","year":"2011","journal-title":"Hypertension"},{"key":"ref191","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1088\/0031-9155\/37\/11\/008","article-title":"Estimation of effective dose to the patient during medical x-ray examinations from measurements of the dose-area product","volume":"37","year":"1992","journal-title":"Physics in Medicine and Biology"},{"key":"ref291","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jacc.2007.03.040","article-title":"Obesity is a major determinant of radiation dose in patients undergoing pulmonary vein isolation for atrial fibrillation","volume":"50","year":"2007","journal-title":"Journal of the American College of Cardiology"},{"key":"ref351","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","article-title":"A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients","volume":"48","year":"2006","journal-title":"Journal of the American College of Cardiology"},{"key":"ref241","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.icrp.2012.02.001","article-title":"ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs \u2013 threshold doses for tissue reactions in a radiation protection context","volume":"41","year":"2012","journal-title":"Annals of the ICRP"}],"container-title":["European Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/179\/4\/EJE-18-0328.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1530\/EJE-18-0328","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:12:12Z","timestamp":1676391132000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/179\/4\/261\/6655442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":58,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1530\/eje-18-0328","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}