{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:32:52Z","timestamp":1776990772797,"version":"3.51.4"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n<jats:title>Context<\/jats:title>\n<jats:p>Cabergoline has been shown to have some effect in the treatment of moderate Cushing\u2019s disease, but its effectiveness in Cushing\u2019s syndrome of ectopic or occult origin remains to be investigated.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Case series<\/jats:title>\n<jats:p>In this case series, cabergoline was used in combination with steroidogenesis inhibitors in nine patients with severe Cushing\u2019s syndrome of ectopic or occult origin. Cabergoline\u2019s effectiveness enabled rapid withdrawal of the steroidogenesis inhibitors and long-term control of the hypercortisolism in three of the cases.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Review of the literature<\/jats:title>\n<jats:p>In the literature, we found only 11 cases of ectopic or occult Cushing\u2019s syndrome treated with dopamine receptor agonists, alone or in combination. Yet of these 11 cases, 10 responded.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Although limited, the existing experience highlights the potential value of cabergoline in the treatment of ectopic or occult Cushing\u2019s syndrome.<\/jats:p>\n<\/jats:sec>","DOI":"10.1530\/eje-18-1014","type":"journal-article","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T15:59:57Z","timestamp":1556812797000},"page":"K1-K9","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":10,"title":["Cabergoline in severe ectopic or occult Cushing\u2019s syndrome"],"prefix":"10.1093","volume":"181","author":[{"given":"Mirela Diana","family":"Ilie","sequence":"first","affiliation":[{"name":"1Endocrinology Department, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"},{"name":"2Lyon 1 University, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00e9ronique","family":"Raverot","sequence":"additional","affiliation":[{"name":"3Biochemistry Laboratory Department, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Tronc","sequence":"additional","affiliation":[{"name":"2Lyon 1 University, Lyon, France"},{"name":"4Thoracic Surgery Department, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Vasiljevic","sequence":"additional","affiliation":[{"name":"2Lyon 1 University, Lyon, France"},{"name":"5Department of Pathology, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7oise","family":"Borson-Chazot","sequence":"additional","affiliation":[{"name":"1Endocrinology Department, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"},{"name":"2Lyon 1 University, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9rald","family":"Raverot","sequence":"additional","affiliation":[{"name":"1Endocrinology Department, \u2018Groupement Hospitalier Est\u2019 Hospices Civils de Lyon, Lyon, France"},{"name":"2Lyon 1 University, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"ref261","doi-asserted-by":"crossref","first-page":"829","DOI":"10.4158\/EP09286.CR","article-title":"Long-term management with octreotide or cabergoline in ectopic corticotropin hypersecretion: case report and literature review","volume":"16","year":"2010","journal-title":"Endocrine 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