{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:17:34Z","timestamp":1784557054429,"version":"3.55.0"},"reference-count":70,"publisher":"Bioscientifica","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["eor.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Primary bone tumors of the fibula are rare. Distal fibular resection has a significant impact on ankle biomechanics and gait, possibly leading to complications such as ankle instability, valgus deformity, and degenerative changes. Question: Is there a need for reconstructive surgery after distal fibular resection, and what reconstructive procedures are available?<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>The review is registered with the PROSPERO International Register of Systematic Reviews. Inclusion criteria consisted of all levels of evidence, human studies, patients of all ages and genders, publication in English, and resection of the distal portion of the fibula due to tumor pathology. The reviewers defined four different categories of interest by method of treatment. Additional articles of interest during full-text review were also added.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>The initial search resulted with a total of 2958 records. After screening, a total of 50 articles were included in the study. Articles were divided into \u2018No reconstruction\u2019, \u2018Soft tissue reconstruction\u2019, \u2018Bone and soft tissue reconstruction\u2019, and \u2018Arthrodesis, arthroplasty or other reconstruction options\u2019 groups.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Limb salvage surgery should be followed by reconstruction in order to avoid complications. Soft tissue reconstructions should always be considered to stabilize the joint after fibular resection. Bone reconstruction with reversed vascularized fibula is the preferred technique in young patients and in cases of bone defects more than 3 cm, while arthrodesis should be considered in adult patients. Whenever possible for oncologic reason, if a residual peroneal malleolus could be preserved, we prefer augmentation with a sliding ipsilateral fibular graft.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:sec>","DOI":"10.1530\/eor-23-0159","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T08:18:46Z","timestamp":1717402726000},"page":"503-516","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-16","source":"Crossref","is-referenced-by-count":4,"title":["Reconstructive surgery after distal fibular resection due to bone tumors: a technical report on surgical strategies and results from the PROSPERO international register of systematic reviews"],"prefix":"10.1530","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8823-448X","authenticated-orcid":true,"given":"Andrea","family":"Angelini","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Bohacek","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Salata, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihovil","family":"Plecko","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Salata, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8517-0057","authenticated-orcid":true,"given":"Carlo","family":"Biz","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Trovarelli","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariachiara","family":"Cerchiaro","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Di Rubbo","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9617-9882","authenticated-orcid":true,"given":"Pietro","family":"Ruggieri","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Journal of Foot and Ankle Surgery","first-page":"282","article-title":"Review of foot tumors seen in a university tumor institute","volume":"53","author":"Ruggieri","year":"2014","unstructured":"Ruggieri PAngelini AJorge FDMaraldi M & Giannini S. Review of foot tumors seen in a university tumor institute. Journal of Foot and Ankle Surgery201453282\u2013285. (https:\/\/doi.org\/10.1053\/j.jfas.2014.01.015)"},{"key":"bib2","series-title":"Radiologic Clinics of North America","first-page":"917","article-title":"Bone and soft tissue tumors about the foot and ankle","volume":"56","author":"Murai","year":"2018","unstructured":"Murai NOTeniola OWang WL & Amini B. Bone and soft tissue tumors about the foot and ankle. Radiologic Clinics of North America201856917\u2013934. (https:\/\/doi.org\/10.1016\/j.rcl.2018.06.010)"},{"key":"bib3","series-title":"Dahlin\u2019s Bone Tumors: General Aspects and Data on 10,165 Cases","author":"Unni","year":"2010","unstructured":"Unni KK & Inwards CY. Dahlin\u2019s Bone Tumors: General Aspects and Data on 10,165 Cases. Philadelphia: Lippincott Williams & Wilkins2010."},{"key":"bib4","series-title":"Journal of Orthopaedic Surgery","first-page":"2309499018798180","article-title":"The incidence and distribution of primary fibula tumors and tumor-like lesions: a 35-year experience","volume":"26","author":"Arikan","year":"2018","unstructured":"Arikan YMisir AOzer DKizkapan TBYildiz KISaygili MSIncesoy MADincel YMGursu SS & Sahin V. The incidence and distribution of primary fibula tumors and tumor-like lesions: a 35-year experience. Journal of Orthopaedic Surgery2018262309499018798180. (https:\/\/doi.org\/10.1177\/2309499018798180)"},{"key":"bib5","series-title":"Journal of Bone and Joint Surgery","first-page":"559","article-title":"Distal fibulectomy for Ewing\u2019s sarcoma","volume":"76","author":"Norman-Taylor","year":"1994","unstructured":"Norman-Taylor FHSweetnam DI & Fixsen JA. Distal fibulectomy for Ewing\u2019s sarcoma. Journal of Bone and Joint Surgery199476559\u2013562. (https:\/\/doi.org\/10.1302\/0301-620X.76B4.8027140)"},{"key":"bib6","series-title":"Malaysian Orthopaedic Journal","first-page":"64","article-title":"Primary osteosarcoma of the distal fibula treated with distal fibulectomy with a five-year follow-up: a case report","volume":"11","author":"Saadon","year":"2017","unstructured":"Saadon IAmit BZolquarnian A & Muhamad F. Primary osteosarcoma of the distal fibula treated with distal fibulectomy with a five-year follow-up: a case report. Malaysian Orthopaedic Journal20171164\u201367. (https:\/\/doi.org\/10.5704\/MOJ.1707.010)"},{"key":"bib7","series-title":"BMC Research Notes","first-page":"769","article-title":"Ankle ligament reconstruction after wide resection of the osteosarcoma of the distal fibula: a case report","volume":"10","author":"Vaseenon","year":"2017","unstructured":"Vaseenon TSaengsin JKaminta APattamapaspong NSettakorn J & Pruksakorn D. Ankle ligament reconstruction after wide resection of the osteosarcoma of the distal fibula: a case report. BMC Research Notes201710769. (https:\/\/doi.org\/10.1186\/s13104-017-3097-4)"},{"key":"bib8","series-title":"Foot and Ankle International","first-page":"325","article-title":"Distal lower extremity sarcomas: frequency of occurrence and patient survival rate","volume":"25","author":"Zeytoonjian","year":"2004","unstructured":"Zeytoonjian TMankin HJGebhardt MC & Hornicek FJ. Distal lower extremity sarcomas: frequency of occurrence and patient survival rate. Foot and Ankle International200425325\u2013330. (https:\/\/doi.org\/10.1177\/107110070402500509)"},{"key":"bib9","series-title":"Foot and Ankle International","first-page":"22","article-title":"Limb salvage in Ewing\u2019s sarcoma of the distal lower extremity","volume":"29","author":"San-Julian","year":"2008","unstructured":"San-Julian MDuart Jde Rada PD & Sierrasesumaga L. Limb salvage in Ewing\u2019s sarcoma of the distal lower extremity. Foot and Ankle International20082922\u201328. (https:\/\/doi.org\/10.3113\/FAI.2008.0022)"},{"key":"bib10","series-title":"Microsurgery","first-page":"490","article-title":"Ankle joint salvage surgery with an ipsilateral mid-fibula osteocutaneous free flap and contralateral anterolateral thigh free flap: a case report and literature review","volume":"42","author":"Nunez-Villaveiran","year":"2022","unstructured":"Nunez-Villaveiran TZamora PMasia J & Fern\u00e1ndez-Garrido M. Ankle joint salvage surgery with an ipsilateral mid-fibula osteocutaneous free flap and contralateral anterolateral thigh free flap: a case report and literature review. Microsurgery202242490\u2013499. (https:\/\/doi.org\/10.1002\/micr.30864)"},{"key":"bib11","series-title":"Journal of Bone Oncology","first-page":"15","article-title":"A comparative study between limb-salvage and amputation for treating osteosarcoma","volume":"5","author":"Li","year":"2016","unstructured":"Li XZhang YWan SLi HLi DXia JYuan ZRen MYu SLi S, et al.A comparative study between limb-salvage and amputation for treating osteosarcoma. Journal of Bone Oncology2016515\u201321. (https:\/\/doi.org\/10.1016\/j.jbo.2016.01.001)"},{"key":"bib12","series-title":"Clinical Orthopaedics and Related Research","first-page":"1262","article-title":"Lateral ankle stabilization after distal fibular resection using a novel approach: a surgical technique","volume":"472","author":"Monson","year":"2014","unstructured":"Monson DKVojdani SDean TJ & Louis-Ugbo J. Lateral ankle stabilization after distal fibular resection using a novel approach: a surgical technique. Clinical Orthopaedics and Related Research20144721262\u20131270. (https:\/\/doi.org\/10.1007\/s11999-013-3408-6)"},{"key":"bib13","series-title":"Journal of Orthopaedic Case Reports","first-page":"52","article-title":"Giant cell tumour of distal fibula managed by en block resection and reconstruction with ipsilateral proximal fibula","volume":"5","author":"Nadkarni","year":"2015","unstructured":"Nadkarni SPunit AS & Nair RV. Giant cell tumour of distal fibula managed by en block resection and reconstruction with ipsilateral proximal fibula. Journal of Orthopaedic Case Reports2015552\u201354. (https:\/\/doi.org\/10.13107\/jocr.2250-0685.255)"},{"key":"bib14","series-title":"Journal of Clinical Medicine","first-page":"3038","article-title":"Malignant bone and soft tissue lesions of the foot","volume":"12","author":"Angelini","year":"2023","unstructured":"Angelini ABiz CCerchiaro MLonghi V & Ruggieri P. Malignant bone and soft tissue lesions of the foot. Journal of Clinical Medicine2023123038. 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Archives of Orthopaedic and Trauma Surgery2005125713\u2013720. (https:\/\/doi.org\/10.1007\/s00402-005-0054-9)"},{"key":"bib17","series-title":"Journal of Clinical Orthopaedics and Trauma","first-page":"467","article-title":"Is minimal reconstruction (meshplasty) adequate to restore ankle function after excision of distal fibula tumors?","volume":"11","author":"Prajapati","year":"2020","unstructured":"Prajapati AGulia AHegde P & Puri A. Is minimal reconstruction (meshplasty) adequate to restore ankle function after excision of distal fibula tumors?Journal of Clinical Orthopaedics and Trauma202011467\u2013470. (https:\/\/doi.org\/10.1016\/j.jcot.2020.03.023)"},{"key":"bib18","series-title":"Current Oncology","first-page":"3463","article-title":"Distal fibula reconstruction in primary malignant tumours","volume":"28","author":"Khal","year":"2021","unstructured":"Khal AAZucchini RGiannini CSambri ADonati DM & De Paolis M. Distal fibula reconstruction in primary malignant tumours. Current Oncology2021283463\u20133473. (https:\/\/doi.org\/10.3390\/curroncol28050299)"},{"key":"bib19","series-title":"Orthopedic Reviews","first-page":"7236","article-title":"Primary leiomyosarcoma of the distal fibula: a case report and review of the literature","volume":"9","author":"Hanafy","year":"2017","unstructured":"Hanafy MSchwonzen MKuhnen CSchley B & Wilke A. Primary leiomyosarcoma of the distal fibula: a case report and review of the literature. Orthopedic Reviews201797236. (https:\/\/doi.org\/10.4081\/or.2017.7236)"},{"key":"bib20","series-title":"Journal of Bone and Joint Surgery","first-page":"138","article-title":"Treatment of a severe neglected valgus deformity after excision of the distal fibula for Ewing\u2019s sarcoma","volume":"94","author":"Jung","year":"2012","unstructured":"Jung STPark HW & Chung JY. Treatment of a severe neglected valgus deformity after excision of the distal fibula for Ewing\u2019s sarcoma. Journal of Bone and Joint Surgery201294138\u2013140. (https:\/\/doi.org\/10.1302\/0301-620X.94B1.27784)"},{"key":"bib21","series-title":"Clinical Orthopaedics and Related Research","first-page":"199","article-title":"Survivorship analysis in patients with periosteal chondrosarcoma","volume":"448","author":"Papagelopoulos","year":"2006","unstructured":"Papagelopoulos PJGalanis ECMavrogenis AFSavvidou ODBond JRUnni KK & Sim FH. Survivorship analysis in patients with periosteal chondrosarcoma. Clinical Orthopaedics and Related Research2006448199\u2013207. (https:\/\/doi.org\/10.1097\/01.blo.0000194684.40624.a8)"},{"key":"bib22","series-title":"Clinical Orthopaedics and Related Research","first-page":"209","article-title":"Lateral malleolus en bloc resection and ankle reconstruction for malignant tumors","volume":"437","author":"Papagelopoulos","year":"2005","unstructured":"Papagelopoulos PJSavvidou ODMavrogenis AFGalanis ECShaughnessy WJUnni KK & Sim FH. Lateral malleolus en bloc resection and ankle reconstruction for malignant tumors. Clinical Orthopaedics and Related Research2005437209\u2013218. (https:\/\/doi.org\/10.1097\/01.blo.0000164356.99795.a2)"},{"key":"bib23","series-title":"Journal of Pediatric Orthopedics","first-page":"55","article-title":"Valgus deformity after fibular resection in children","volume":"23","author":"Gonz\u00e1lez-Herranz","year":"2003","unstructured":"Gonz\u00e1lez-Herranz Pdel R\u00edo ABurgos JL\u00f3pez-Mondejar JA & Rapariz JM. Valgus deformity after fibular resection in children. Journal of Pediatric Orthopedics20032355\u201359. (https:\/\/doi.org\/10.1097\/01241398-200301000-00011)"},{"key":"bib24","series-title":"Foot and Ankle International","first-page":"746","article-title":"Adamantinoma arising in the distal fibula treated with distal fibulectomy: a case report and review of the literature","volume":"18","author":"Mohler","year":"1997","unstructured":"Mohler DG & Cunningham DC. Adamantinoma arising in the distal fibula treated with distal fibulectomy: a case report and review of the literature. Foot and Ankle International199718746\u2013751. (https:\/\/doi.org\/10.1177\/107110079701801112)"},{"key":"bib25","series-title":"Archives of Orthopaedic and Trauma Surgery","first-page":"475","article-title":"Surgical treatment of bone sarcomas of the fibula. Analysis of 19 cases","volume":"116","author":"Ozaki","year":"1997","unstructured":"Ozaki THillmann ALindner N & Winkelmann W. Surgical treatment of bone sarcomas of the fibula. Analysis of 19 cases. Archives of Orthopaedic and Trauma Surgery1997116475\u2013479. (https:\/\/doi.org\/10.1007\/BF00387580)"},{"key":"bib26","series-title":"Acta Orthopaedica Belgica","first-page":"87","article-title":"En-bloc resection of the distal fibula for aneurysmal bone cyst","volume":"59","author":"Caso Mart\u00ednez","year":"1993","unstructured":"Caso Mart\u00ednez JGonzalez Acha JGonzalez Galarraga JI & Sarobe Andueza JM. En-bloc resection of the distal fibula for aneurysmal bone cyst. Acta Orthopaedica Belgica19935987\u201389."},{"key":"bib27","series-title":"Cancer","first-page":"3514","article-title":"Nonepiphyseal giant cell tumor of the long bones. Clinical, radiologic, and pathologic study","volume":"71","author":"Fain","year":"1993","unstructured":"Fain JSUnni KKBeabout JW & Rock MG. Nonepiphyseal giant cell tumor of the long bones. Clinical, radiologic, and pathologic study. Cancer1993713514\u20133519. (https:\/\/doi.org\/10.1002\/1097-0142(19930601)71:11<3514::aid-cncr2820711109>3.0.co;2-a)"},{"key":"bib28","series-title":"Bulletin of the Hospital for Joint Diseases Orthopaedic Institute","first-page":"183","article-title":"Malignant fibrous histiocytoma of the distal fibula: a case report","volume":"50","author":"Uhl","year":"1990","unstructured":"Uhl RLSegalman KAFetto J & Present D. Malignant fibrous histiocytoma of the distal fibula: a case report. Bulletin of the Hospital for Joint Diseases Orthopaedic Institute199050183\u2013188."},{"key":"bib29","series-title":"Journal of Bone and Joint Surgery. American Volume","first-page":"1472","article-title":"Subperiosteal resection of the distal portion of the fibula for aneurysmal bone cyst. Report of two cases","volume":"52","author":"Shoji","year":"1970","unstructured":"Shoji HKoshino TMarcove RC & Thompson TC. Subperiosteal resection of the distal portion of the fibula for aneurysmal bone cyst. Report of two cases. Journal of Bone and Joint Surgery. American Volume1970521472\u20131476. (https:\/\/doi.org\/10.2106\/00004623-197052070-00026)"},{"key":"bib30","series-title":"International Journal of Surgery Case Reports","first-page":"105611","article-title":"Distal fibular excision: a review of the literature and presentation of our reconstruction technique case series","volume":"80","author":"Lamb","year":"2021","unstructured":"Lamb AMueller JLevy EHobbs JL & Brien E. Distal fibular excision: a review of the literature and presentation of our reconstruction technique case series. International Journal of Surgery Case Reports202180105611. (https:\/\/doi.org\/10.1016\/j.ijscr.2021.01.105)"},{"key":"bib31","series-title":"International Orthopaedics","first-page":"87","article-title":"Reconstruction after wide resection of the entire distal fibula in malignant bone tumours","volume":"35","author":"Dieckmann","year":"2011","unstructured":"Dieckmann RAhrens HStreitb\u00fcrger ABudny TBHenrichs MPVieth VGebert C & Hardes J. Reconstruction after wide resection of the entire distal fibula in malignant bone tumours. International Orthopaedics20113587\u201392. (https:\/\/doi.org\/10.1007\/s00264-009-0931-x)"},{"key":"bib32","series-title":"Journal of Foot and Ankle Surgery","first-page":"353","article-title":"Lateral ankle reconstruction using a patellar tendon graft: a case report","volume":"48","author":"Schuurman","year":"2009","unstructured":"Schuurman W & Willems WJ. Lateral ankle reconstruction using a patellar tendon graft: a case report. Journal of Foot and Ankle Surgery200948353\u2013357. (https:\/\/doi.org\/10.1053\/j.jfas.2009.02.002)"},{"issue":"415","key":"bib33","series-title":"Clinical Orthopaedics and Related Research","first-page":"232","article-title":"Salvage reconstruction for lateral ankle instability using a tendon allograft","author":"Su","year":"2003","unstructured":"Su EP & Healey JH. Salvage reconstruction for lateral ankle instability using a tendon allograft. Clinical Orthopaedics and Related Research2003 (415) 232\u2013238. (https:\/\/doi.org\/10.1097\/01.blo.0000092976.12414.b0)"},{"key":"bib34","series-title":"Journal of International Medical Research","first-page":"381","article-title":"Distal fibula resection in osteochondroma","volume":"24","author":"Durak","year":"1996","unstructured":"Durak KBilgen OKaleli T & Aydinli U. Distal fibula resection in osteochondroma. Journal of International Medical Research199624381\u2013386. (https:\/\/doi.org\/10.1177\/030006059602400411)"},{"key":"bib35","series-title":"Acta Orthopaedica Scandinavica","first-page":"290","article-title":"Reconstruction after resection of the distal fibula for bone tumor","volume":"57","author":"Capanna","year":"1986","unstructured":"Capanna Rvan Horn JRBiagini RRuggieri PBettelli G & Campanacci M. Reconstruction after resection of the distal fibula for bone tumor. Acta Orthopaedica Scandinavica198657290\u2013294. (https:\/\/doi.org\/10.3109\/17453678608994394)"},{"key":"bib36","series-title":"Clinical Orthopaedics and Related Research","first-page":"105","article-title":"Ankle stability after resection of the distal third of the fibula for giant-cell lesions: report of two cases","volume":"155","author":"Yadav","year":"1981","unstructured":"Yadav SS. Ankle stability after resection of the distal third of the fibula for giant-cell lesions: report of two cases. Clinical Orthopaedics and Related Research1981155105\u2013107. (https:\/\/doi.org\/10.1097\/00003086-198103000-00019)"},{"key":"bib37","series-title":"Journal of Orthopaedic Case Reports","first-page":"19","article-title":"Limb salvage surgery in fungating giant cell tumors: a report of three cases","volume":"11","author":"Rangaswamy","year":"2021","unstructured":"Rangaswamy NKumar VSBanjara RMajeed AGoyal D & Khan SA. Limb salvage surgery in fungating giant cell tumors: a report of three cases. Journal of Orthopaedic Case Reports20211119\u201323. (https:\/\/doi.org\/10.13107\/jocr.2021.v11.i02.2008)"},{"key":"bib38","series-title":"Journal of Surgical Oncology","first-page":"375","article-title":"Clinically significant thromboembolic disease in orthopedic oncology: an analysis of 986 patients treated with low-molecular-weight heparin","volume":"102","author":"Ruggieri","year":"2010","unstructured":"Ruggieri PMontalti MPala EAngelini ACalabr\u00f2 TErrani C & Mercuri M. Clinically significant thromboembolic disease in orthopedic oncology: an analysis of 986 patients treated with low-molecular-weight heparin. Journal of Surgical Oncology2010102375\u2013379. (https:\/\/doi.org\/10.1002\/jso.21645)"},{"key":"bib39","series-title":"Journal of Personalized Medicine","first-page":"278","article-title":"One-stage soft tissue reconstruction following sarcoma excision: a personalized multidisciplinary approach called \u201corthoplasty\u201d","volume":"10","author":"Angelini","year":"2020","unstructured":"Angelini ATiengo CSonda RBerizzi ABassetto F & Ruggieri P. One-stage soft tissue reconstruction following sarcoma excision: a personalized multidisciplinary approach called \u201corthoplasty\u201d. Journal of Personalized Medicine202010278. (https:\/\/doi.org\/10.3390\/jpm10040278)"},{"key":"bib40","series-title":"Orthopaedic Surgery","first-page":"782","article-title":"Lateral malleolus reconstruction after tumor resection in children: a case report and literature review","volume":"14","author":"Long","year":"2022","unstructured":"Long ZYLu YChen GLi MHuang MXiao XWang Z & Li J. Lateral malleolus reconstruction after tumor resection in children: a case report and literature review. Orthopaedic Surgery202214782\u2013786. (https:\/\/doi.org\/10.1111\/os.13205)"},{"key":"bib41","series-title":"Journal of Orthopaedic Case Reports","first-page":"92","article-title":"Management of lateral malleolus giant cell tumor using A reverse proximal fibular graft-A case report","volume":"11","author":"Karmakar","year":"2021","unstructured":"Karmakar AMondal KChatterjee ARay U & Chakraborty S. Management of lateral malleolus giant cell tumor using A reverse proximal fibular graft-A case report. Journal of Orthopaedic Case Reports20211192\u201395. 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Journal of Clinical Orthopaedics and Trauma2019101054\u20131058. (https:\/\/doi.org\/10.1016\/j.jcot.2019.03.010) Erratum in: Journal of Clinical Orthopaedics and Trauma. 202111101570."},{"key":"bib44","series-title":"Foot and Ankle Surgery","first-page":"855","article-title":"Lateral malleolus en bloc resection for the distal fibula osteosarcoma based on a new classification and proposed reconstruction choice: analysis of 6 cases prognosis and literature review","volume":"26","author":"Wang","year":"2020","unstructured":"Wang JDu ZYang RTang X & Guo W. Lateral malleolus en bloc resection for the distal fibula osteosarcoma based on a new classification and proposed reconstruction choice: analysis of 6 cases prognosis and literature review. Foot and Ankle Surgery202026855\u2013863. (https:\/\/doi.org\/10.1016\/j.fas.2019.11.003)"},{"key":"bib45","series-title":"Cureus","first-page":"e666","article-title":"A rare giant cell tumor of the distal fibula and its management","volume":"8","author":"Vaishya","year":"2016","unstructured":"Vaishya RKapoor CGolwala PAgarwal AK & Vijay V. A rare giant cell tumor of the distal fibula and its management. Cureus20168e666. (https:\/\/doi.org\/10.7759\/cureus.666)"},{"key":"bib46","series-title":"Journal of Foot and Ankle Surgery","first-page":"397","article-title":"Reverse transfer of the proximal vascularized fibula to reconstruct the lateral malleolus: a case report and literature review","volume":"55","author":"Gao","year":"2016","unstructured":"Gao YSZhang CQ & Sheng JG. Reverse transfer of the proximal vascularized fibula to reconstruct the lateral malleolus: a case report and literature review. Journal of Foot and Ankle Surgery201655397\u2013400. (https:\/\/doi.org\/10.1053\/j.jfas.2015.02.004)"},{"key":"bib47","series-title":"Revista Brasileira de Ortopedia","first-page":"563","article-title":"Chondromyxoid fibroma of the distal fibula in a pediatric patient: a case report","volume":"48","author":"Tomazini","year":"2013","unstructured":"Tomazini ACCCarniel JP & da Cunha LAM. Chondromyxoid fibroma of the distal fibula in a pediatric patient: a case report. Revista Brasileira de Ortopedia201348563\u2013566. (https:\/\/doi.org\/10.1016\/j.rboe.2013.12.005)"},{"key":"bib48","series-title":"Foot and Ankle Surgery","first-page":"31","article-title":"Reconstruction of distal fibula with osteoarticular allograft after tumor resection","volume":"19","author":"Jamshidi","year":"2013","unstructured":"Jamshidi KMazhar FN & Masdari Z. Reconstruction of distal fibula with osteoarticular allograft after tumor resection. Foot and Ankle Surgery20131931\u201335. (https:\/\/doi.org\/10.1016\/j.fas.2012.09.001)"},{"key":"bib49","series-title":"Journal of Bone and Joint Surgery","first-page":"1356","article-title":"Aneurysmal bone cysts of the distal fibula in children: long-term results of curettage and resection in nine patients","volume":"89","author":"Lampasi","year":"2007","unstructured":"Lampasi MMagnani M & Donzelli O. Aneurysmal bone cysts of the distal fibula in children: long-term results of curettage and resection in nine patients. Journal of Bone and Joint Surgery2007891356\u20131362. (https:\/\/doi.org\/10.1302\/0301-620X.89B10.19375)"},{"key":"bib50","series-title":"Journal of Bone and Joint Surgery","first-page":"396","article-title":"Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome","volume":"88","author":"Leichtle","year":"2006","unstructured":"Leichtle CILeichtle UGG\u00e4rtner VSchimmel HHartmann JT & Rudert M. Multiple skeletal metastases from a giant cell tumour of the distal fibula with fatal outcome. Journal of Bone and Joint Surgery200688396\u2013399. (https:\/\/doi.org\/10.1302\/0301-620X.88B3.16606)"},{"key":"bib51","series-title":"Skeletal Radiology","first-page":"750","article-title":"Hemangioendothelioma with an epithelioid phenotype arising in hemangioma of the fibula","volume":"34","author":"Shah","year":"2005","unstructured":"Shah ZKPeh WCGShek TWHWong JWK & Chien EP. Hemangioendothelioma with an epithelioid phenotype arising in hemangioma of the fibula. Skeletal Radiology200534750\u2013754. (https:\/\/doi.org\/10.1007\/s00256-005-0912-0)"},{"key":"bib52","series-title":"Journal of Reconstructive Microsurgery","first-page":"371","article-title":"Reconstruction of the form and function of lateral malleolus and ankle joint","volume":"21","author":"Kiyokawa","year":"2005","unstructured":"Kiyokawa KTanaka SKiduka YInoue YYamauchi T & Tai Y. Reconstruction of the form and function of lateral malleolus and ankle joint. Journal of Reconstructive Microsurgery200521371\u2013376. (https:\/\/doi.org\/10.1055\/s-2005-915204)"},{"key":"bib53","series-title":"Journal of Bone and Joint Surgery","first-page":"878","article-title":"Lateral malleolar reconstruction after distal fibular resection: a case report","volume":"87","author":"Leibner","year":"2005","unstructured":"Leibner EDAd-El DLiebergall MOfiram ELondon E & Peyser A. Lateral malleolar reconstruction after distal fibular resection: a case report. Journal of Bone and Joint Surgery200587878\u2013882. (https:\/\/doi.org\/10.2106\/JBJS.D.02539)"},{"key":"bib54","series-title":"Archives of Orthopaedic and Trauma Surgery","first-page":"56","article-title":"Giant cell tumor of the distal fibula: fifteen-year result after en bloc resection and fibula reconstruction","volume":"124","author":"Eger","year":"2004","unstructured":"Eger WSch\u00f6rle C & Zeiler G. Giant cell tumor of the distal fibula: fifteen-year result after en bloc resection and fibula reconstruction. Archives of Orthopaedic and Trauma Surgery200412456\u201359. (https:\/\/doi.org\/10.1007\/s00402-003-0562-4)"},{"key":"bib55","series-title":"Journal of Pediatric Orthopedics. Part B","first-page":"176","article-title":"Distal fibular reconstruction with pedicled vascularized fibular head graft: a case report","volume":"11","author":"de Gauzy","year":"2002","unstructured":"de Gauzy JSKany J & Cahuzac JP. Distal fibular reconstruction with pedicled vascularized fibular head graft: a case report. Journal of Pediatric Orthopedics. Part B200211176\u2013180. (https:\/\/doi.org\/10.1097\/00009957-200204000-00017)"},{"key":"bib56","series-title":"Journal of Postgraduate Medicine","first-page":"83","article-title":"Distal fibular giant cell tumour","volume":"41","author":"Dogra","year":"1995","unstructured":"Dogra ASKulkarni SS & Bhosale PB. Distal fibular giant cell tumour. Journal of Postgraduate Medicine19954183\u201384."},{"key":"bib57","series-title":"Archives of Orthopaedic and Traumatic Surgery","first-page":"71","article-title":"Excisional biopsy for bone tumours","volume":"94","author":"Persson","year":"1979","unstructured":"Persson BM & Rydholm A. Excisional biopsy for bone tumours. Archives of Orthopaedic and Traumatic Surgery19799471\u201374. (https:\/\/doi.org\/10.1007\/BF00448097)"},{"key":"bib58","series-title":"Journal of Bone and Joint Surgery","first-page":"627","article-title":"Transplantation of the fibula in the same leg","volume":"20","author":"Carrel","year":"1938","unstructured":"Carrel WB. Transplantation of the fibula in the same leg. Journal of Bone and Joint Surgery193820627\u2013634."},{"key":"bib59","series-title":"European Journal of Orthopaedic Surgery & Traumatology","first-page":"737","article-title":"Intercalary reconstructions after bone tumor resections: a review of treatments","volume":"27","author":"Panagopoulos","year":"2017","unstructured":"Panagopoulos GNMavrogenis AFMauffrey CLesensk\u00fd JAngelini AMegaloikonomos PDIgoumenou VGPapanastassiou JSavvidou ORuggieri P, et al.Intercalary reconstructions after bone tumor resections: a review of treatments. European Journal of Orthopaedic Surgery & Traumatology201727737\u2013746. (https:\/\/doi.org\/10.1007\/s00590-017-1985-x)"},{"key":"bib60","series-title":"Archives of Bone and Joint Surgery","first-page":"548","article-title":"An epidemiological study of primary bone tumors of the fibula","volume":"9","author":"G\u00fcm\u00fc\u015fta\u015f","year":"2021","unstructured":"G\u00fcm\u00fc\u015fta\u015f SA\u00c7evik HB & Kayahan S. An epidemiological study of primary bone tumors of the fibula. Archives of Bone and Joint Surgery20219548\u2013553. (https:\/\/doi.org\/10.22038\/abjs.2020.47057.2299)"},{"key":"bib61","series-title":"International Orthopaedics","first-page":"1907","article-title":"Clinical management and surgical treatment of distal fibular tumours: a case series and review of the literature","volume":"36","author":"Perisano","year":"2012","unstructured":"Perisano CMarzetti ESpinelli MSGraci CFabbriciani CMaffulli N & Maccauro G. Clinical management and surgical treatment of distal fibular tumours: a case series and review of the literature. International Orthopaedics2012361907\u20131913. (https:\/\/doi.org\/10.1007\/s00264-012-1536-3)"},{"key":"bib62","series-title":"Foot and Ankle International","first-page":"135","article-title":"Ipsilateral fibular slide grafts in the management of distal fibula lesions","volume":"20","author":"Rizzo","year":"1999","unstructured":"Rizzo MScully SP & Harrelson JM. Ipsilateral fibular slide grafts in the management of distal fibula lesions. Foot and Ankle International199920135\u2013136. (https:\/\/doi.org\/10.1177\/107110079902000212)"},{"key":"bib63","series-title":"Journal of Foot and Ankle Surgery","first-page":"564","article-title":"Mitigating risk of ankle valgus from ankle osteochondroma resection using a transfibular approach: a retrospective study with six years of follow-up","volume":"56","author":"Appy-Fedida","year":"2017","unstructured":"Appy-Fedida BKrief EDeroussen FPlancq MCCollet LMKlein C & Gouron R. Mitigating risk of ankle valgus from ankle osteochondroma resection using a transfibular approach: a retrospective study with six years of follow-up. Journal of Foot and Ankle Surgery201756564\u2013567. (https:\/\/doi.org\/10.1053\/j.jfas.2017.01.029)"},{"key":"bib64","series-title":"JBJS Case Connector","first-page":"e20.00046","article-title":"Total tibial allograft reconstruction for adamantinoma: a case report with 2-year follow-up","volume":"10","author":"Callan","year":"2020","unstructured":"Callan AKSingleterry SCzerniak BASelber JC & Satcher RL. Total tibial allograft reconstruction for adamantinoma: a case report with 2-year follow-up. JBJS Case Connector202010e20.00046. (https:\/\/doi.org\/10.2106\/JBJS.CC.20.00046)"},{"key":"bib65","series-title":"Rare Tumors","first-page":"6823","article-title":"Adamantinoma arising in the distal end of the fibula","volume":"9","author":"Yoshida","year":"2017","unstructured":"Yoshida SMurakami TSuzuki KItou SWatanuki MHosaka M & Hagiwara Y. Adamantinoma arising in the distal end of the fibula. Rare Tumors201796823. (https:\/\/doi.org\/10.4081\/rt.2017.6823)"},{"key":"bib66","series-title":"Journal of Pediatric Orthopedics","first-page":"e67","article-title":"Preliminary results of the induced membrane technique for the reconstruction of large bone defects","volume":"37","author":"Mansour","year":"2017","unstructured":"Mansour TM & Ghanem IB. Preliminary results of the induced membrane technique for the reconstruction of large bone defects. Journal of Pediatric Orthopedics201737e67\u2013e74. (https:\/\/doi.org\/10.1097\/BPO.0000000000000663)"},{"key":"bib67","series-title":"Journal of Orthopaedic Surgery","first-page":"122","article-title":"Multifocal epithelioid hemangioendothelioma of the foot and ankle: a case report","volume":"22","author":"Bisbinas","year":"2014","unstructured":"Bisbinas IKarabouta ZGeorgiannos DLampridis V & Badekas A. Multifocal epithelioid hemangioendothelioma of the foot and ankle: a case report. Journal of Orthopaedic Surgery201422122\u2013125. (https:\/\/doi.org\/10.1177\/230949901402200130)"},{"key":"bib68","series-title":"Orthopaedics & Traumatology, Surgery & Research","first-page":"301","article-title":"Induced membrane technique for reconstruction after bone tumor resection in children: a preliminary study","volume":"98","author":"Chotel","year":"2012","unstructured":"Chotel FNguiabanda LBraillon PKohler RB\u00e9rard J & Abelin-Genevois K. Induced membrane technique for reconstruction after bone tumor resection in children: a preliminary study. Orthopaedics & Traumatology, Surgery & Research201298301\u2013308. (https:\/\/doi.org\/10.1016\/j.otsr.2011.11.008)"},{"key":"bib69","series-title":"Journal of Bone and Joint Surgery","first-page":"803","article-title":"Prosthetic reconstruction for tumours of the distal tibia and fibula","volume":"81","author":"Lee","year":"1999","unstructured":"Lee SHKim HSPark YBRhie TY & Lee HK. Prosthetic reconstruction for tumours of the distal tibia and fibula. Journal of Bone and Joint Surgery199981803\u2013807. (https:\/\/doi.org\/10.1302\/0301-620x.81b5.9588)"},{"key":"bib70","series-title":"Journal of Bone and Joint Surgery","first-page":"1227","article-title":"Subperiosteal resection of aneurysmal bone cysts of the distal fibula","volume":"91","author":"Abuhassan","year":"2009","unstructured":"Abuhassan FO & Shannak AO. Subperiosteal resection of aneurysmal bone cysts of the distal fibula. Journal of Bone and Joint Surgery2009911227\u20131231. 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