{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:18:49Z","timestamp":1784557129822,"version":"3.55.0"},"reference-count":48,"publisher":"Bioscientifica","issue":"9","content-domain":{"domain":["erc.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>\n                    The vagus nerve (cranial nerve X) is the main nerve of the parasympathetic division of the autonomic nervous system. Vagal paragangliomas (VPGLs) are a prime example of an endocrine tumor associated with the vagus nerve. This rare, neural crest tumor constitutes the second most common site of hereditary head and neck paragangliomas (HNPGLs), most often in relation to mutations in the succinate dehydrogenase complex subunit D (\n                    <jats:italic>SDHD<\/jats:italic>\n                    ) gene. The treatment paradigm for VPGL has progressively shifted from surgery to abstention or therapeutic radiation with curative-like outcomes. Parathyroid tissue and parathyroid adenoma can also be found in close association with the vagus nerve in intra or paravagal situations. Vagal parathyroid adenoma can be identified with preoperative imaging or suspected intraoperatively by experienced surgeons. Vagal parathyroid adenomas located in the neck or superior mediastinum can be removed via initial cervicotomy, while those located in the aortopulmonary window require a thoracic approach. This review particularly emphasizes the embryology, molecular genetics, and modern imaging of these tumors.\n                  <\/jats:p>","DOI":"10.1530\/erc-16-0241","type":"journal-article","created":{"date-parts":[[2016,7,12]],"date-time":"2016-07-12T22:23:08Z","timestamp":1468362188000},"page":"R371-R379","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":12,"title":["Endocrine tumors associated with the vagus nerve"],"prefix":"10.1530","volume":"23","author":[{"given":"Arthur","family":"Varoquaux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Electron","family":"Kebebew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9deric","family":"Sebag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel","family":"Pacak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ta\u00efeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"2016081120091660000_23.9.R371.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)06176-4"},{"key":"2016081120091660000_23.9.R371.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-015-3268-2"},{"key":"2016081120091660000_23.9.R371.3","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-010-0622-1"},{"key":"2016081120091660000_23.9.R371.4","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-002-1717-3"},{"key":"2016081120091660000_23.9.R371.5","doi-asserted-by":"crossref","unstructured":"Baker CVH 2005 The embryology of vagal sensory neurons. 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