{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:53:03Z","timestamp":1792144383100,"version":"4.4.0"},"reference-count":25,"publisher":"Bioscientifica","issue":"4","license":[{"start":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["etj.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,4,28]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this multicentre study was to investigate the progression of patient-reported outcomes after thyroid surgery, with emphasis on voice and swallowing difficulties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An online platform was used to collect replies to standardised questionnaires (voice handicap index, VHI; voice-related quality of life, VrQoL; EAT-10) preoperatively and at 2\u20136 weeks and 3\u20136\u201312 months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 236 patients were recruited from five centres that contributed with median of 11 cases (range 2\u2013186 cases). Average symptoms scores showed voice changes lasting up to 3 months: VHI increased from 41 \u00b1 15 (preop) to 48 \u00b1 21 (6 weeks) and returned to 41 \u00b1 15 at 6 months. Similarly, VrQoL increased from 12 \u00b1 4 to 15 \u00b1 6 and returned to 12 \u00b1 4 (6 months). Severe voice changes (VHI &gt; 60) were reported in 12% of patients preop, 22% at 2 weeks, 18% at 6 weeks, 13% at 3 months and 7% at 12 months. Only five patients with normal preoperative voice had persistent severe voice changes after 6\u201312 months. Those with severe voice changes at 2 weeks (median VHI 70.5, IQR 65\u201381) had significant improvement by 6 months (median VHI 54, IQR 39\u201365) (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                    <jats:p>Swallowing assessment showed a median preop score of 0 (IQR 0\u20133) increasing to a median of 2 (IQR 0\u20138) at 2 weeks and normal values afterwards.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:italic>ThyVoice<\/jats:italic>\n                      online platform allows the assessment of patient-reported outcome measures in thyroid surgery. Voice morbidity appears to be more frequent than commonly reported, and this risk should the quoted during informed consent. Swallowing difficulties are mild but significant in the first 2 weeks.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/etj-23-0008","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T09:47:20Z","timestamp":1682675240000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-16","source":"Crossref","is-referenced-by-count":10,"title":["Voice and swallowing symptoms after thyroid surgery assessed using the ThyVoice online platform"],"prefix":"10.1530","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6153-1970","authenticated-orcid":true,"given":"Radu","family":"Mihai","sequence":"first","affiliation":[{"name":"Department of Endocrine Surgery, Churchill Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","reference":[{"key":"bib1","series-title":"Sixth National Audit Report of the United Kingdom Registry of Endocrine and Thyroid Surgery","author":"Aspinal","year":"2021","unstructured":"Aspinal S & Mihai RSixth National Audit Report of the United Kingdom Registry of Endocrine and Thyroid Surgery2021. 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