{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:14:18Z","timestamp":1783448058424,"version":"3.55.0"},"reference-count":22,"publisher":"Bioscientifica","issue":"2","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":333,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Management of benign nodular thyroid disease (BNTD) has changed dramatically over the past two decades, as reflected by international guideline recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>We sought to document the preferences regarding the management of euthyroid BNTD among thyroid-dedicated members of the Spanish Society of Endocrinology and Nutrition (SEEN) and assess the extent to which present international guideline recommendations have been incorporated into ordinary practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An online survey on the management of a standard case of BNTD among SEEN thyroid experts and exploration of variations in management following different clinical scenarios, in which variables such as sex, age, ultrasound characteristics, fine needle aspiration results or patient preferences change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Two hundred and eleven (9% SEEN members) participated in the survey. Most of them, 147 (69.7%), recommended periodic monitoring, 43 (20.3%) surgery and 21 (10.0%) minimally invasive procedures (MIP). No participant opted for levothyroxine or radioiodine. Management of BNTD was modified based on patient preferences, both in favour of more aggressive (surgery) and more conservative (MIP or monitoring) options.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The vast majority of Spanish thyroidologists followed the international guideline recommendations for BNTD management. The trend shows the positive impact of the guideline recommendations with a shift towards more conservative management, taking into account patient preference as a binding element in therapeutic decision-making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/etj-24-0313","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T11:38:50Z","timestamp":1742557130000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-17","source":"Crossref","is-referenced-by-count":0,"title":["Management of benign nodular thyroid disease: a nationwide survey of endocrine specialists in Spain"],"prefix":"10.1530","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2017-0694","authenticated-orcid":true,"given":"Juan J","family":"D\u00edez","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Hospital Universitario Puerta de Hierro Majadahonda, Instituto de Investigaci\u00f3n Sanitaria Puerta de Hierro Segovia de Arana 1 , ,","place":["Majadahonda, Spain"]},{"name":"Department of Medicine, Universidad Aut\u00f3noma de Madrid 2 , ,","place":["Madrid, Spain"]},{"name":"SEEN (Sociedad Espa\u00f1ola de Endocrinolog\u00eda y Nutrici\u00f3n) Thyroid Task-Force, Madrid, Spain 3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0227-3566","authenticated-orcid":true,"given":"Juan C","family":"Galofr\u00e9","sequence":"additional","affiliation":[{"name":"SEEN (Sociedad Espa\u00f1ola de Endocrinolog\u00eda y Nutrici\u00f3n) Thyroid Task-Force, Madrid, Spain 3"},{"name":"Department of Endocrinology, Cl\u00ednica Universidad de Navarra 4 , ,","place":["Pamplona, Spain"]},{"name":"IdiSNA (Instituto de investigaci\u00f3n en la Salud de Navarra) 5 , ,","place":["Pamplona, 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