{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:19:00Z","timestamp":1783448340445,"version":"3.55.0"},"reference-count":28,"publisher":"Bioscientifica","issue":"5","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":284,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Iodine deficiency (ID) causes a wide range of health issues, from endemic goiter to more subtle effects resulting from reduced thyroid hormone production. The recommended daily iodine intake for adolescents and adults is 150 \u03bcg, which corresponds to a median urinary iodine concentration (UIC) of 100\u2013299 \u03bcg\/L at the population level. Individuals with anorexia nervosa typically suffer from deficiencies in micronutrients and vitamins, but there is little data on iodine status. This study assessed UIC and associated factors in a cohort of patients with anorexia nervosa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a prospective monocentric exploratory observational study performed at the Centre Vaudois anorexie boulimie (abC) and the Division interdisciplinaire de sant\u00e9 des adolescents (DISA) of the Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland. The study included 39 patients with anorexia nervosa, aged \u226514 years, recruited between May and August 2022. After obtaining informed consent, anthropometric data were extracted from the electronic medical record and random spot urine samples were collected. The UIC was determined by ion-chromatography mass spectrometry.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median age (IQR) was 18 (14\u201362) years and median body mass index (BMI) was 17.72 (14.86\u201323.54) kg\/m2. Median UIC was 67.7 \u03bcg\/L, and 22\/39 individuals had a UIC &amp;lt;100 \u03bcg\/L. There was a positive correlation between BMI and UIC (P = 0.047).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings suggest that patients with anorexia nervosa are at risk of ID, and lower BMI predicts lower UIC. Although these data need to be corroborated in a larger cohort, clinicians caring for patients with anorexia should consider recommending an iodine-containing multivitamin.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1530\/etj-25-0076","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T11:41:41Z","timestamp":1756986101000},"update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-17","source":"Crossref","is-referenced-by-count":0,"title":["Nutritional iodine intake in patients with anorexia nervosa"],"prefix":"10.1530","volume":"14","author":[{"given":"Sophie","family":"Seydoux","sequence":"first","affiliation":[{"name":"1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Halbout","sequence":"additional","affiliation":[{"name":"2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Gebhard","sequence":"additional","affiliation":[{"name":"3"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B","family":"Zimmerman","sequence":"additional","affiliation":[{"name":"4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5980-0529","authenticated-orcid":true,"given":"Peter A","family":"Kopp","sequence":"additional","affiliation":[{"name":"2"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"2026070714012752500_bib1","first-page":"59","article-title":"Thyroid hormone synthesis","volume-title":"Werner and Ingbar\u2019s The Thyroid: A Fundamental and Clinical Text","author":"Kopp","year":"2020","edition":"11th edn"},{"key":"2026070714012752500_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.beem.2004.03.012","article-title":"Maternal thyroid hormones early in pregnancy and fetal brain development","volume":"18","author":"De Escobar","year":"2004","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"2026070714012752500_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0223348","article-title":"Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: a randomized trial","volume":"14","author":"Gebreegziabher","year":"2019","journal-title":"PLoS One"},{"key":"2026070714012752500_bib4","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S2213-8587(17)30332-7","article-title":"Effect of iodine supplementation in pregnant women on child neurodevelopment: a randomised, double-blind, placebo-controlled trial","volume":"5","author":"Gowachirapant","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2026070714012752500_bib5","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1365-3016.2012.01275.x","article-title":"The effects of iodine deficiency in pregnancy and infancy","volume":"26","author":"Zimmermann","year":"2012","journal-title":"Paediatr Perinat Epidemiol"},{"key":"2026070714012752500_bib6","doi-asserted-by":"crossref","first-page":"918S","DOI":"10.3945\/ajcn.115.110429","article-title":"Consequences of iodine deficiency and excess in pregnant women: an overview of current knowns and unknowns","volume":"104","author":"Pearce","year":"2016","journal-title":"Am J Clin Nutr"},{"key":"2026070714012752500_bib7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1089\/thy.2022.0454","article-title":"The prevention of iodine deficiency: a history","volume":"33","author":"Pearce","year":"2023","journal-title":"Thyroid"},{"key":"2026070714012752500_bib8","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1093\/jn\/138.11.2060","article-title":"Research on iodine deficiency and goiter in the 19th and early 20th centuries","volume":"138","author":"Zimmermann","year":"2008","journal-title":"J Nutr"},{"key":"2026070714012752500_bib9","first-page":"1","volume-title":"Assessment of Iodine Deficiency Disorders and Monitoring Their Elimination: A Guide for Programme Managers","author":"World Health Organization","year":"2007","edition":"3rd edn"},{"key":"2026070714012752500_bib10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1089\/thy.2013.0128","article-title":"Global iodine nutrition: where do we stand in 2013?","volume":"23","author":"Pearce","year":"2013","journal-title":"Thyroid"},{"key":"2026070714012752500_bib11","article-title":"[Internet]","author":"Global scorecard of iodine nutrition 2023","year":"2025"},{"key":"2026070714012752500_bib12","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.3390\/nu12061606","article-title":"Vegans, vegetarians, and omnivores: how does dietary choice influence iodine intake? 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