{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:24:03Z","timestamp":1762899843630},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":["eje.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>Germline mutations in the chloride channel gene <jats:italic>CLCN2<\/jats:italic> have been described as cause of familial hyperaldosteronism type II. In this issue, Dutta and colleagues in a groundbreaking study identify a somatic (tumor-specific) <jats:italic>CLCN2<\/jats:italic> mutation in an aldosterone-producing adenoma, expanding the disease spectrum associated with <jats:italic>CLCN2<\/jats:italic> mutations.<\/jats:p>","DOI":"10.1530\/eje-19-0688","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T10:44:41Z","timestamp":1570185881000},"page":"C21-C22","update-policy":"http:\/\/dx.doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":3,"title":["CLCN2 clicks with aldosterone-producing adenomas, too!"],"prefix":"10.1093","volume":"181","author":[{"given":"Ute I","family":"Scholl","sequence":"first","affiliation":[{"name":"1Department of Nephrology and Medical Intensive Care, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"},{"name":"2Berlin Institute of Health (BIH), Berlin, Germany"},{"name":"3Charit\u00e9 \u2014 Universit\u00e4tsmedizin Berlin, BCRT - BIH Center for Regenerative Therapies, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","container-title":["European Journal of Endocrinology"],"original-title":[],"link":[{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/181\/5\/EJE-19-0688.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eje.bioscientifica.com\/view\/journals\/eje\/181\/5\/EJE-19-0688.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T16:13:55Z","timestamp":1676391235000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ejendo\/article\/181\/5\/C21\/6654057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":0,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.1530\/eje-19-0688","relation":{},"ISSN":["0804-4643","1479-683X"],"issn-type":[{"value":"0804-4643","type":"print"},{"value":"1479-683X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}