{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T23:46:22Z","timestamp":1767915982236,"version":"3.49.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1979,5,1]],"date-time":"1979-05-01T00:00:00Z","timestamp":294364800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["reproduction-online.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1979,5,1]]},"abstract":"<jats:p>Summary. The effect of prostaglandin (PG)-induced luteolysis on the myometrial activity in 20\u201321-day-pregnant and 11\u201312-day-pseudopregnant rabbits was studied by intrauterine pressure (IUP) recording during PG infusions. The same dose of PG (10 \u03bcg\/h during 8 h) was also given to 7 non-pregnant (untreated) does that were used as controls. Peripheral plasma concentration of progesterone and oestradiol-17\u03b2 were measured at 2-h intervals during the infusion.<\/jats:p>\n                  <jats:p>Plasma progesterone level decreased significantly within 2 h of the start of infusion in pregnant and pseudopregnant does and continued to decrease; at the end of 8 h, the concentrations were 31 and 41% respectively, of the pre-infusion levels. The amplitude of uterine contractions increased significantly after 4 h in pseudopregnant does, increased slightly but insignificantly in the pregnant does and showed no significant change in the non-pregnant does during PG infusion. The amplitudes developed in the pregnant and pseudopregnant does were significantly different.<\/jats:p>\n                  <jats:p>The direct effect of progesterone (1\u20133 \u03bcg\/h during 4 h) was also studied in 7 non-pregnant rabbits. After 2 h the amplitude of contractions had decreased markedly and the pattern of activity had become irregular.<\/jats:p>\n                  <jats:p>The results support the concept of a myometrial inhibitory factor other than progesterone in rabbit pregnancy and suggest that this factor(s) originates in the conceptus.<\/jats:p>","DOI":"10.1530\/jrf.0.0560141","type":"journal-article","created":{"date-parts":[[2004,3,20]],"date-time":"2004-03-20T03:12:46Z","timestamp":1079752366000},"page":"141-148","update-policy":"https:\/\/doi.org\/10.1530\/rep\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Prostaglandin-induced luteolysis in pregnant and pseudopregnant rabbits and the resultant effects on the myometrial activity"],"prefix":"10.1093","volume":"56","author":[{"given":"T.","family":"Lauda\u0144ski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Batra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"\u00c5kerlund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1979,5,1]]},"container-title":["Reproduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/56\/1\/141\/64934422\/jrf_56_1_022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/56\/1\/141\/64934422\/jrf_56_1_022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T18:17:19Z","timestamp":1767896239000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/56\/1\/141\/8290173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,5,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1979,5,1]]}},"URL":"https:\/\/doi.org\/10.1530\/jrf.0.0560141","relation":{},"ISSN":["1470-1626","1741-7899"],"issn-type":[{"value":"1470-1626","type":"print"},{"value":"1741-7899","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1979,5,1]]},"published":{"date-parts":[[1979,5,1]]}}}