{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T21:31:52Z","timestamp":1767821512364,"version":"3.49.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[1984,11,1]],"date-time":"1984-11-01T00:00:00Z","timestamp":468115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["reproduction-online.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1984,11,1]]},"abstract":"<jats:title>Summary.<\/jats:title>\n                  <jats:p>The present study reports steroid metabolism by corpora lutea (CL) obtained from skunks with diapausing embryos ('delay' CL) and with activated embryos (activated CL). CL from both reproductive periods were incubated with various radioactive precursors. Control incubations without any tissue or with 50 \u03bcl of packed skunk blood cells were also conducted simultaneously. Incubation of skunk CL with [3H]pregnenolone for 3 h resulted in 36% of the precursor accumulating as progesterone. Metabolism of [3H]dehydroepiandrosterone (DHEA) to androstenedione proceeded with approximately the same amount of product accumulating (34\u201346%) as was observed in the conversion of pregnenolone to progesterone. These results suggest that \u03945 isomerase, 3\u03b2-hydroxysteroid dehydrogenase, is the most prominent enzyme in skunk CL. Metabolism of [3H]pregnenolone to 17\u03b1-hydroxypregnenolone and [3H]progesterone to 17\u03b1-hydroxyprogesterone occurred at low rates (1\u20137%), suggesting the presence of C2l steroid 17\u03b1-hydroxylase in skunk CL. Aromatase activity, as estimated by measuring accumulation of oestradiol-17\u03b2 from [3H]testosterone, was demonstrated in activated CL. These results suggest that skunk CL appear to metabolize steroids in a manner similar to CL of other mustelids such as the ferret and American badger.<\/jats:p>","DOI":"10.1530\/jrf.0.0720495","type":"journal-article","created":{"date-parts":[[2004,3,20]],"date-time":"2004-03-20T01:55:52Z","timestamp":1079747752000},"page":"495-502","update-policy":"https:\/\/doi.org\/10.1530\/rep\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Steroid metabolism in corpora lutea of the western spotted skunk (\n                    <i>Spilogale putorius latifrons<\/i>\n                    )"],"prefix":"10.1093","volume":"72","author":[{"given":"R.","family":"Ravindra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Bhatia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Mead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,11,1]]},"container-title":["Reproduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/72\/2\/495\/64852011\/jrf_72_2_031.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/reproduction\/article-pdf\/72\/2\/495\/64852011\/jrf_72_2_031.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T20:18:07Z","timestamp":1767817087000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/72\/2\/495\/8282793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,11,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1984,11,1]]}},"URL":"https:\/\/doi.org\/10.1530\/jrf.0.0720495","relation":{},"ISSN":["1470-1626","1741-7899"],"issn-type":[{"value":"1470-1626","type":"print"},{"value":"1741-7899","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1984,11,1]]},"published":{"date-parts":[[1984,11,1]]}}}