{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T14:19:33Z","timestamp":1784557173478,"version":"3.55.0"},"reference-count":6,"publisher":"Bioscientifica","issue":"8","content-domain":{"domain":["erc.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>\n                    Landmark scientific findings are applauded. However, at the time of discovery, the future impact that these types of new knowledge might have on patients is not foreseen. This article discusses how unraveling the structure of DNA has advanced medical treatment, particularly for patients with rare diseases. In addition, each new scientific discovery brings with it the emotion of\n                    <jats:bold>hope<\/jats:bold>\n                    for improved diagnosis and treatment, as well as enhanced outcomes and increased longevity for patients facing a life-long disease.\n                  <\/jats:p>","DOI":"10.1530\/erc-18-0156","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T10:50:16Z","timestamp":1530874216000},"page":"E9-E11","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-1","source":"Crossref","is-referenced-by-count":3,"title":["65 YEARS OF THE DOUBLE HELIX: Could Watson and Crick have envisioned the true impact of their discovery?"],"prefix":"10.1530","volume":"25","author":[{"given":"Ilene","family":"Sussman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"ref51","first-page":"1317","article-title":"Identification of the von Hippel-Lindau disease tumor suppressor gene.","year":"1993","journal-title":"Science"},{"key":"ref21","first-page":"1317","article-title":"Identification of the von Hippel-Lindau disease tumor suppressor gene.","year":"1993","journal-title":"Science"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/pon.1951","article-title":"Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes.","volume":"20","year":"2011","journal-title":"Psycho-oncology"},{"key":"ref01","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1399-0004.2010.01333.x","article-title":"Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.","volume":"77","year":"2010","journal-title":"Clinical Genetic"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1399-0004.2010.01333.x","article-title":"Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.","volume":"77","year":"2010","journal-title":"Clinical Genetic"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/pon.1951","article-title":"Distress in partners of individuals diagnosed with or at high risk of developing tumors due to rare hereditary cancer syndromes.","volume":"20","year":"2011","journal-title":"Psycho-oncology"}],"container-title":["Endocrine-Related Cancer"],"original-title":[],"link":[{"URL":"https:\/\/erc.bioscientifica.com\/view\/journals\/erc\/25\/8\/ERC-18-0156.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1530\/ERC-18-0156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:54:56Z","timestamp":1784555696000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.bioscientifica.com\/erc\/article\/25\/8\/E9-E11\/25200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":6,"journal-issue":{"issue":"8"},"URL":"https:\/\/doi.org\/10.1530\/erc-18-0156","relation":{},"ISSN":["1351-0088","1479-6821"],"issn-type":[{"value":"1351-0088","type":"print"},{"value":"1479-6821","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8]]}}}