{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T10:10:10Z","timestamp":1786702210379,"version":"build-2736575974"},"reference-count":20,"publisher":"Bioscientifica","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["eor.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Partial wrist denervation can be performed by isolated posterior interosseous nerve (PIN) or combined PIN plus (+) anterior interosseous nerve (AIN) neurectomy procedures.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>The purpose of the current systematic review is to investigate any differences in clinical outcomes and failures in patients undergoing AIN\u2009+\u2009PIN vs isolated PIN neurectomy.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>A review of the English Literature was performed on Medline, WOS and Scopus according to PRISMA protocol combining \u2018wrist denervation\u2019, \u2018PIN neurectomy\u2019, \u2018AIN neurectomy\u2019, anterior interosseous nerve neurectomy\u2019 and \u2018posterior interosseous nerve neurectomy\u2019. Studies were assessed with a modified Coleman Methodology Score (CMS). The primary outcome for meta-analysis was \u2018Failures\u2019, including all patients who have required a second surgery or those who are left with pain (defined as \u2018bad\u2019).<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>\n                          Overall, 10 studies totalling 347 wrists were included in this systematic review, with a \u2018moderate\u2019 CMS. The isolated PIN neurectomy technique showed a 15.1% pooled failure rate at a median follow-up of 22 months, while the combined AIN+PIN denervation had a pooled failure rate of 23.6% at a follow-up with a median of 29 months. The combined analysis of both procedures did not show significantly better results in favour of either technique, with a general failure rate of 21.6% (\n                          <jats:italic>P<\/jats:italic>\n                          \u2009=\u20090.0501).\n                        <\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Partial denervation for chronic wrist pain is a salvage procedure that leads to an overall success of 78.4% for pain relief, with no substantial complications. Apparently, performing the neurectomy also of the AIN does not offer greater advantages compared to the isolated PIN neurectomy.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>","DOI":"10.1530\/eor-22-0089","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T08:07:48Z","timestamp":1678781268000},"page":"110-116","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-16","source":"Crossref","is-referenced-by-count":7,"title":["Does anterior plus posterior interosseus neurectomy lead to better outcomes than isolated posterior interosseus denervation in the treatment of chronic wrist pain? A systematic review of the literature and meta-analysis"],"prefix":"10.1530","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7766-0806","authenticated-orcid":true,"given":"Andrea","family":"Fidanza","sequence":"first","affiliation":[{"name":"Unit of Orthopaedics and Traumatology - Department of life, Health & Environmental Sciences, University of L\u2019Aquila, Italy"},{"name":"Hand Unit, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Necozione","sequence":"additional","affiliation":[{"name":"Unit of Clinical Epidemiology - Department of life, Health & Environmental Sciences, University of L\u2019Aquila, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Garagnani","sequence":"additional","affiliation":[{"name":"Hand Unit, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Faculty of Life Sciences and Medicine, King\u2019s College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Journal of the American Academy of Orthopaedic Surgeons","first-page":"45","article-title":"Evaluation of chronic wrist pain","volume":"8","author":"Nagle","year":"2000","unstructured":"Nagle DJEvaluation of chronic wrist pain. 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(https:\/\/doi.org\/10.1016\/j.jhsa.2011.07.027)"}],"container-title":["EFORT Open Reviews"],"original-title":[],"link":[{"URL":"https:\/\/eor.bioscientifica.com\/view\/journals\/eor\/8\/3\/EOR-22-0089.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/eor.bioscientifica.com\/downloadpdf\/journals\/eor\/8\/3\/EOR-22-0089.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/eor.bioscientifica.com\/downloadpdf\/journals\/eor\/8\/3\/EOR-22-0089.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:50:51Z","timestamp":1784555451000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.bioscientifica.com\/eor\/article\/8\/3\/110-116\/2536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":20,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1530\/eor-22-0089","relation":{},"ISSN":["2058-5241"],"issn-type":[{"value":"2058-5241","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]}}}