{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T04:07:27Z","timestamp":1767845247553,"version":"3.49.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1989,9,1]],"date-time":"1989-09-01T00:00:00Z","timestamp":620611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":["reproduction-online.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1989,9,1]]},"abstract":"<jats:p>Summary. Five gilts each received intraluteal implants releasing about 4\u00b74 \u00b1 1\u00b71 (Group 1), 15\u00b70 \u00b1 1\u00b71 (Group 2) or 22\u00b74 \u00b1 1\u00b70 (Group 3) \u03bcgoestradiol\/day as determined by in-vitro incubation of implants of similar weight and oestradiol content. On Day 11 of the oestrous cycle (Day 0 = first day of oestrus), 3 CL in one ovary received oestradiol implants, 3 CL in the other ovary received vehicle implants, and all other CL in both ovaries served as uninjected control CL. An additional group of 6 animals served as controls and included 4 animals receiving bilateral vehicle implants (3 CL per ovary) on Day 11 and 2 unoperated gilts. All animals were slaughtered on Day 19 of their oestrous cycle, and the weight, progesterone content and concentration of each CL were determined. In Group 3 gilts, luteal weight, progesterone content and concentration were greater by 68\u00b77 \u00b1 24\u00b70 mg, 6\u00b754 \u00b1 1\u00b733 \u03bcg and 7\u00b754 \u00b1 2\u00b700 ng\/ml respectively (P &amp;lt; 0\u00b701) in oestradiol-implanted CL than in vehicle-implanted CL, which appeared to be similar to uninjected control CL. No differences were seen between oestradiol-17\u03b2 and vehicle-treated CL in CL from gilts in Groups 1 or 2. All CL of Group 3 gilts were heavier and contained a greater content and concentration of progesterone (P &amp;lt; 0\u00b701) than gilts in Groups 1 and 2, and in controls for which the values were similar. These results demonstrate that exogenous oestradiol can directly stimulate the growth of an individual CL; however, the oestradiol release rate must be high enough to maintain all CL bilaterally before this effect is seen.<\/jats:p>\n                  <jats:p>Keywords: corpus luteum; oestradiol-17\u03b2; luteotrophin; progesterone; pigs<\/jats:p>","DOI":"10.1530\/jrf.0.0870125","type":"journal-article","created":{"date-parts":[[2004,3,20]],"date-time":"2004-03-20T01:55:52Z","timestamp":1079747752000},"page":"125-131","update-policy":"https:\/\/doi.org\/10.1530\/rep\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":39,"title":["Direct luteotrophic effect of oestradiol-17\u03b2 on pig corpora lutea"],"prefix":"10.1093","volume":"87","author":[{"given":"A. J.","family":"Conleyt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. P.","family":"Ford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1989,9,1]]},"container-title":["Reproduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/87\/1\/125\/8279921","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/87\/1\/125\/8279921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T20:07:45Z","timestamp":1767816465000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/reproduction\/article\/87\/1\/125\/8279921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,9,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1989,9,1]]}},"URL":"https:\/\/doi.org\/10.1530\/jrf.0.0870125","relation":{},"ISSN":["1470-1626","1741-7899"],"issn-type":[{"value":"1470-1626","type":"print"},{"value":"1741-7899","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1989,9,1]]},"published":{"date-parts":[[1989,9,1]]}}}